Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Rachel M. Gillard"'
Publikováno v:
J Am Chem Soc
A powerful tris(4-bromophenyl)aminium hexachloroantimonate (BAHA) mediated regioselective intermolecular coupling reaction of vindoline with a wide range of substrates that include β-ketoesters, β-diketones, β-ketoaldehydes, β-ketonitriles, β-ke
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a58b69269d09059445dc1cc257c7e6cd
https://doi.org/10.1021/jacs.1c10971
https://doi.org/10.1021/jacs.1c10971
Autor:
Dale L. Boger, Rachel M. Gillard, Jiajun Zhang, Richard Steel, Jocelyn Wang, Jessica L. Strull, Bin Cai, Nilanjana Chakraborty
Publikováno v:
Synthesis.
Retrosynthetic deconstruction of a core aromatic ring is an especially simplifying retrosynthetic step, reducing the complexity of the precursor synthetic target. Moreover, when implemented to provide a penultimate intermediate, it enables late-stage
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5f1c1a7c40d36203d05f94910920def1
https://doi.org/10.1055/a-1959-2088
https://doi.org/10.1055/a-1959-2088
Publikováno v:
ACS Catalysis. 10:11791-11796
An approach to the α,β-unsaturated acyl azolium has been developed that exploits N-heterocyclic carbenes (NHCs) and acyl fluorides, without additional oxidants, bases, or preactivated pro-nucleophi...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0b231005ce569cfa0e8fd2178260140e
https://doi.org/10.1021/acscatal.0c02705
https://doi.org/10.1021/acscatal.0c02705
Publikováno v:
Angewandte Chemie. 131:13504-13508
While the enantioselective Rauhut-Currier reaction is established with bis(enone) substrates, it is yet to be reported with less electrophilic bis(enoate) substrates. By exploiting high-nucleophilicity N-heterocyclic carbenes, it is possible to achie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15f0578b8ce92363eb1fb1713d67052c
https://doi.org/10.1002/ange.201907111
https://doi.org/10.1002/ange.201907111
Autor:
Margaret A. Brimble, Rachel M. Gillard
Publikováno v:
Organic & Biomolecular Chemistry. 17:8272-8307
The spiroketal moiety is an important privileged scaffold that occurs extensively in natural products, drugs, and bioactive molecules. Naturally occurring spiroketals are numerous, however aryl-fused spiroketals are relatively rare. The only comprehe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4c6153313479d52f274f8fdf74b36fe
https://doi.org/10.1039/c9ob01598a
https://doi.org/10.1039/c9ob01598a
Publikováno v:
Israel Journal of Chemistry. 56:522-530
Donor-acceptor cyclopropanes are known to serve as dipole precursors capable of engaging in (3+2) annulations with electron-deficient π-systems. In 2013, the reaction of donor-acceptor cyclopropanes with α,β-unsaturated acyl fluorides in an all-ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9250aa306c0aef63fe9aa3f5d962d1c2
https://doi.org/10.1002/ijch.201500102
https://doi.org/10.1002/ijch.201500102
Autor:
Rachel M. Gillard, Jonathan Sperry
Publikováno v:
The Journal of Organic Chemistry. 80:2900-2906
A series of 2-(3'-indolyl)tetrahydrofurans have been prepared by a DDQ-mediated oxidative cycloetherification process. Performing the reaction under biphasic conditions prevents reductive cleavage of the products by the spent oxidant (DDQH2).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::060732ec4983dbbceccc66d7bb827cd7
https://doi.org/10.1021/acs.joc.5b00112
https://doi.org/10.1021/acs.joc.5b00112
Publikováno v:
Angewandte Chemie (International ed. in English). 57(17)
Herein we report the enantioselective N-heterocyclic carbene catalyzed (4+2) annulation of the dienyl acyl azolium with enolates. The reaction exploits readily accessible acyl fluorides and TMS enol ethers to give a range of highly enantio- and diast
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::476d29e3c0325aa606126d61a831a48e
https://pubmed.ncbi.nlm.nih.gov/29380549
https://pubmed.ncbi.nlm.nih.gov/29380549
Publikováno v:
ChemInform. 47
Donor-acceptor cyclopropanes are known to serve as dipole precursors capable of engaging in (3+2) annulations with electron-deficient π-systems. In 2013, the reaction of donor-acceptor cyclopropanes with α,β-unsaturated acyl fluorides in an all-ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d2da11f176678c87574b70c4d1a284c7
https://doi.org/10.1002/chin.201636239
https://doi.org/10.1002/chin.201636239
Autor:
Jonathan Sperry, Rachel M. Gillard
Publikováno v:
ChemInform. 46
A series of 2-(3′-indolyl)tetrahydrofurans have been prepared by a DDQ-mediated oxidative cycloetherification process. Performing the reaction under biphasic conditions prevents reductive cleavage of the products by the spent oxidant (DDQH2).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c67f4d2e7cc03b7732f3e94565b9db58
https://doi.org/10.1002/chin.201530158
https://doi.org/10.1002/chin.201530158