Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Rachel Pettecrew"'
Autor:
C. A. Richard Boyd, Patrick D. Bailey, John. P. George, David Meredith, Richard A. Price, Keith M. Morgan, Ian D. Collier, Rachel Pettecrew, George L. Kellett
Publikováno v:
Chem. Commun.. :323-325
A quantitative method has been developed for determining the affinity of substrates for the peptide transporter PepT1, allowing oral availability of drugs via PepT1 to be estimated.
Autor:
John. G. George, David Meredith, Robin G. Pritchard, Rachel Pettecrew, Patrick D. Bailey, C. A. Richard Boyd, Richard A. Price, Keith M. Morgan, Ian D. Collier, George L. Kellett
Publikováno v:
Chemical communications (Cambridge, England). (42)
The conformation at the first residue of dipeptide substrates for the peptide transporter PepT1 has been probed using constrained peptide analogues, and the active conformation has been identified.
There have been several major developments in the synthesis of amides since COFGT (1995). First has been the superseding (after several decades) of diimides as the main coupling reagent for amines to carboxylic acids, especially in the synthesis of p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a6dbb970e19c6f62a1e3d549c95bf200
https://doi.org/10.1016/b0-08-044655-8/00096-9
https://doi.org/10.1016/b0-08-044655-8/00096-9
Autor:
Stephen Miles, Richard D. Price, David Meredith, Patrick D. Bailey, Myrtani Pieri, David W. Foley, Ho Kam Lam, Rachel Pettecrew
Publikováno v:
Organic & Biomolecular Chemistry. 7:3652
A thiodipeptide carrier system is shown to be effective at enabling a range of covalently bound molecules, including benzyl, benzoyl and ibuprofen conjugates, to be transported via the intestinal peptide transporter PepT1, demonstrating its potential
Autor:
Patrick D. Bailey, David Meredith, C. A. Richard Boyd, Keith M. Morgan, Ian D. Collier, Rachel Pettecrew, Richard A. Price, George L. Kellett
Publikováno v:
Organic & Biomolecular Chemistry. 3:4038
The stereochemistry of thiodipeptides of proline [e.g. Ala-Psi[CS-N]-Pro] can be controlled using pH, allowing the trans-preference for substrates of the peptide transporter PepT1 to be confirmed.
Autor:
Patrick D. Bailey, C. A. Richard Boyd, Ian D. CollierIn memory of Ian Collier (1960–2002)., John. P. George, George L. Kellett, David Meredith, Keith M. Morgan, Rachel Pettecrew, Richard A. Price
Publikováno v:
Chemical Communications; Jan2006, Vol. 2006 Issue 3, p323-325, 3p