Zobrazeno 1 - 10
of 173
pro vyhledávání: '"Rachel S Kelly"'
Autor:
Cynthia M Pérez, Jose M Ordovas, Katherine L Tucker, Meir J Stampfer, Dong D Wang, Liming Liang, Chao-Qiang Lai, Rachel S Kelly, David T W Wong, Danielle E Haslam, Clemens Wittenbecher, Marijulie Martínez, Chih-Hao Lee, Laurence D Parnell, Kaumudi J Joshipura
Publikováno v:
BMJ Open Diabetes Research & Care, Vol 9, Iss 1 (2021)
Introduction We investigated whether network analysis revealed clusters of coregulated metabolites associated with prevalent type 2 diabetes (T2D) among Puerto Rican adults.Research design and methods We used liquid chromatography-mass spectrometry t
Externí odkaz:
https://doaj.org/article/ead595bcd8b54bd5924e5e7694cc4b7f
Autor:
Amber Dahlin, Joanne E Sordillo, Michael McGeachie, Rachel S Kelly, Kelan G Tantisira, Sharon M Lutz, Jessica Lasky-Su, Ann Chen Wu
Publikováno v:
PLoS ONE, Vol 15, Iss 3, p e0229241 (2020)
While genome-wide association studies have identified genes involved in differential treatment responses to inhaled corticosteroids (ICS) in asthma, few studies have evaluated the potential effects of age in this context. A significant proportion of
Externí odkaz:
https://doaj.org/article/6d748f86e5374d829480687d73e802cd
Autor:
Rachel S Kelly, Jessica Lasky-Su, Sai-Ching J Yeung, Richard M Stone, Jeffrey M Caterino, Sean C Hagan, Gary H Lyman, Lindsey R Baden, Brett E Glotzbecker, Christopher J Coyne, Christopher W Baugh, Daniel J Pallin
Publikováno v:
PLoS ONE, Vol 13, Iss 5, p e0197049 (2018)
BACKGROUND:Cancer chemotherapy-associated febrile neutropenia (FN) is a common condition that is deadly when bacteremia is present. Detection of bacteremia depends on culture, which takes days, and no accurate predictive tools applicable to the initi
Externí odkaz:
https://doaj.org/article/00b811d90a3c4c23a0a4c8ad53eec1fa
Autor:
Margherita De Marzio, Jessica Lasky-Su, Su H. Chu, Nicole Prince, Augusto A. Litonjua, Scott T. Weiss, Rachel S. Kelly, Kimberly R. Glass
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract Neurodevelopmental disorders are rapidly increasing in prevalence and have been linked to various environmental risk factors. Mounting evidence suggests a potential role of vitamin D in child neurodevelopment, though the causal mechanisms re
Externí odkaz:
https://doaj.org/article/1d1edbb3b6c2481c887cf027c88dcbb9
Autor:
Kevin Mendez, Ines Lains, Rachel S. Kelly, João Gil, Rufino Silva, John Miller, Demetrios G. Vavvas, Ivana Kim, Joan Miller, Liming Liang, Jessica A. Lasky-Su, Deeba Husain
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Age-related macular degeneration (AMD) is a leading cause of blindness worldwide, with a complex pathophysiology and phenotypic diversity. Here, we apply Similarity Network Fusion (SNF) to cluster AMD patients into putative metabolomics-deri
Externí odkaz:
https://doaj.org/article/3230ea83c28942a09c1a4962098ea2b8
Autor:
Rachel S Kelly, Thomas Lundh, Miquel Porta, Ingvar A Bergdahl, Domenico Palli, Ann-Sofie Johansson, Maria Botsivali, Paolo Vineis, Roel Vermeulen, Soterios A Kyrtopoulos, Marc Chadeau-Hyam, EnviroGenoMarkersProject Consortium
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e81892 (2013)
BACKGROUND: Cadmium (Cd) and lead (Pb) are hypothesised to be risk factors for non-Hodgkin's lymphoma (NHL), a group of haematological malignancies with a suspected environmental aetiology. Within the EnviroGenoMarkers study we utilised pre-diagnosti
Externí odkaz:
https://doaj.org/article/7987b01e0caf425da229fb060d010e4e
Autor:
Kevin M. Mendez, Sofina Begum, Anshul Tiwari, Rinku Sharma, Qingwen Chen, Rachel S. Kelly, Nicole Prince, Mengna Huang, Priyadarshini Kachroo, Su H. Chu, Yulu Chen, Kathleen Lee-Sarwar, David I. Broadhurst, Stacey N. Reinke, Robert Gerszten, Clary Clish, Lydiana Avila, Juan C. Celedón, Craig E. Wheelock, Scott T. Weiss, Michael McGeachie, Jessica A. Lasky-Su
Publikováno v:
EBioMedicine, Vol 102, Iss , Pp 105025- (2024)
Summary: Background: Lung function trajectories (LFTs) have been shown to be an important measure of long-term health in asthma. While there is a growing body of metabolomic studies on asthma status and other phenotypes, there are no prospective stud
Externí odkaz:
https://doaj.org/article/1da55660eee84901b30e4550ba08f293
Autor:
Nicole Prince, Rachel S. Kelly, Su H. Chu, Priyadarshini Kachroo, Yulu Chen, Kevin M. Mendez, Sofina Begum, Hans Bisgaard, Klaus Bønnelykke, Min Kim, Ofer Levy, Augusto A. Litonjua, Craig E. Wheelock, Scott T. Weiss, Bo L. Chawes, Jessica A. Lasky-Su
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-8 (2023)
Abstract Respiratory infections are a leading cause of morbidity and mortality in early life, and recurrent infections increase the risk of developing chronic diseases. The maternal environment during pregnancy can impact offspring health, but the fa
Externí odkaz:
https://doaj.org/article/ad6dafe46ea84769bc12cbb3f2c1820a
Autor:
Elena V. Feofanova, Michael R. Brown, Taryn Alkis, Astrid M. Manuel, Xihao Li, Usman A. Tahir, Zilin Li, Kevin M. Mendez, Rachel S. Kelly, Qibin Qi, Han Chen, Martin G. Larson, Rozenn N. Lemaitre, Alanna C. Morrison, Charles Grieser, Kari E. Wong, Robert E. Gerszten, Zhongming Zhao, Jessica Lasky-Su, NHLBI Trans-Omics for Precision Medicine (TOPMed), Bing Yu
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)
Abstract Circulating metabolite levels may reflect the state of the human organism in health and disease, however, the genetic architecture of metabolites is not fully understood. We have performed a whole-genome sequencing association analysis of bo
Externí odkaz:
https://doaj.org/article/fd8c3eb176234d4c8fc8bb86a09934a5
Autor:
Ines Lains, MD, PhD, Xikun Han, PhD, João Gil, MD, Joana Providencia, MD, Archana Nigalye, MD, Rodrigo Alvarez, MD, Vivian Paraskevi Douglas, MD, Kevin Mendez, MSc, Raviv Katz, BSc, Gregory Tsougranis, BSc, Jinglun Li, BSc, Rachel S. Kelly, PhD, Ivana K. Kim, MD, Jessica Lasky-Su, ScD, Rufino Silva, MD, PhD, Joan W. Miller, MD, Liming Liang, PhD, Demetrios Vavvas, MD, PhD, John B. Miller, MD, Deeba Husain, MD
Publikováno v:
Ophthalmology Science, Vol 4, Iss 1, Pp 100357- (2024)
Purpose: The most widely used classifications of age-related macular degeneration (AMD) and its severity stages still rely on color fundus photographs (CFPs). However, AMD has a wide phenotypic variability that remains poorly understood and is better
Externí odkaz:
https://doaj.org/article/f85fa775aca54aa681cfe9965278b9bf