Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Rachel P L Van Swelm"'
Autor:
Robert Staroń, Paweł Lipiński, Małgorzata Lenartowicz, Aleksandra Bednarz, Anna Gajowiak, Ewa Smuda, Wojciech Krzeptowski, Marek Pieszka, Tamara Korolonek, Iqbal Hamza, Dorine W Swinkels, Rachel P L Van Swelm, Rafał R Starzyński
Publikováno v:
PLoS ONE, Vol 12, Iss 7, p e0181117 (2017)
Heme is an efficient source of iron in the diet, and heme preparations are used to prevent and cure iron deficiency anemia in humans and animals. However, the molecular mechanisms responsible for heme absorption remain only partially characterized. H
Externí odkaz:
https://doaj.org/article/0406546ec3174bfd9b13a8984aacb319
Autor:
Robert Staroń, Rachel P L Van Swelm, Paweł Lipiński, Anna Gajowiak, Małgorzata Lenartowicz, Aleksandra Bednarz, Małgorzata Gajewska, Marek Pieszka, Coby M M Laarakkers, Dorine W Swinkels, Rafał R Starzyński
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0136695 (2015)
Among livestock, domestic pig (Sus scrofa) is a species, in which iron metabolism has been most intensively examined during last decade. The obvious reason for studying the regulation of iron homeostasis especially in young pigs is neonatal iron defi
Externí odkaz:
https://doaj.org/article/bd381ffd2c054f3ea3e406d8a06cecde
Autor:
Rachel P L van Swelm, Coby M M Laarakkers, Ellen C van der Kuur, Eva Morava-Kozicz, Ron A Wevers, Kevin D Augustijn, Daan J Touw, Maro H Sandel, Rosalinde Masereeuw, Frans G M Russel
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e49524 (2012)
Drug-induced liver injury (DILI) is the leading cause of acute liver failure. Currently, no adequate predictive biomarkers for DILI are available. This study describes a translational approach using proteomic profiling for the identification of urina
Externí odkaz:
https://doaj.org/article/e72eb2e6d83c4354b2efc7eb581a84fb
Autor:
Harold Tjalsma, Coby M M Laarakkers, Rachel P L van Swelm, Milan Theurl, Igor Theurl, Erwin H Kemna, Yuri E M van der Burgt, Hanka Venselaar, Bas E Dutilh, Frans G M Russel, Günter Weiss, Rosalinde Masereeuw, Robert E Fleming, Dorine W Swinkels
Publikováno v:
PLoS ONE, Vol 6, Iss 3, p e16762 (2011)
The mouse is a valuable model for unravelling the role of hepcidin in iron homeostasis, however, such studies still report hepcidin mRNA levels as a surrogate marker for bioactive hepcidin in its pivotal function to block ferroportin-mediated iron tr
Externí odkaz:
https://doaj.org/article/3ed65de1b8834ba2bf4efc8df56a6788
Autor:
Rachel P. L. van Swelm, Sanne Beurskens, Henry Dijkman, Erwin T. G. Wiegerinck, Rian Roelofs, Frank Thévenod, Johan van der Vlag, Jack F. M. Wetzels, Dorine W. Swinkels, Bart Smeets
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract Kidney iron deposition may play a role in the progression of tubulointerstitial injury during chronic kidney disease. Here, we studied the molecular mechanisms of kidney iron loading in experimental focal segmental glomerulosclerosis (FSGS)
Externí odkaz:
https://doaj.org/article/aa89f4d3a9384e2299ca2096925f5c50
Autor:
Rachel P. L. van Swelm, Frank Thévenod, Natascha A. Wolff, Bettina Scharner, Stephanie Probst, Wing-Kee Lee, Eleni Roussa, Johannes Fels
Publikováno v:
Archives of Toxicology, 95, 2719-2735
Archives of Toxicology
Archives of Toxicology, 95, 8, pp. 2719-2735
Archives of Toxicology
Archives of Toxicology, 95, 8, pp. 2719-2735
The liver hormone hepcidin regulates systemic iron homeostasis. Hepcidin is also expressed by the kidney, but exclusively in distal nephron segments. Several studies suggest hepcidin protects against kidney damage involving Fe2+ overload. The nephrot
Autor:
Alannah K A McKay, Jamie Whitfield, Rachel P. L. van Swelm, Megan L. Ross, Ida A. Heikura, Nicolin Tee, Marijke Welveart, Peter Peeling, Coby M. Laarakkers, Avish P. Sharma, David B. Pyne, Louise M. Burke
Publikováno v:
International Journal of Sport Nutrition and Exercise Metabolism, 31, 101-108
International Journal of Sport Nutrition and Exercise Metabolism, 31, 2, pp. 101-108
International Journal of Sport Nutrition and Exercise Metabolism, 31, 2, pp. 101-108
This study implemented a 2-week high carbohydrate (CHO) diet intended to maximize CHO oxidation rates and examined the iron-regulatory response to a 26-km race walking effort. Twenty international-level, male race walkers were assigned to either a no
Autor:
Laura E. Diepeveen, Gaby Stegemann, Erwin T. Wiegerinck, Rian Roelofs, Myrthe Naber, Olivier Lóreal, Bart Smeets, Frank Thévenod, Dorine W. Swinkels, Rachel P. L. van Swelm
Publikováno v:
International Journal of Molecular Sciences, 23, 3
International Journal of Molecular Sciences, Vol 23, Iss 1352, p 1352 (2022)
International Journal of Molecular Sciences, 23
International Journal of Molecular Sciences; Volume 23; Issue 3; Pages: 1352
International Journal of Molecular Sciences
International Journal of Molecular Sciences, 2022, 23 (3), pp.1352. ⟨10.3390/ijms23031352⟩
International Journal of Molecular Sciences, Vol 23, Iss 1352, p 1352 (2022)
International Journal of Molecular Sciences, 23
International Journal of Molecular Sciences; Volume 23; Issue 3; Pages: 1352
International Journal of Molecular Sciences
International Journal of Molecular Sciences, 2022, 23 (3), pp.1352. ⟨10.3390/ijms23031352⟩
International audience; Hemolysis is known to cause acute kidney injury (AKI). The iron regulatory hormone hepcidin, produced by renal distal tubules, is suggested to exert a renoprotective role during this pathology. We aimed to elucidate the molecu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::880845d6907b10e261abf9e802ff0600
https://doi.org/10.3390/ijms23031352
https://doi.org/10.3390/ijms23031352
Autor:
Annalisa Castagna, Gordana Olbina, Marianne Fillet, Rachel P. L. van Swelm, Marta E Pawlak, Dorine W. Swinkels, Kelly R Pitts, Vincent Delatour, Coby M. Laarakkers, Anton F.J. de Haan, Mark Westerman, Anneke Geurts-Moespot, Laura E. Diepeveen, Thibaud Lefebvre, Fatih F Uğuz, Matthias Herkert, Kim E S A Verberne, Siem M. Klaver, Ioana M. Abbas, Sukhvinder S. Bansal, Outi Itkonen, Cas Weykamp, Gustavo Martos, Domenico Girelli, Naohisa Tomosugi
Publikováno v:
Clinical Chemistry and Laboratory Medicine, 57, 6, pp. 864-872
Clinical Chemistry and Laboratory Medicine, 57, 864-872
Clinical Chemistry and Laboratory Medicine, 57, 864-872
Background Hepcidin concentrations measured by various methods differ considerably, complicating interpretation. Here, a previously identified plasma-based candidate secondary reference material (csRM) was modified into a serum-based two-leveled sRM.
Autor:
Coby M. Laarakkers, M. Claire Woltering, Mirjam Vreugdenhil, Boudewijn Bakker, Marjolijn D. Akkermans, Dick Mul, Rachel P. L. van Swelm, Daniëlle C M van der Kaay, Euphemia C. A. M. Houdijk, Frank Brus, Martine C. de Vries, Agnes Clement-de Boers, Johannes B. van Goudoever
Publikováno v:
Pediatric Hematology and Oncology, 38, 108-123
Pediatric hematology and oncology, 38(2), 108-123. Informa Healthcare
Pediatric Hematology and Oncology, 38, 2, pp. 108-123
Pediatric hematology and oncology, 38(2), 108-123. Informa Healthcare
Pediatric Hematology and Oncology, 38, 2, pp. 108-123
Chronic low-grade inflammation in type 1 diabetes (T1D) might increase hepcidin synthesis, possibly resulting in functional iron deficiency (FID). We hypothesized that in T1D children with FID, hepcidin concentrations are increased compared to those
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a01edfb51f8750299928725d4f82f69
http://hdl.handle.net/2066/235802
http://hdl.handle.net/2066/235802