Circadian regulation of the transcriptome in a complex polyploid crop

Autor: Hannah Rees, Rachel Rusholme-Pilcher, Paul Bailey, Joshua Colmer, Benjamen White, Connor Reynolds, Sabrina Jaye Ward, Benedict Coombes, Calum A. Graham, Luíza Lane de Barros Dantas, Antony N. Dodd, Anthony Hall

Publikováno v: PLoS Biology, Vol 20, Iss 10 (2022)

The circadian clock is a finely balanced timekeeping mechanism that coordinates programmes of gene expression. It is currently unknown how the clock regulates expression of homoeologous genes in polyploids. Here, we generate a high-resolution time-co

Externí odkaz: https://doaj.org/article/ded31548582c4dbd81f2fa4ccef9d1f9

Whole genome sequencing uncovers the structural and transcriptomic landscape of hexaploid wheat/Ambylopyrum muticum introgression lines

Autor: Ryan Joynson, Benedict Coombes, Caiyun Yang, Anthony Hall, Julie King, Stella Hubbart-Edwards, John P. Fellers, Ian P. King, Surbhi Grewal, Rachel Rusholme-Pilcher

Publikováno v: Plant biotechnology journal.

Wheat is a globally vital crop, but its limited genetic variation creates a challenge for breeders aiming to maintain or accelerate agricultural improvements over time. Introducing novel genes and alleles from wheat’s wild relatives into the wheat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fdbad9815a31009a62ac1e0186646c6
https://pubmed.ncbi.nlm.nih.gov/35598169

Interpreting machine learning models to investigate circadian regulation and facilitate exploration of clock function

Autor: Anna Paola Carrieri, Ritesh Krishna, Anthony Halll, Josh Colmer, Susan Duncan, Hannah Rees, Juan Manuel Crescente, Laura-Jayne Gardiner, Edward O. Pyzer-Knapp, Rachel Rusholme-Pilcher

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America
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Significance The circadian clock is an internal molecular 24-h timer that is critical to life on Earth. We describe a series of artificial intelligence (AI)– and machine learning (ML)–based approaches that enable more cost-effective analysis and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1378cd21de72019507cf44ffda060633
http://europepmc.org/articles/PMC8364196