Zobrazeno 1 - 2
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pro vyhledávání: '"Rachel M. Golden"'
Autor:
Joanna Klapacz, Richard C. Pleus, Matthew J. LeBaron, Lisa M. Corey, Robert A. Budinsky, James Crissman, Rachel M. Golden, Mark Lafranconi
Publikováno v:
Regulatory toxicology and pharmacology : RTP. 119
Studies demonstrate that with sufficient dose and duration, 1,4-dioxane (1,4-DX) induces liver tumors in laboratory rodent models. The available evidence aligns with a threshold-dependent, tumor promotion mode of action (MOA). The MOA and key events
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::745bf5f74f7bf096d00ffc0fc5be03b8
https://pubmed.ncbi.nlm.nih.gov/33189748
https://pubmed.ncbi.nlm.nih.gov/33189748
Publikováno v:
Food and Chemical Toxicology. 110:200-203
Typically, when a protein is orally toxic, it acts via acute mechanisms, especially at high doses. Therefore, an acute oral toxicity study is considered appropriate for evaluating the safety of transgenic proteins. Soybean plants (events DAS-68416-4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d096c7c9def1cd4e0deb64a0f92d50c8
https://doi.org/10.1016/j.fct.2017.10.036
https://doi.org/10.1016/j.fct.2017.10.036