Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Rachel Spiering"'
Autor:
Rachel Spiering, Manon A. A. Jansen, Matthew J. Wood, Anshorulloh A. Fath, Oliver Eltherington, Amy E. Anderson, Arthur G. Pratt, Willem van Eden, John D. Isaacs, Femke Broere, Catharien M. U. Hilkens
Publikováno v:
Journal of Translational Medicine, Vol 17, Iss 1, Pp 1-12 (2019)
Abstract Background Autologous tolerogenic dendritic cells (tolDC) are a promising therapeutic strategy for inflammatory arthritis (IA) as they can regulate autoantigen-specific T cell responses. Here, we investigated two outstanding priorities for c
Externí odkaz:
https://doaj.org/article/755e2b1899d548a39883bf1a0343da09
Autor:
Manon A. A. Jansen, Rachel Spiering, Irene S. Ludwig, Willem van Eden, Catharien M. U. Hilkens, Femke Broere
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Tolerogenic dendritic cells (tolDCs) are a promising treatment modality for diseases caused by a breach in immune tolerance, such as rheumatoid arthritis. Current medication for these diseases is directed toward symptom suppression but no real cure i
Externí odkaz:
https://doaj.org/article/cfc8baf47ce4400e9b5bc2d06f8fdd6a
Autor:
Anke Fuchs, Mateusz Gliwiński, Nathali Grageda, Rachel Spiering, Abul K. Abbas, Silke Appel, Rosa Bacchetta, Manuela Battaglia, David Berglund, Bruce Blazar, Jeffrey A. Bluestone, Martin Bornhäuser, Anja ten Brinke, Todd M. Brusko, Nathalie Cools, Maria Cristina Cuturi, Edward Geissler, Nick Giannoukakis, Karolina Gołab, David A. Hafler, S. Marieke van Ham, Joanna Hester, Keli Hippen, Mauro Di Ianni, Natasa Ilic, John Isaacs, Fadi Issa, Dorota Iwaszkiewicz-Grześ, Elmar Jaeckel, Irma Joosten, David Klatzmann, Hans Koenen, Cees van Kooten, Olle Korsgren, Karsten Kretschmer, Megan Levings, Natalia Maria Marek-Trzonkowska, Marc Martinez-Llordella, Djordje Miljkovic, Kingston H.G. Mills, Joana P. Miranda, Ciriaco A. Piccirillo, Amy L. Putnam, Thomas Ritter, Maria Grazia Roncarolo, Shimon Sakaguchi, Silvia Sánchez-Ramón, Birgit Sawitzki, Ljiljana Sofronic-Milosavljevic, Megan Sykes, Qizhi Tang, Marta Vives-Pi, Herman Waldmann, Piotr Witkowski, Kathryn J. Wood, Silvia Gregori, Catharien M. U. Hilkens, Giovanna Lombardi, Phillip Lord, Eva M. Martinez-Caceres, Piotr Trzonkowski
Publikováno v:
Frontiers in Immunology, Vol 8 (2018)
Cellular therapies with CD4+ T regulatory cells (Tregs) hold promise of efficacious treatment for the variety of autoimmune and allergic diseases as well as posttransplant complications. Nevertheless, current manufacturing of Tregs as a cellular medi
Externí odkaz:
https://doaj.org/article/6e6307c0ff3e4a65bfd0edfff5a979c4
Autor:
Phillip Lord, Rachel Spiering, Juan C. Aguillon, Amy E. Anderson, Silke Appel, Daniel Benitez-Ribas, Anja ten Brinke, Femke Broere, Nathalie Cools, Maria Cristina Cuturi, Julie Diboll, Edward K. Geissler, Nick Giannoukakis, Silvia Gregori, S. Marieke van Ham, Staci Lattimer, Lindsay Marshall, Rachel A. Harry, James A. Hutchinson, John D. Isaacs, Irma Joosten, Cees van Kooten, Ascension Lopez Diaz de Cerio, Tatjana Nikolic, Haluk Barbaros Oral, Ljiljana Sofronic-Milosavljevic, Thomas Ritter, Paloma Riquelme, Angus W. Thomson, Massimo Trucco, Marta Vives-Pi, Eva M. Martinez-Caceres, Catharien M.U. Hilkens
Publikováno v:
PeerJ, Vol 4, p e2300 (2016)
Cellular therapies with tolerogenic antigen-presenting cells (tolAPC) show great promise for the treatment of autoimmune diseases and for the prevention of destructive immune responses after transplantation. The methodologies for generating tolAPC va
Externí odkaz:
https://doaj.org/article/9ff191435bf7451cb77f534680bb43e6
Autor:
Rachel Spiering, Ruurd van der Zee, Josée Wagenaar, Dimos Kapetis, Francesca Zolezzi, Willem van Eden, Femke Broere
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e46336 (2012)
Tolerogenic dendritic cells (DCs) can induce regulatory T cells and dampen pathogenic T cell responses. Therefore, they are possible therapeutic targets in autoimmune diseases. In this study we investigated whether mouse tolerogenic DCs are induced b
Externí odkaz:
https://doaj.org/article/de0de426dad7468590871997368f6c9f
Autor:
Oliver Eltherington, Amy E. Anderson, Rachel Spiering, Catharien M. U. Hilkens, Matthew Wood, Femke Broere, Manon A A Jansen, John D. Isaacs, Anshorulloh A. Fath, Arthur G. Pratt, Willem van Eden
Publikováno v:
Journal of Translational Medicine
Journal of Translational Medicine, Vol 17, Iss 1, Pp 1-12 (2019)
Journal of Translational Medicine, 17(1). BioMed Central
Journal of Translational Medicine, Vol 17, Iss 1, Pp 1-12 (2019)
Journal of Translational Medicine, 17(1). BioMed Central
Background Autologous tolerogenic dendritic cells (tolDC) are a promising therapeutic strategy for inflammatory arthritis (IA) as they can regulate autoantigen-specific T cell responses. Here, we investigated two outstanding priorities for clinical d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3da0ec053278ffccdda1da0cf4d0437f
https://pubmed.ncbi.nlm.nih.gov/31727095
https://pubmed.ncbi.nlm.nih.gov/31727095
Autor:
Manon A A, Jansen, Rachel, Spiering, Irene S, Ludwig, Willem, van Eden, Catharien M U, Hilkens, Femke, Broere
Publikováno v:
Frontiers in Immunology
Tolerogenic dendritic cells (tolDCs) are a promising treatment modality for diseases caused by a breach in immune tolerance, such as rheumatoid arthritis. Current medication for these diseases is directed toward symptom suppression but no real cure i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8242777d697c48f1225c511306af4c2c
https://pubmed.ncbi.nlm.nih.gov/31555285
https://pubmed.ncbi.nlm.nih.gov/31555285
Autor:
Simon Milling, Gary Reynolds, Adam Leckenby, John D. Isaacs, Kenneth S. Rankin, Matthew J. Wood, Rachel Spiering, Catharien M. U. Hilkens, Muzlifah Haniffa, Arthur G. Pratt
Publikováno v:
JCI insight. 4(2)
Osteoarthritis (OA) is a leading cause of disability, globally. Despite an emerging role for synovial inflammation in OA pathogenesis, attempts to target inflammation therapeutically have had limited success. A better understanding of the cellular an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de6de2d2fb8c3ba129dfb64a87328fc6
https://pubmed.ncbi.nlm.nih.gov/30674730
https://pubmed.ncbi.nlm.nih.gov/30674730
Autor:
Bram Margry, Cathleen Petzold, Aad Hoek, Josée P A Wagenaar-Hilbers, Willem van Eden, Rachel Spiering, Femke Broere, Ruurd van der Zee, Chantal Keijzer, Karsten Kretschmer
Publikováno v:
The Journal of Immunology. 194:4804-4813
Previous studies in mouse models of autoimmune diabetes and encephalomyelitis have indicated that the selective delivery of self-antigen to the endocytic receptor DEC205 on steady-state dendritic cells (DCs) may represent a suitable approach to induc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0153bb457e32b8ebeb1bb14c46f91fc0
https://doi.org/10.4049/jimmunol.1400986
https://doi.org/10.4049/jimmunol.1400986
Autor:
Femke Broere, Willem van Eden, Manon A A Jansen, Rachel Spiering, Catharien M. U. Hilkens, Jacob M van Laar, John D. Isaacs
Publikováno v:
Immunology, 153(1), 51. Blackwell Publishing Ltd
Immunology
Immunology
Tolerogenic dendritic cells (tolDCs) are a promising therapeutic tool to restore immune tolerance in autoimmune diseases. The rationale of using tolDCs is that they can specifically target the pathogenic T cell response, while leaving other, protecti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bed1f626218665284b9ec6146121a858
https://doi.org/10.1111/imm.12811
https://doi.org/10.1111/imm.12811