Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Rachel M Torrez"'
Publikováno v:
eLife, Vol 7 (2018)
Double-stranded DNA (dsDNA) binding and cleavage by Cas9 is a hallmark of type II CRISPR-Cas bacterial adaptive immunity. All known Cas9 enzymes are thought to recognize DNA exclusively as a natural substrate, providing protection against DNA phage a
Externí odkaz:
https://doaj.org/article/be2099c4da4e42ada9d10a9af4a3c937
Publikováno v:
Biochemistry. 62:1-16
The RNase III endoribonuclease Dicer was discovered to be associated with cleavage of double-stranded RNA in 2001. Since then, many advances in our understanding of Dicer function have revealed that the enzyme plays a major role not only in microRNA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1c092c40bfa703e2c37fa97302904b4
https://doi.org/10.1021/acs.biochem.2c00570
https://doi.org/10.1021/acs.biochem.2c00570
Autor:
Rachel M. Torrez, Shruti Nagaraja, Arya Menon, Louise Chang, Melanie D. Ohi, Amanda L. Garner
Publikováno v:
Biochemistry.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e15d4bd512ac7f7fbd4925231b2973ac
https://doi.org/10.1021/acs.biochem.2c00687
https://doi.org/10.1021/acs.biochem.2c00687
Autor:
Cory T. Reidl, Tahirah K. Heath, Iman Darwish, Rachel M. Torrez, Maxwell Moore, Elliot Gild, Boguslaw P. Nocek, Anna Starus, Richard C. Holz, Daniel P. Becker
Publikováno v:
Antibiotics, Vol 9, Iss 9, p 595 (2020)
Inhibitors of the bacterial enzyme dapE-encoded N-succinyl-l,l-diaminopimelic acid desuccinylase (DapE; EC 3.5.1.18) hold promise as antibiotics with a new mechanism of action. Herein we describe the discovery of a new series of indoline sulfonamide
Externí odkaz:
https://doaj.org/article/a098c382d39a4dc9b420906e26c19a56
Autor:
Pamela J. Schultz, Andrew Robertson, Osama G. Mohamed, Bailey A. Bell, Lisa A Caratelli, Rachel M. Torrez, Ashootosh Tripathi, Jorge Sandoval, Jennifer J. Schmidt, Amanda L. Garner, Paul A. Price, Arya Menon, Yihao Zhuang, Erin E. Gallagher, Catherine L. Hay
Publikováno v:
ACS Med Chem Lett
[Image: see text] MicroRNAs (miRNAs) are a family of small noncoding RNAs that regulate gene expression. Due to their important activity in the fine-tuning of protein translation, abnormal expression of miRNAs has been linked to many human diseases,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ba2e1ba26e0ac0d976206235c221d7d
https://doi.org/10.1021/acsmedchemlett.1c00046
https://doi.org/10.1021/acsmedchemlett.1c00046
Autor:
Anna Starus, Maxwell Moore, Elliot Gild, Tahirah K. Heath, Iman Darwish, Rachel M Torrez, Cory T. Reidl, Daniel P. Becker, Richard C. Holz, Boguslaw Nocek
Publikováno v:
Antibiotics, Vol 9, Iss 595, p 595 (2020)
Antibiotics
Volume 9
Issue 9
Antibiotics
Volume 9
Issue 9
Inhibitors of the bacterial enzyme dapE-encoded N-succinyl-l,l-diaminopimelic acid desuccinylase (DapE
EC 3.5.1.18) hold promise as antibiotics with a new mechanism of action. Herein we describe the discovery of a new series of indoline sulfonam
EC 3.5.1.18) hold promise as antibiotics with a new mechanism of action. Herein we describe the discovery of a new series of indoline sulfonam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2885b0944f373c72b942eedaec7d5c31
https://www.mdpi.com/2079-6382/9/9/595
https://www.mdpi.com/2079-6382/9/9/595
Publikováno v:
eLife
eLife, Vol 7 (2018)
Strutt, SC; Torrez, RM; Kaya, E; Negrete, OA; & Doudna, JA. (2018). RNA-dependent RNA targeting by CRISPR-Cas9. eLife, 7. doi: 10.7554/eLife.32724. Lawrence Berkeley National Laboratory: Lawrence Berkeley National Laboratory. Retrieved from: http://www.escholarship.org/uc/item/1hz8w9tx
eLife, Vol 7 (2018)
Strutt, SC; Torrez, RM; Kaya, E; Negrete, OA; & Doudna, JA. (2018). RNA-dependent RNA targeting by CRISPR-Cas9. eLife, 7. doi: 10.7554/eLife.32724. Lawrence Berkeley National Laboratory: Lawrence Berkeley National Laboratory. Retrieved from: http://www.escholarship.org/uc/item/1hz8w9tx
Double-stranded DNA (dsDNA) binding and cleavage by Cas9 is a hallmark of type II CRISPR-Cas bacterial adaptive immunity. All known Cas9 enzymes are thought to recognize DNA exclusively as a natural substrate, providing protection against DNA phage a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3997acfc9435ed7408701fa857823724
https://escholarship.org/uc/item/1hz8w9tx
https://escholarship.org/uc/item/1hz8w9tx
