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pro vyhledávání: '"Rachel Melendez"'
Autor:
M. Violet Lee, Ola M. Saad, Sylvia Wong, Jason LaMar, Lynn Kamen, Ben Ordonia, Rachel Melendez, Azadeh Hassanzadeh, Shan Chung, Surinder Kaur
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Major histocompatibility complex (MHC)-Associated Peptide Proteomics (MAPPs) is an ex vivo method used to assess the immunogenicity risk of biotherapeutics. MAPPs can identify potential T-cell epitopes within the biotherapeutic molecule. Using adalim
Externí odkaz:
https://doaj.org/article/0bd769f29dfe4b1888748f001e7e2a9e
Autor:
Rachel Melendez, Benjamin Ordonia, Joyce Guerrero, Azadeh Hassanzadeh, Peter Tran, Justin Low, Manda Wong, Jochen Brumm, Shan Chung, Lynn Kamen
Publikováno v:
Bioanalysis. 14:703-713
Aim: Immunogenicity risk assessment assays are powerful tools that assess the relative immunogenicity of potential biotherapeutics. We detail here the development of a novel assay that measures the degree of antibody internalization by antigen-presen
Autor:
Christopher Lowe, Mike Reichelt, Shilpi Mahajan, Trung Nguy, Rachel Melendez, Jenny Yang, Yijin Li, Vicki Plaks, Kathryn E. Yoh, Rebecca Suttmann, Wenfeng Xu, Jane Ruppel, Luciana Molinero
Publikováno v:
Journal of immunological methods. 490
Extracellular vesicles (EVs) are gaining considerable traction within the liquid biopsy arena, as carriers of information from cells in distant sites that may not be accessible for biopsy. Therefore, there is a need to develop methods to enrich for s