Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Rachel M. Hurley"'
Autor:
Ann L. Oberg, Ethan P. Heinzen, Xiaonan Hou, Mariam M. Al Hilli, Rachel M. Hurley, Andrea E. Wahner Hendrickson, Krista M. Goergen, Melissa C. Larson, Marc A. Becker, Jeanette E. Eckel-Passow, Matthew J. Maurer, Scott H. Kaufmann, Paul Haluska, S. John Weroha
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract Repeated measures studies are frequently performed in patient-derived xenograft (PDX) models to evaluate drug activity or compare effectiveness of cancer treatment regimens. Linear mixed effects regression models were used to perform statist
Externí odkaz:
https://doaj.org/article/ff6b9ed53489469fac350642c746a06e
Autor:
Clare L. Scott, Matthew J. Wakefield, Alexander Dobrovic, Scott H. Kaufmann, Nicola Waddell, Katia Nones, S. John Weroha, Elizabeth M. Swisher, David D.L. Bowtell, Anna DeFazio, Australian Ovarian Cancer Study, Nadia Traficante, Orla McNally, Inger Olesen, Damien Kee, Maria I. Harrell, Mohammad Reza Eftekhariyan Ghamsari, Zi Qing Chai, Ashan Musafer, Marc Radke, Kristy Shield-Artin, Nirashaa Bound, Genevieve Dall, Elizabeth Lieschke, Gwo-Yaw Ho, Cassandra J. Vandenberg, Cordelia D. McGehee, Rachel M. Hurley, Olga Kondrashova, Ksenija Nesic
In high-grade serous ovarian carcinoma (HGSC), deleterious mutations in DNA repair gene RAD51C are established drivers of defective homologous recombination and are emerging biomarkers of PARP inhibitor (PARPi) sensitivity. RAD51C promoter methylatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e56ea8d4ae85dde3e5f8a4e6285a8fd
https://doi.org/10.1158/0008-5472.c.6513498
https://doi.org/10.1158/0008-5472.c.6513498
Autor:
Clare L. Scott, Matthew J. Wakefield, Alexander Dobrovic, Scott H. Kaufmann, Nicola Waddell, Katia Nones, S. John Weroha, Elizabeth M. Swisher, David D.L. Bowtell, Anna DeFazio, Australian Ovarian Cancer Study, Nadia Traficante, Orla McNally, Inger Olesen, Damien Kee, Maria I. Harrell, Mohammad Reza Eftekhariyan Ghamsari, Zi Qing Chai, Ashan Musafer, Marc Radke, Kristy Shield-Artin, Nirashaa Bound, Genevieve Dall, Elizabeth Lieschke, Gwo-Yaw Ho, Cassandra J. Vandenberg, Cordelia D. McGehee, Rachel M. Hurley, Olga Kondrashova, Ksenija Nesic
All Supplementary Methods for the manuscript
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72057a47e3c29c834e15f851c84579c8
https://doi.org/10.1158/0008-5472.22429956
https://doi.org/10.1158/0008-5472.22429956
Autor:
Clare L. Scott, Matthew J. Wakefield, Alexander Dobrovic, Scott H. Kaufmann, Nicola Waddell, Katia Nones, S. John Weroha, Elizabeth M. Swisher, David D.L. Bowtell, Anna DeFazio, Australian Ovarian Cancer Study, Nadia Traficante, Orla McNally, Inger Olesen, Damien Kee, Maria I. Harrell, Mohammad Reza Eftekhariyan Ghamsari, Zi Qing Chai, Ashan Musafer, Marc Radke, Kristy Shield-Artin, Nirashaa Bound, Genevieve Dall, Elizabeth Lieschke, Gwo-Yaw Ho, Cassandra J. Vandenberg, Cordelia D. McGehee, Rachel M. Hurley, Olga Kondrashova, Ksenija Nesic
All supplementary tables for the manuscript
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9978f21b18492658a866a239188bd868
https://doi.org/10.1158/0008-5472.22429950
https://doi.org/10.1158/0008-5472.22429950
Autor:
Clare L. Scott, Matthew J. Wakefield, Alexander Dobrovic, Scott H. Kaufmann, Nicola Waddell, Katia Nones, S. John Weroha, Elizabeth M. Swisher, David D.L. Bowtell, Anna DeFazio, Australian Ovarian Cancer Study, Nadia Traficante, Orla McNally, Inger Olesen, Damien Kee, Maria I. Harrell, Mohammad Reza Eftekhariyan Ghamsari, Zi Qing Chai, Ashan Musafer, Marc Radke, Kristy Shield-Artin, Nirashaa Bound, Genevieve Dall, Elizabeth Lieschke, Gwo-Yaw Ho, Cassandra J. Vandenberg, Cordelia D. McGehee, Rachel M. Hurley, Olga Kondrashova, Ksenija Nesic
All supplementary figures for the manuscript
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64220fae7fa95d48dedecbd1398a6415
https://doi.org/10.1158/0008-5472.22429959
https://doi.org/10.1158/0008-5472.22429959
Autor:
Mark A. McNiven, Baoan Ji, Martin E. Fernandez-Zapico, Luciana L. Almada, Rachel M. Hurley, Arthur C. Sletten, Christopher Magnine, Gina L. Razidlo
Supplementary Figures 1-5. Supplementary Figure 1. Vav1 is expressed in a subset of tumor cell lines. Supplementary Figure 2. Azathioprine does not inhibit migration by pancreatic tumor cells. Supplementary Figure 3. Vav1 is expressed in tumors from
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af2fc760b9de2018091d63ac60bda674
https://doi.org/10.1158/0008-5472.22405406.v1
https://doi.org/10.1158/0008-5472.22405406.v1
Autor:
Mohammad Reza Eftekhariyan Ghamsari, Nadia Traficante, Nirashaa Bound, Cordelia D. McGehee, Inger Olesen, Kristy Shield-Artin, Clare L. Scott, Elizabeth Lieschke, Rachel M. Hurley, Anna deFazio, Ashan Musafer, Nicola Waddell, Marc R. Radke, Matthew Wakefield, Alexander Dobrovic, Ksenija Nesic, Genevieve Dall, Maria I. Harrell, Olga Kondrashova, Damien Kee, S. John Weroha, Scott H. Kaufmann, Katia Nones, David D.L. Bowtell, Cassandra J. Vandenberg, Orla McNally, Elizabeth M. Swisher, Gwo-Yaw Ho, Zi Qing Chai
Publikováno v:
Cancer Research. 81:4709-4722
In high-grade serous ovarian carcinoma (HGSC), deleterious mutations in DNA repair gene RAD51C are established drivers of defective homologous recombination and are emerging biomarkers of PARP inhibitor (PARPi) sensitivity. RAD51C promoter methylatio
Autor:
Andrea E. Wahner Hendrickson, Ksenija Nesic, Hu Li, Xiaonan Hou, Rebecca L. Kelly, Thomas Harding, Clare L. Scott, Rachel M. Hurley, Paula A. Schneider, Melissa C. Southey, Matthew Wakefield, Karen S. Flatten, Jill M. Wagner, Larry M. Karnitz, Christian A. Ross, Cordelia D. McGehee, Alexander Dobrovic, Taylor M. Weiskittel, Paul Haluska, Scott H. Kaufmann, S. John Weroha, Annapoorna Venkatachalam, Cristina Correia, Marc A. Becker, Marc R. Radke, Kevin K. Lin, Kevin L. Peterson, X. Wei Meng, Nicholas M. Pathoulas, Elizabeth M. Swisher, Ee Ming Wong, Olga Kondrashova, Iain A. McNeish
Publikováno v:
NAR Cancer. 3
Acquired PARP inhibitor (PARPi) resistance in BRCA1- or BRCA2-mutant ovarian cancer often results from secondary mutations that restore expression of functional protein. RAD51C is a less commonly studied ovarian cancer susceptibility gene whose promo
Publikováno v:
Journal of Palliative Medicine. 22:977-980
Background: Chemotherapy-induced peripheral neuropathy is characterized by pain, numbness, and tingling in the hands and feet and by diminished quality of life. Multiple previous studies, ...
Autor:
Annapoorna Venkatachalam, Kevin L. Peterson, Cristina Correia, Karen S. Flatten, Xianon Hou, Paula A. Schneider, Emily Balczewski, Cordelia McGehee, Rachel M. Hurley, Xue W. Meng, Chance Sine, Rameen Shah, Nicole Vincelettte, Husheng Ding, Hu Li, Saravut (John) Weroha, Scott H. Kaufmann
Publikováno v:
Cancer Research. 82:1832-1832
Background: The kinases ataxia-telangiectasia-mutated-and-Rad3-related (ATR), checkpoint kinase 1 (CHK1) and WEE1 participate in the response to replication stress. Inhibitors of ATR, WEE1 and CHK1 are being tested for antineoplastic activity as mono