Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Rachel Schiller"'
Autor:
Louise J. Walport, Richard J. Hopkinson, Rasheduzzaman Chowdhury, Rachel Schiller, Wei Ge, Akane Kawamura, Christopher J. Schofield
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
While reversal of lysine methylation on histone tails is a well-established mechanism to tune gene expression, the existence of a similar arginine demethylation process is controversial. Here, the authors show that some jumonji enzymes possess both l
Externí odkaz:
https://doaj.org/article/b3dc6971dc6349f5a32b481bb23ad534
Autor:
Akane Kawamura, Rachel Schiller, Richard J. Hopkinson, Louise J. Walport, Rasheduzzaman Chowdhury, Christopher J. Schofield, Yijia Zhang, Joanna Bonnici
Publikováno v:
FEBS Letters
Febs Letters
Febs Letters
N‐Methylation of lysyl residues is widely observed on histone proteins. Using isolated enzymes, we report mechanistic and structural studies on histone lysine demethylase (KDM)‐catalysed demethylation of N ε‐methylated lysine 26 on histone 1 i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b41479872714cf56da2a7738b8087eb
http://hdl.handle.net/10044/1/65213
http://hdl.handle.net/10044/1/65213
Autor:
Rachel Schiller, Jacob T. Bush, G Scozzafava, James Wickens, Ganesha Rai, Bryan T. Mott, Akane Kawamura, Anthony Tumber, Clarisse Lejeune, Mun Chiang Chan, Tzu-Lan Yeh, James S. O. McCullagh, Hwanho Choi, David J. Maloney, Christopher J. Schofield
Publikováno v:
ChemMedChem
Chemmedchem
Chemmedchem
The 2-oxoglutarate (2OG)-dependent Jumonji C domain (JmjC) family is the largest family of histone lysine demethylases. There is interest in developing small-molecule probes that modulate JmjC activity to investigate their biological roles. 5-Carboxy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1052dfdee934f6f0cda848f1ab26d89f
https://ora.ox.ac.uk/objects/uuid:cc2a3734-4a5d-4aa5-b621-f371f424091f
https://ora.ox.ac.uk/objects/uuid:cc2a3734-4a5d-4aa5-b621-f371f424091f
Autor:
Louise J, Walport, Richard J, Hopkinson, Rasheduzzaman, Chowdhury, Rachel, Schiller, Wei, Ge, Akane, Kawamura, Christopher J, Schofield
Publikováno v:
Nature Communications
While the oxygen-dependent reversal of lysine Nɛ-methylation is well established, the existence of bona fide Nω-methylarginine demethylases (RDMs) is controversial. Lysine demethylation, as catalysed by two families of lysine demethylases (the flav
Autor:
Rachel Schiller
Publikováno v:
Asian Journal of Social Science. 39:489-507
Abstract Aceh, Indonesia is one of the few societies that have successfully navigated a post-disaster transition following simultaneous natural and man-made disasters. Since the August 2005 peace agreement, Aceh’s road to recovery from the 2004 Ind