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pro vyhledávání: '"Rachel Steuerman"'
Publikováno v:
Reviews in Endocrinology and Metabolism.
In accordance with the link between increased GH and IGF-I secretion and cancer, we found that homozygous patients with Laron syndrome (severe GH insensitivity) and low to undetectable serum IGF-I are protected from developing cancer even if treated
Congenital IGF1 deficiency tends to confer protection against post-natal development of malignancies
Publikováno v:
European journal of endocrinology. 164(4)
ObjectiveTo investigate whether congenital IGF1 deficiency confers protection against development of malignancies, by comparing the prevalence of malignancies in patients with congenital (secondary) deficiency of IGF1 with the prevalence of cancer in
Publikováno v:
Laron Syndrome-From Man to Mouse ISBN: 9783642111822
Reviewing the prevalence of malignancies in our cohort of 64 Laron syndrome patients and of 102 of their first degree relatives we registered none in the homozygous patients with LS, but 11 instances of cancer in the heterozygous family members.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d610695db2d8bc66ed62ce7ac4e986fd
https://doi.org/10.1007/978-3-642-11183-9_40
https://doi.org/10.1007/978-3-642-11183-9_40
Autor:
Rachel Steuerman
Publikováno v:
European Journal of Endocrinology; Apr2011, Vol. 164 Issue 4, p485-489, 5p