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pro vyhledávání: '"Rachel P. Gaither"'
Autor:
Emma L. Baar, Amanda W. Hutchins, Rachel P. Gaither, Yetis Gultekin, Dudley W. Lamming, Ömer H. Yilmaz, Pekka Katajisto, Maria M. Mihaylova, David M. Sabatini
Publikováno v:
Aging Cell
Wiley Blackwell
Wiley Blackwell
Rapamycin, an inhibitor of the mechanistic target of rapamycin (mTOR), robustly extends the lifespan of model organisms including mice. We recently found that chronic treatment with rapamycin not only inhibits mTOR complex 1 (mTORC1), the canonical t