Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Rachel Ruoff"'
Autor:
Rachel Ruoff, Hannah Weber, Ying Wang, Hongying Huang, Ellen Shapiro, David Fenyö, Michael J. Garabedian
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract MED19, a component of the mediator complex and a co-regulator of the androgen receptor (AR), is pivotal in prostate cancer cell proliferation. MED19 has two isoforms: a full-length “canonical” and a shorter “alternative” variant. Spe
Externí odkaz:
https://doaj.org/article/9d076138bbdb44f2b8123f663951ef45
Autor:
Maud Voisin, Elina Shrestha, Claire Rollet, Cyrus A. Nikain, Tatjana Josefs, Mélanie Mahé, Tessa J. Barrett, Hye Rim Chang, Rachel Ruoff, Jeffrey A. Schneider, Michela L. Garabedian, Chris Zoumadakis, Chi Yun, Bara Badwan, Emily J. Brown, Adam C. Mar, Robert J. Schneider, Ira J. Goldberg, Inés Pineda-Torra, Edward A. Fisher, Michael J. Garabedian
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-18 (2021)
Voisin et al. show that reducing phosphorylation at serine 196 of LXRα (LXRα pS196) in hematopoietic cells attenuates atherosclerosis and obesity of mice fed a high-fat diet. They find that the transcriptional activity of LXRα is reprogrammed in m
Externí odkaz:
https://doaj.org/article/c5802b4ff1e54135a67ab96e212ab5fd
Autor:
Prashanth Thevkar-Nagesh, Justine Habault, Maud Voisin, Sophie E Ruff, Susan Ha, Rachel Ruoff, Xi Chen, Shruti Rawal, Tarik Zahr, Gyongyi Szabo, Inez Rogatsky, Edward A Fisher, Michael J Garabedian
Publikováno v:
PLoS ONE, Vol 17, Iss 9, p e0272986 (2022)
Acyl-CoA synthetase 1 (ACSL1) is an enzyme that converts fatty acids to acyl-CoA-derivatives for lipid catabolism and lipid synthesis in general and can provide substrates for the production of mediators of inflammation in monocytes and macrophages.
Externí odkaz:
https://doaj.org/article/9d2578ffafa14325afa10509178736ab
Publikováno v:
PLoS Genetics, Vol 17, Iss 1, p e1008540 (2021)
Androgen deprivation therapy (ADT) is a mainstay of prostate cancer treatment, given the dependence of prostate cells on androgen and the androgen receptor (AR). However, tumors become ADT-resistant, and there is a need to understand the mechanism. O
Externí odkaz:
https://doaj.org/article/2f2165c7b85546f79a527a9d844c8c76
Autor:
Gregory David, Susan K. Logan, Nabeel Bardeesy, Rachel Ruoff, Patricia M. Finnerty, Rubén Fernández Rodríguez, Jessica Pellegrino, Teresa DiMauro, Petar Jelinic, Kathryn B. Grandinetti
Supplementary Figures 1-7 from Sin3B Expression Is Required for Cellular Senescence and Is Up-regulated upon Oncogenic Stress
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2866b2dd051e51ae62408778d235313d
https://doi.org/10.1158/0008-5472.22377686
https://doi.org/10.1158/0008-5472.22377686
Autor:
Susan K. Logan, Michael J. Garabedian, William L. Gerald, Myles Brown, Samir S. Taneja, S. Joseph Huang, Qianben Wang, Susan Ha, Rachel Ruoff, Paolo Mita, Jerome C. Nwachukwu
The androgen receptor (AR) directs diverse biological processes through interaction with coregulators such as AR trapped clone-27 (ART-27). Our results show that ART-27 is recruited to AR-binding sites by chromatin immunoprecipitation analysis. In ad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dc9db14f25f3740a287b2963e3fe9252
https://doi.org/10.1158/0008-5472.c.6499736.v1
https://doi.org/10.1158/0008-5472.c.6499736.v1
Autor:
Gregory David, Susan K. Logan, Nabeel Bardeesy, Rachel Ruoff, Patricia M. Finnerty, Rubén Fernández Rodríguez, Jessica Pellegrino, Teresa DiMauro, Petar Jelinic, Kathryn B. Grandinetti
Supplementary Figure Legends 1-7 from Sin3B Expression Is Required for Cellular Senescence and Is Up-regulated upon Oncogenic Stress
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::634eeebd754cc458c6e2ca66f2fd9cb1
https://doi.org/10.1158/0008-5472.22377689
https://doi.org/10.1158/0008-5472.22377689
Autor:
Susan K. Logan, Michael J. Garabedian, William L. Gerald, Myles Brown, Samir S. Taneja, S. Joseph Huang, Qianben Wang, Susan Ha, Rachel Ruoff, Paolo Mita, Jerome C. Nwachukwu
Supplementary Figure 1 from Genome-Wide Impact of Androgen Receptor Trapped clone-27 Loss on Androgen-Regulated Transcription in Prostate Cancer Cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f5a0211bf1e72bc5caa74446d6d01fd
https://doi.org/10.1158/0008-5472.22381034
https://doi.org/10.1158/0008-5472.22381034
Autor:
Susan K. Logan, Michael J. Garabedian, William L. Gerald, Myles Brown, Samir S. Taneja, S. Joseph Huang, Qianben Wang, Susan Ha, Rachel Ruoff, Paolo Mita, Jerome C. Nwachukwu
Supplementary Table 1B from Genome-Wide Impact of Androgen Receptor Trapped clone-27 Loss on Androgen-Regulated Transcription in Prostate Cancer Cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56748bfd5b7417c247ab8ee5de35d5c7
https://doi.org/10.1158/0008-5472.22381019
https://doi.org/10.1158/0008-5472.22381019
Autor:
Susan K. Logan, Michael J. Garabedian, William L. Gerald, Myles Brown, Samir S. Taneja, S. Joseph Huang, Qianben Wang, Susan Ha, Rachel Ruoff, Paolo Mita, Jerome C. Nwachukwu
Supplementary Figure 2 from Genome-Wide Impact of Androgen Receptor Trapped clone-27 Loss on Androgen-Regulated Transcription in Prostate Cancer Cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1df5527703b7cea58070fbdc79eea41d
https://doi.org/10.1158/0008-5472.22381031.v1
https://doi.org/10.1158/0008-5472.22381031.v1