Výsledky vyhledávání - "Rachel R. Smith"

Akademický článek

Review of the genus Chasmogenus Sharp, 1882 of northeastern South America with an emphasis on Venezuela, Suriname, and Guyana (Coleoptera, Hydrophilidae, Acidocerinae)

Autor: Rachel R. Smith, Andrew Edward Z. Short

Publikováno v: ZooKeys, Vol 934, Iss , Pp 25-79 (2020)

The water scavenger beetle genus Chasmogenus Sharp, 1882 is reviewed in northeastern South America using an integrative approach that combines adult morphology and molecular data from the gene cytochrome c oxidase I (COI). Eighteen new species are de

Externí odkaz: https://doaj.org/article/3474d7aea7ce40e68c6766650244eac6

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Akademický článek

ALLogeneic Heart STem Cells to Achieve Myocardial Regeneration (ALLSTAR) Trial: Rationale and Design

Autor: Tarun Chakravarty, Raj R. Makkar, Deborah D. Ascheim, Jay H. Traverse, Richard Schatz, Anthony Demaria, Gary S. Francis, Thomas J. Povsic, Rachel R. Smith, Joao A. Lima, Janice M. Pogoda, Linda Marbán, Timothy D. Henry

Publikováno v: Cell Transplantation, Vol 26 (2017)

Autologous cardiosphere-derived cells (CDCs) were the first therapeutic modality to demonstrate myocardial regeneration with a decrease in scar size and an increase in viable, functional tissue. Widespread applicability of autologous CDC therapy is l

Externí odkaz: https://doaj.org/article/d6cfed2aaf78453bb329b36743ddb0bb

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Akademický článek

Durable Benefits of Cellular Postconditioning: Long‐Term Effects of Allogeneic Cardiosphere‐Derived Cells Infused After Reperfusion in Pigs with Acute Myocardial Infarction

Autor: Hideaki Kanazawa, Eleni Tseliou, James F. Dawkins, Geoffrey De Couto, Romain Gallet, Konstantinos Malliaras, Kristine Yee, Michelle Kreke, Ileana Valle, Rachel R. Smith, Ryan C. Middleton, Chak‐Sum Ho, Rohan Dharmakumar, Debiao Li, Raj R. Makkar, Keiichi Fukuda, Linda Marbán, Eduardo Marbán

Publikováno v: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 5, Iss 2 (2016)

BackgroundInfusion of allogeneic cardiosphere‐derived cells (allo‐CDCs) postreperfusion elicits cardioprotective cellular postconditioning in pigs with acute myocardial infarction. However, the long‐term effects of allo‐CDCs have not been ass

Externí odkaz: https://doaj.org/article/66e5dab1634247818be04a3dfdc81abe

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Akademický článek

Y RNA fragment in extracellular vesicles confers cardioprotection via modulation of IL‐10 expression and secretion

Autor: Linda Cambier, Geoffrey de Couto, Ahmed Ibrahim, Antonio K Echavez, Jackelyn Valle, Weixin Liu, Michelle Kreke, Rachel R Smith, Linda Marbán, Eduardo Marbán

Publikováno v: EMBO Molecular Medicine, Vol 9, Iss 3, Pp 337-352 (2017)

Abstract Cardiosphere‐derived cells (CDCs) reduce myocardial infarct size via secreted extracellular vesicles (CDC‐EVs), including exosomes, which alter macrophage polarization. We questioned whether short non‐coding RNA species of unknown func

Externí odkaz: https://doaj.org/article/1565724645d04bdea2518be0a581c8fb

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Review of the genus Chasmogenus Sharp, 1882 of northeastern South America with an emphasis on Venezuela, Suriname, and Guyana (Coleoptera, Hydrophilidae, Acidocerinae)

Autor: Andrew E. Z. Short, Rachel R. Smith

Publikováno v: ZooKeys, Vol 934, Iss, Pp 25-79 (2020)
ZooKeys 934: 25-79

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b773dcd7795678ef1cff7888c298062a
https://doi.org/10.3897/zookeys.934.49359

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Augmenting canonical Wnt signalling in therapeutically inert cells converts them into therapeutically potent exosome factories

Autor: Russel Rogers, Linda Marbán, S. Vaturi, Ahmed G E Ibrahim, Brooke Tobin, Chang Li, Eduardo Marbán, Luis Rodriguez-Borlado, Lizbeth Sanchez, Mario Fournier, Travis J. Antes, Rachel R Smith, Akbarshakh Akhmerov, Liang Li, Moseley Jennifer J

Publikováno v: Nature biomedical engineering

Cardiosphere-derived cells (CDCs) are therapeutic candidates with disease-modifying bioactivity, but their variable potency has complicated their clinical translation. Transcriptomic analyses of CDCs from human donors have revealed that the therapeut

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fde4613bfa0d76a85250c0ebb0e4037
https://doi.org/10.1038/s41551-019-0448-6

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Cardiac and skeletal muscle effects in the randomized HOPE-Duchenne trial

Autor: Jeff Rudy, Janice M. Pogoda, Mohammad R. Ostovaneh, Joao A.C. Lima, Bharath Ambale-Venkatesh, Linda Marbán, Brian Fedor, Raj Makkar, James C. Fudge, Ronald G. Victor, John L. Jefferies, Deborah D. Ascheim, Michael D. Taylor, Bryan H. Goldstein, Rachel R Smith, Barry J. Byrne, Konstantinos Malliaras, Eduardo Marbán

Publikováno v: Neurology, vol 92, iss 8
Neurology

ObjectiveTo assess the feasibility, safety, and efficacy of intracoronary allogeneic cardiosphere-derived cells (CAP-1002) in patients with Duchenne muscular dystrophy (DMD).MethodsThe Halt Cardiomyopathy Progression (HOPE)-Duchenne trial is a phase

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e273b94c9362af34e41f12f025667aa2
https://doi.org/10.1212/wnl.0000000000006950

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The Impact of Angiotensin Converting Enzyme Inhibition and/or Angiotensin Receptor Blockade on Tissue Expression of the SARS‐CoV‐2 Receptor ACE2 in Mice

Autor: Steven C. Brooks, Aline S. Moreira, Ian Moore, Rachel R Smith, Hans Ackerman

Publikováno v: The FASEB Journal

The angiotensin‐converting enzyme 2 (ACE2) is an established receptor and entry point for the novel SARS‐CoV‐2 coronavirus, as the spike protein on the viral envelope binds the ACE2 receptor. Published histological profiling revealed ACE2 to be

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbc200cf1738497986887422912fc71b
https://doi.org/10.1096/fasebj.2021.35.s1.04584

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