Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Rachel M. Gibbons Johnson"'
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
The programmed death-1 (PD-1) and its ligand PD-L1 (B7-H1) signaling pathway has been the focus of much enthusiasm in the fields of tumor immunology and oncology with recent FDA approval of the anti-PD-1 antibodies pembrolizumab and nivolumab and the
Externí odkaz:
https://doaj.org/article/103b9355f77c4ec4a15437063439fa4a
Publikováno v:
Journal of Immunology Research, Vol 2017 (2017)
Tumor cells are capable of limiting antitumor CD8+ T cell responses through their cell surface expression of PD-L1. In addition to PD-1 expressed by CD8+ T cells, PD-L1 also binds to CD80 expressed by CD8+ T cells. The influence of the PD-L1/CD80 int
Externí odkaz:
https://doaj.org/article/15bf37ccd45647e38cfb4663b01511a8
Publikováno v:
Journal of Medicinal Food. 22:1146-1150
Echinacea purpurea is a common herbal remedy used to treat a variety of illnesses, though its health benefits and effects on the immune system have not been fully elucidated. In this study...
Autor:
Rachel M. Gibbons Johnson, Elizabeth A. Van Orsow, Jerome Ritz, David H. McKenna, Julianne Connors, Allison Hubel, Adam Joules, Sarah Nikiforow, Adrian P. Gee
Publikováno v:
Cytotherapy
Background aims Cell therapies are an emerging treatment option for a variety of diseases, especially with the success of chimeric antigen receptor T-cell therapies. With 18 FDA-approved cell therapy products as of December 2020 and a growing number
Autor:
Scott M. Dehm, Michael D. Nyquist, Daniel F. Voytas, Jamie L. Van Etten, Rendong Yang, Olivia Ondigi, Yeung Ho, Christine Henzler, Yingming Li, Rachel M. Gibbons Johnson
Publikováno v:
Cancer Research. 77:5228-5235
Prostate cancer is the second leading cause of male cancer deaths due to disease progression to castration-resistant prostate cancer (CRPC). Androgen receptor (AR) splice variants including AR-V7 function as constitutively active transcription factor
Publikováno v:
Nature Immunology. 21:365-366
PD-L1 expressed by T cells provides backward and forward signals to restrain both innate and adaptive immune responses in tumor tissues.
Publikováno v:
Cytotherapy
In the unique supply chain of cellular therapies, preservation is important to keep the cell product viable. Many factors in cryopreservation affect the outcome of a cell therapy: (i) formulation and introduction of a freezing medium, (ii) cooling ra
Autor:
Larissa A Minicucci, Leslie C. Sharkey, Emily Walz, Kristi Flynn, Kayla Sample, Rachel M. Gibbons Johnson
Publikováno v:
Journal of the American Veterinary Medical Association. 250:612-614
Publikováno v:
Journal of Immunology Research, Vol 2017 (2017)
Journal of Immunology Research
Journal of Immunology Research
Tumor cells are capable of limiting antitumor CD8+ T cell responses through their cell surface expression of PD-L1. In addition to PD-1 expressed by CD8+ T cells, PD-L1 also binds to CD80 expressed by CD8+ T cells. The influence of the PD-L1/CD80 int