Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Rachel M. Cronin"'
Autor:
Bradley S. Jones, Daniel D. Hu, Kathleen R. Nicholson, Rachel M. Cronin, Simon D. Weaver, Matthew M. Champion, Patricia A. Champion
Publikováno v:
mSphere, Vol 9, Iss 5 (2024)
ABSTRACT The mycobacterial cell envelope is a major virulence determinant in pathogenic mycobacteria. Specific outer lipids play roles in pathogenesis, modulating the immune system and promoting the secretion of virulence factors. ESX-1 (ESAT-6 syste
Externí odkaz:
https://doaj.org/article/63c1e0bddc6843a287d8a6f4cb68bdb7
Autor:
Kathleen R. Nicholson, Rachel M. Cronin, Rebecca J. Prest, Aruna R. Menon, Yuwei Yang, Madeleine K. Jennisch, Matthew M. Champion, David M. Tobin, Patricia A. Champion
Publikováno v:
mBio, Vol 15, Iss 4 (2024)
ABSTRACTBacterial pathogens use protein secretion systems to transport virulence factors and regulate gene expression. Among pathogenic mycobacteria, including Mycobacterium tuberculosis and Mycobacterium marinum, the ESAT-6 system 1 (ESX-1) secretio
Externí odkaz:
https://doaj.org/article/98c5e246555a43a18ff67290f38d2e86
Autor:
Kathleen R. Nicholson, Rachel M. Cronin, Aruna R. Menon, Madeleine K. Jennisch, David M. Tobin, Patricia A. Champion
Publikováno v:
bioRxiv
Bacterial pathogens use protein secretion systems to translocate virulence factors into the host and to control bacterial gene expression. The ESX-1 (ESAT-6 system 1) secretion system facilitates disruption of the macrophage phagosome during infectio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0be6350a29983cb99cce050ce4e1bc5
https://doi.org/10.1101/2023.02.15.528779
https://doi.org/10.1101/2023.02.15.528779
Autor:
Joseph W. Saelens, Mollie I. Sweeney, Gopinath Viswanathan, Ana María Xet-Mull, Kristen L. Jurcic Smith, Dana M. Sisk, Daniel D. Hu, Rachel M. Cronin, Erika J. Hughes, W. Jared Brewer, Jörn Coers, Matthew M. Champion, Patricia A. Champion, Craig B. Lowe, Clare M. Smith, Sunhee Lee, Jason E. Stout, David M. Tobin
Publikováno v:
Cell
The human pathogen Mycobacterium tuberculosis typically causes lung disease but can also disseminate to other tissues. We identified a M. tuberculosis (Mtb) outbreak presenting with unusually high rates of extrapulmonary dissemination and bone diseas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83917a2f0a20514c1f17e7753d9b41f9
https://europepmc.org/articles/PMC9691622/
https://europepmc.org/articles/PMC9691622/
Autor:
Rachel M, Cronin, Micah J, Ferrell, Clare W, Cahir, Matthew M, Champion, Patricia A, Champion
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 119(24)
The ESX-1 (ESAT-6-system-1) system and the protein substrates it transports are essential for mycobacterial pathogenesis. The precise ways that ESX-1 substrates contribute to virulence remains unknown. Several known ESX-1 substrates are also required
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::acba743e2744918c9c675f00dc782f07
https://pubmed.ncbi.nlm.nih.gov/35671426
https://pubmed.ncbi.nlm.nih.gov/35671426
Publikováno v:
J Bacteriol
Chemotaxis and motility are important traits that support bacterial survival in various ecological niches and in pathogenic and symbiotic host interaction. Chemotactic stimuli are sensed by chemoreceptors or methyl-accepting chemotaxis proteins (MCPs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91d11c0d5478f36dfe4525a06a33ce25
https://pubmed.ncbi.nlm.nih.gov/32571966
https://pubmed.ncbi.nlm.nih.gov/32571966