Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Rachel V, Purcell"'
Autor:
Euan J. Rodger, Gregory Gimenez, Priyadarshana Ajithkumar, Peter A. Stockwell, Suzan Almomani, Sarah A. Bowden, Anna L. Leichter, Antonio Ahn, Sharon Pattison, John L. McCall, Sebastian Schmeier, Frank A. Frizelle, Michael R. Eccles, Rachel V. Purcell, Aniruddha Chatterjee
Publikováno v:
iScience, Vol 26, Iss 6, Pp 106986- (2023)
Summary: Colorectal cancer (CRC) is a leading cause of morbidity and mortality worldwide. The majority of CRC deaths are caused by tumor metastasis, even following treatment. There is strong evidence for epigenetic changes, such as DNA methylation, a
Externí odkaz:
https://doaj.org/article/55687d4519234db4bf4b68b7a5ae5db5
Autor:
Priyadarshana Ajithkumar, Gregory Gimenez, Peter A. Stockwell, Suzan Almomani, Sarah A. Bowden, Anna L. Leichter, Antonio Ahn, Sharon Pattison, Sebastian Schmeier, Frank A. Frizelle, Michael R. Eccles, Rachel V. Purcell, Euan J. Rodger, Aniruddha Chatterjee
Publikováno v:
Data, Vol 9, Iss 1, p 8 (2023)
Sequencing-based genome-wide DNA methylation, gene expression studies and associated data on paired colorectal cancer (CRC) primary and liver metastasis are very limited. We have profiled the DNA methylome and transcriptome of matched primary CRC and
Externí odkaz:
https://doaj.org/article/f34097822278464bb35e8c3ac67bf4d0
Publikováno v:
Gut Pathogens, Vol 14, Iss 1, Pp 1-7 (2022)
Abstract Background Enterotoxigenic Bacteroides fragilis (ETBF) has been implicated in colorectal carcinogenesis through the actions of its toxin, B. fragilis toxin (BFT). Studies on colorectal cell lines have shown that treatment with BFT causes dis
Externí odkaz:
https://doaj.org/article/20c18d3aa6cb448895b13ab03cf74638
Publikováno v:
Annals of Coloproctology, Vol 37, Iss 4, Pp 196-203 (2021)
Diverticulosis of the colon is a common condition in Western countries and most patients will remain asymptomatic, but some will present with symptoms of acute diverticulitis or bleeding. Our understanding of diverticulosis is evolving but is mostly
Externí odkaz:
https://doaj.org/article/1aa8328382a34722b147c7ab87383e2e
Autor:
Alexandra J. Noble, Rachel V. Purcell, Alex T. Adams, Ying K. Lam, Paulina M. Ring, Jessica R. Anderson, Amy J. Osborne
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
Epidemiological and associative research from humans and animals identifies correlations between the environment and health impacts. The environment—health inter-relationship is effected through an individual’s underlying genetic variation and me
Externí odkaz:
https://doaj.org/article/6e72812f0a3f4f12a8136595711198f1
Publikováno v:
PLoS ONE, Vol 17, Iss 6 (2022)
Background Carriage of certain bacterial species may represent potential biomarkers of colorectal cancer (CRC). Prominent among these is Fusobacterium nucleatum. We explored the association of F. nucleatum DNA in stool samples with the presence of co
Externí odkaz:
https://doaj.org/article/41a28ce5040844f8834f90bd617b3c6a
Publikováno v:
BMC Cancer, Vol 19, Iss 1, Pp 1-9 (2019)
Abstract Background Post-surgical staging is the mainstay of prognostic stratification for colorectal cancer (CRC). Here, we compare TNM staging to consensus molecular subtyping (CMS) and assess the value of subtyping in addition to stratification by
Externí odkaz:
https://doaj.org/article/8497c88f6b4e4fa6b1cba94d32ee1910
Autor:
William S Taylor, John Pearson, Allison Miller, Sebastian Schmeier, Frank A Frizelle, Rachel V Purcell
Publikováno v:
PLoS ONE, Vol 15, Iss 5, p e0233170 (2020)
BACKGROUND:Recent evidence suggests a role for the gut microbiome in the development and progression of many diseases and many studies have been carried out to analyse the microbiome using a variety of methods. In this study, we compare MinION sequen
Externí odkaz:
https://doaj.org/article/721cf919042e4a1481cfa2a7c3816bd4
Autor:
Rachel V. Purcell, Nadeem O. Kaakoush, Hazel M. Mitchell, John F. Pearson, Jacqueline I. Keenan
Publikováno v:
International Journal of Microbiology, Vol 2018 (2018)
Crohn’s disease (CD) is an inflammatory disease of the gastrointestinal tract, with a rising incidence worldwide, particularly in children. CD is thought to arise due to an immune response to environmental factors. The role of bacteria in CD has re
Externí odkaz:
https://doaj.org/article/8606f3ae8cc545f59ddac8e496a50f6d
Autor:
Rachel V. Purcell, Frank A. Frizelle, Michael J. O'Grady, Sajith C. Senadeera, Christopher Wakeman, Greg A. Turner, Andrew McCombie
Publikováno v:
ANZ Journal of Surgery. 91:2110-2114
BACKGROUND Once considered to be a congenital condition, the epidemiology of right-sided colonic diverticulosis (RCD) is evolving. Acute diverticulitis (AD) is a complication of RCD which is frequently misdiagnosed as appendicitis, resulting in unnec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8107a23261ff738abc03f080b3a96e67
https://doi.org/10.1111/ans.16995
https://doi.org/10.1111/ans.16995