Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Rachel T. Giorgio"'
Publikováno v:
PLoS Pathogens, Vol 20, Iss 2, p e1012033 (2024)
The host environment is of critical importance for antibiotic efficacy. By impacting bacterial machineries, stresses encountered by pathogens during infection promote the formation of phenotypic variants that are transiently insensitive to the action
Externí odkaz:
https://doaj.org/article/73a02194fe3e49c5bec32e0733aa8406
Publikováno v:
PLoS Pathogens, Vol 18, Iss 11, p e1010963 (2022)
Genetically susceptible bacteria can escape the action of bactericidal antibiotics through antibiotic tolerance or persistence. However, one major difference between the two phenomena is their distinct penetrance within an isogenic population. While
Externí odkaz:
https://doaj.org/article/832591c5f5bc4ca483cca1ff2813bc3c
Autor:
Hailong Zhang, Abdelrahim Zoued, Bolutife Fakoya, Rachel T. Giorgio, Ting Zhang, Matthew K. Waldor, Brandon Sit, Carole J. Kuehl
Publikováno v:
Nature Chemical Biology. 17:1199-1208
The microbial cell surface is a site of critical microbe–host interactions that often control infection outcomes. Defining the set of host proteins present at this interface has been challenging. Here we used a surface-biotinylation approach couple
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4670813e2d1d063b76fc93ea3a94f770
https://doi.org/10.1038/s41589-021-00894-4
https://doi.org/10.1038/s41589-021-00894-4
Autor:
Laurent Dubois, Sophie Helaine, Stephen A Hare, Alexander M J Hall, Rhodri M. L. Morgan, Tyler A Sisley, Rachel T. Giorgio, Grzegorz J Grabe, Julian A Rycroft
Publikováno v:
Nature Chemical Biology. 17:1296-1304
Toxin-antitoxin (TA) systems are a large family of genes implicated in the regulation of bacterial growth and its arrest in response to attacks. These systems encode nonsecreted toxins and antitoxins that specifically pair, even when present in sever
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a78187a7fb8d24fd2816829addfac2ab
https://doi.org/10.1038/s41589-021-00862-y
https://doi.org/10.1038/s41589-021-00862-y
Publikováno v:
Journal of Bacteriology. 203
The function of cvpA, a bacterial gene predicted to encode an inner membrane protein, is largely unknown. Early studies in E. coli linked cvpA to Colicin V secretion and recent work revealed that it is required for robust intestinal colonization by d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f52b8b2695946789480b519aeaa810ea
https://doi.org/10.1128/jb.00661-20
https://doi.org/10.1128/jb.00661-20
Autor:
Abdelrahim, Zoued, Hailong, Zhang, Ting, Zhang, Rachel T, Giorgio, Carole J, Kuehl, Bolutife, Fakoya, Brandon, Sit, Matthew K, Waldor
Publikováno v:
Nature chemical biology. 17(11)
The microbial cell surface is a site of critical microbe-host interactions that often control infection outcomes. Defining the set of host proteins present at this interface has been challenging. Here we used a surface-biotinylation approach coupled
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::87516fb33d5991cc5675968e87db288a
https://pubmed.ncbi.nlm.nih.gov/34675415
https://pubmed.ncbi.nlm.nih.gov/34675415
Autor:
Ting Zhang, Matthew K. Waldor, Rachel T. Giorgio, Hailong Zhang, Brandon Sit, Carole J. Kuehl, Bolutife Fakoya, Abdelrahim Zoued
SummaryThe microbial cell surface is a critical site of microbe-host interactions that often control infection outcomes. Here, using the infant rabbit model of cholera, which provides an abundant source of in vivo Vibrio cholerae cells and diarrheal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::38366c786528753233e7906df308f2a6
https://doi.org/10.1101/2021.01.05.425471
https://doi.org/10.1101/2021.01.05.425471
Publikováno v:
J Bacteriol
The function of cvpA, a bacterial gene predicted to encode an inner membrane protein, is largely unknown. Early studies in Escherichia coli linked cvpA to colicin V secretion, and recent work revealed that it is required for robust intestinal coloniz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8259da60617ec75f67b85c90f8193e0d
https://pubmed.ncbi.nlm.nih.gov/33361192
https://pubmed.ncbi.nlm.nih.gov/33361192
The function ofcvpA, a bacterial gene predicted to encode an inner membrane protein, is largely unknown. Early studies inE. colilinkedcvpAto Colicin V secretion and recent work revealed that it is required for robust intestinal colonization by divers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::34d07f044629683136fa9c2ee64eda11
https://doi.org/10.1101/2020.09.25.314492
https://doi.org/10.1101/2020.09.25.314492
Autor:
Jacob E. Lazarus, Rachel T. Giorgio, Carole J. Kuehl, Matthew K. Waldor, Brigid M. Davis, Alyson R. Warr
Publikováno v:
Applied and environmental microbiology. 85(16)
Despite the advent of new techniques for genetic engineering of bacteria, allelic exchange through homologous recombination remains an important tool for genetic analysis. Currently, sacB-based vector systems are often used for allelic exchange, but
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5416400a18b4d8638ffb0178769e668e
https://pubmed.ncbi.nlm.nih.gov/31201277
https://pubmed.ncbi.nlm.nih.gov/31201277