Výsledky vyhledávání - "Rachel M. Zunder"

Generation of a UsefulroX1Allele by Targeted Gene Conversion

Autor: Barbara P. Rattner, Richard L. Kelley, Victoria H. Meller, Victoria A. Moran, Kathryn Hughes Barry, Manasi S. Apte, Rachel M. Zunder, Debashish U. Menon

Publikováno v: G3: Genes|Genomes|Genetics

Methods for altering the sequence of endogenous Drosophila melanogaster genes remain labor-intensive. We have tested a relatively simple strategy that enables the introduction of engineered mutations in the vicinity of existing P-elements. This metho

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b58286fc59eddd24d2d32646ba796e48
https://doi.org/10.1534/g3.113.008508

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Direct Interplay among Histones, Histone Chaperones, and a Chromatin Boundary Protein in the Control of Histone Gene Expression

Autor: Rachel M. Zunder, Jasper Rine

In Saccharomyces cerevisiae, the histone chaperone Rtt106 binds newly synthesized histone proteins and mediates their delivery into chromatin during transcription, replication, and silencing. Rtt106 is also recruited to histone gene regulatory region

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bb1adf28bff0a66ffe701d5d59fd807
https://europepmc.org/articles/PMC3486138/

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Two surfaces on the histone chaperone Rtt106 mediate histone binding, replication, and silencing

Autor: Andrew J. Antczak, James M. Berger, Rachel M. Zunder, Jasper Rine

Publikováno v: Proceedings of the National Academy of Sciences. 109

The histone chaperone Rtt106 binds histone H3 acetylated at lysine 56 (H3K56ac) and facilitates nucleosome assembly during several molecular processes. Both the structural basis of this modification-specific recognition and how this recognition infor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58778fdfafdac88f4e6f57100e448569
https://doi.org/10.1073/pnas.1119095109

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Double-Strand Break Repair Pathways Protect against CAG/CTG Repeat Expansions, Contractions and Repeat-Mediated Chromosomal Fragility in Saccharomyces cerevisiae

Autor: Lionel Gellon, Rachel M. Zunder, Catherine H. Freudenreich, Rangapriya Sundararajan

Trinucleotide repeats can form secondary structures, whose inappropriate repair or replication can lead to repeat expansions. There are multiple loci within the human genome where expansion of trinucleotide repeats leads to disease. Although it is kn

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b45656ffde6e1fa8f6f5ccc6e67879d
https://europepmc.org/articles/PMC2815931/

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