Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Rachel Spruce"'
Autor:
Celina Whalley, Karl Payne, Enric Domingo, Andrew Blake, Susan Richman, Jill Brooks, Nikolaos Batis, Rachel Spruce, S-CORT Consortium, Hisham Mehanna, Paul Nankivell, Andrew D. Beggs
Publikováno v:
Epigenomes, Vol 5, Iss 1, p 6 (2021)
Background: Abnormal CpG methylation in cancer is ubiquitous and generally detected in tumour specimens using a variety of techniques at a resolution encompassing single CpG loci to genome wide coverage. Analysis of samples with very low DNA inputs,
Externí odkaz:
https://doaj.org/article/014cbacdfccb4846af47ffcf7deef069
Autor:
Mengxi Wu, David T.W. Wong, Elliot Abemayor, Rachel Spruce, Liang Li, Nikolaos Batis, Jinxin Zhang, Michael Tu, Feng Li, Yong Kim, Chuyi Chen, Tony Jun Huang, David Chia, Zeyu Wang, Joseph Rufo, Jordan Cheng, Hisham Mehanna, Shujie Yang
Publikováno v:
The Journal of Molecular Diagnostics. 22:50-59
Previous efforts to evaluate the detection of human papilloma viral (HPV) DNA in whole saliva as a diagnostic measure for HPV-associated oropharyngeal cancer (HPV-OPC) have not shown sufficient clinical performance. We hypothesize that salivary exoso
Autor:
Neeraj Lal, Riyue Bao, Sandra Ventorin Von Zeidler, Arun Khattri, Helen R Valentine, Albert N. Menezes, Jean-Baptiste Cazier, Hisham Mehanna, Tanguy Y. Seiwert, Maha Ibrahim, Steven P. Lee, Jonathan J Deeks, Lucinda Archer, Daniel A. Tennant, Andrew D Beggs, Christopher Bagnall, Margaret Hartley, Nikolaos Batis, Kalu U.E. Ogbureke, Baksho Kaul, Jill Brooks, Gary Middleton, Jennifer L. Bryant, Catharine M L West, Gordon B. Ryan, Rachel Spruce, Benjamin E. Willcox
Publikováno v:
Clinical Cancer Research. 25:5315-5328
Purpose: Intratumoral hypoxia and immunity have been correlated with patient outcome in various tumor settings. However, these factors are not currently considered for treatment selection in head and neck cancer (HNC) due to lack of validated biomark
Autor:
Paul Nankivell, Jill Brooks, Andrew D Beggs, Karl Payne, Enric Domingo, Hisham Mehanna, Susan D. Richman, Nikolaos Batis, Andrew Blake, Celina Whalley, Rachel Spruce
BackgroundCpG methylation in cancer is ubiquitous and generally detected in tumour specimens using a variety of techniques at a resolution encompassing single CpG loci to genome wide. Analysis of samples with very low DNA inputs, such as formalin fix
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b0e7b31cae22be50a67d54cc2412594
Autor:
Zeyu, Wang, Feng, Li, Joseph, Rufo, Chuyi, Chen, Shujie, Yang, Liang, Li, Jinxin, Zhang, Jordan, Cheng, Yong, Kim, Mengxi, Wu, Elliot, Abemayor, Michael, Tu, David, Chia, Rachel, Spruce, Nikolaos, Batis, Hisham, Mehanna, David T W, Wong, Tony Jun, Huang
Publikováno v:
J Mol Diagn
Previous efforts to evaluate the detection of human papilloma viral (HPV) DNA in whole saliva as a diagnostic measure for HPV-associated oropharyngeal cancer (HPV-OPC) have not shown sufficient clinical performance. We hypothesize that salivary exoso
Autor:
Jill Brooks, Margaret Hartley, Nicholas M. Barnes, Joanna L Parish, Andrew D. Southam, Jennifer L. Bryant, Anna Clara Franke, Nikolaos Batis, Farhat L. Khanim, Sally Roberts, Gordon B. Ryan, Hisham Mehanna, Gabriella Clancey, Rachel Spruce
Publikováno v:
Scopus-Elsevier
Oncotarget
Oncotarget
// Jennifer Bryant 1 , * , Nikolaos Batis 1 , * , Anna Clara Franke 1 , Gabriella Clancey 1 , Margaret Hartley 1 , Gordon Ryan 1 , Jill Brooks 1 , Andrew D. Southam 4 , 5 , Nicholas Barnes 2 , 7 , Joanna Parish 2 , Sally Roberts 2 , Farhat Khanim 6 ,
Autor:
Dominique Rosillon, Alex Vorsters, Oladejo Olaleye, Gypsyamber D'Souza, Hisham Mehanna, Jennifer L. Bryant, Tyler S Bryant, Karly S. Louie, Linda Struijk, Nikolaos Batis, Jaspreet Babrah, Sylvia Taylor, June Jones, Rachel Spruce, Anco Molijn
Publikováno v:
Clinical infectious diseases
BackgroundOropharyngeal cancer incidence is rapidly rising due to human papillomavirus (HPV) type 16 infection. The dearth of data on effectiveness of national female-only vaccination programs in preventing oral HPV infection and potential herd immun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0dd841929afd8c93128609496f167c74
https://europepmc.org/articles/PMC6763631/
https://europepmc.org/articles/PMC6763631/
Autor:
Karl Payne, Hisham Mehanna, Rachel Spruce, Jill Brooks, Nikolaos Batis, Paul Nankivell, Graham S. Taylor
Publikováno v:
British Journal of Oral and Maxillofacial Surgery. 58:e159
Autor:
Anthony Kong, Rachel Spruce, Amanda Kirkham, Hisham Mehanna, Joseph J. Sacco, J. Good, Martin Forster, Christina Yap, Kevin J. Harrington, Laura Llewellyn, P. Murray, Gary Middleton, S. Schipani, Joanna L Parish, Joshua Savage, Rhys Mant
Publikováno v:
BMJ Open
IntroductionPatients with head and neck squamous cell carcinoma with locally advanced disease often require multimodality treatment with surgery, radiotherapy and/or chemotherapy. Adjuvant radiotherapy with concurrent chemotherapy is offered to patie
Autor:
N. Würdemann, Terence M. Jones, Max Robinson, Anders Näsman, Nikolaos Batis, David Hebbelstrup Jensen, Stefan Gattenlöhner, Hisham Mehanna, Eva Munck-Wikland, Christian Dehlendorff, Shachi Jenny Sharma, Katalin Kiss, Christian Grønhøj, Tina Dalianis, Kevin J. Harrington, Elo Andersen, Linda Marklund, Christian von Buchwald, Jeppe Friborg, Steffen Wagner, Jens Peter Klussmann, Claus Wittekindt, Stuart Winter, Torbjörn Ramqvist, Rachel Spruce
Publikováno v:
British Journal of Cancer
Grønhøj, C, Jensen, D H, Dehlendorff, C, Marklund, L, Wagner, S, Mehanna, H, Munck-Wikland, E, Ramqvist, T, Näsman, A, Wittekindt, C, Würdemann, N, Sharma, S J, Gattenlöhner, S, Kiss, K, Andersen, E, Spruce, R, Batis, N, Robinson, M, Harrington, K, Winter, S, Jones, T M, Klussmann, J P, Dalianis, T, Friborg, J & von Buchwald, C 2018, ' Development and external validation of nomograms in oropharyngeal cancer patients with known HPV-DNA status : a European Multicentre Study (OroGrams) ', British Journal of Cancer, vol. 118, no. 12, pp. 1672-1681 . https://doi.org/10.1038/s41416-018-0107-9
BRITISH JOURNAL OF CANCER
Grønhøj, C, Jensen, D H, Dehlendorff, C, Marklund, L, Wagner, S, Mehanna, H, Munck-Wikland, E, Ramqvist, T, Näsman, A, Wittekindt, C, Würdemann, N, Sharma, S J, Gattenlöhner, S, Kiss, K, Andersen, E, Spruce, R, Batis, N, Robinson, M, Harrington, K, Winter, S, Jones, T M, Klussmann, J P, Dalianis, T, Friborg, J & von Buchwald, C 2018, ' Development and external validation of nomograms in oropharyngeal cancer patients with known HPV-DNA status : a European Multicentre Study (OroGrams) ', British Journal of Cancer, vol. 118, no. 12, pp. 1672-1681 . https://doi.org/10.1038/s41416-018-0107-9
BRITISH JOURNAL OF CANCER
BACKGROUND: The proxy marker for human papillomavirus (HPV), p16, is included in the new AJCC 8th/UICC 8th staging system, but due to incongruence between p16 status and HPV infection, single biomarker evaluation could lead to misallocation of patien