Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Rachel M Grattan"'
Autor:
Carolina Franco Nitta, Ellen W Green, Elton D Jhamba, Justine M Keth, Iraís Ortiz-Caraveo, Rachel M Grattan, David J Schodt, Aubrey C Gibson, Ashwani Rajput, Keith A Lidke, Bridget S Wilson, Mara P Steinkamp, Diane S Lidke
Publikováno v:
eLife, Vol 10 (2021)
Crosstalk between different receptor tyrosine kinases (RTKs) is thought to drive oncogenic signaling and allow therapeutic escape. EGFR and RON are two such RTKs from different subfamilies, which engage in crosstalk through unknown mechanisms. We com
Externí odkaz:
https://doaj.org/article/e31009dbd018455c9651fc5154625b67
Autor:
Hassan Dibaji, Ali Kazemi Nasaban Shotorban, Rachel M. Grattan, Shayna Lucero, David J. Schodt, Keith A. Lidke, Jonathan Petruccelli, Diane S. Lidke, Sheng Liu, Tonmoy Chakraborty
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-11 (2024)
Abstract Rapid, high-resolution volumetric imaging without moving heavy objectives or disturbing delicate samples remains challenging. Pupil-matched remote focusing offers a promising solution for high NA systems, but the fluorescence signal’s inco
Externí odkaz:
https://doaj.org/article/2c8b68af753b4a0d8309329f570171ff
Autor:
Simone C. Oostindie, Derek A. Rinaldi, Gijs G. Zom, Michael J. Wester, Desiree Paulet, Kusai Al-Tamimi, Els van der Meijden, Jennifer R. Scheick, Tessa Wilpshaar, Bart de Jong, Marloes Hoff-van den Broek, Rachel M. Grattan, Janita J. Oosterhoff, Julie Vignau, Sandra Verploegen, Peter Boross, Frank J. Beurskens, Diane S. Lidke, Janine Schuurman, Rob N. de Jong
Publikováno v:
Nature Biotechnology. 40:1509-1519
The use of therapeutic monoclonal antibodies is constrained because single antigen targets often do not provide sufficient selectivity to distinguish diseased from healthy tissues. We present HexElect®, an approach to enhance the functional selectiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::37adbdc10c2c7fdd110d991a2ca6fa2f
https://doi.org/10.1038/s41587-022-01384-1
https://doi.org/10.1038/s41587-022-01384-1
Autor:
Diane S. Lidke, Keith A. Lidke, Julian A. Rojo, David J. Schodt, Michael J. Wester, Rachel M. Grattan, Emanuel Salazar-Cavazos, Elizabeth M. Bailey
Publikováno v:
J Vis Exp
Phosphorylation is a necessary posttranslational modification that regulates protein function and directs cell signaling outcomes. Current methods to measure protein phosphorylation cannot preserve the heterogeneity in phosphorylation across individu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b92900651dda7c657ae070a1a454ebb
https://doi.org/10.3791/63665-v
https://doi.org/10.3791/63665-v
Autor:
Rachel M. Grattan, Bridget S. Wilson, David J. Schodt, Diane S. Lidke, Aubrey C. Gibson, Elton D. Jhamba, Keith A. Lidke, Justine M. Keth, Ashwani Rajput, Iraís Ortiz-Caraveo, Ellen W. Green, Mara P. Steinkamp, Carolina Franco Nitta
Publikováno v:
eLife, Vol 10 (2021)
eLife
eLife
SUMMARYCrosstalk between disparate membrane receptors is thought to drive oncogenic signaling and allow for therapeutic resistance. EGFR and RON are members of two unique receptor tyrosine kinase (RTK) subfamilies that engage in crosstalk through unk
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6686c507b9b0a0212638ffa661cbda23
https://elifesciences.org/articles/63678
https://elifesciences.org/articles/63678
Autor:
Carolina Franco Nitta, Ellen W Green, Elton D Jhamba, Justine M Keth, Iraís Ortiz-Caraveo, Rachel M Grattan, David J Schodt, Aubrey C Gibson, Ashwani Rajput, Keith A Lidke, Bridget S Wilson, Mara P Steinkamp, Diane S Lidke
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::04c6badbdd2282950f0686f595ecb97d
https://doi.org/10.7554/elife.63678.sa2
https://doi.org/10.7554/elife.63678.sa2
Autor:
Simone C, Oostindie, Derek A, Rinaldi, Gijs G, Zom, Michael J, Wester, Desiree, Paulet, Kusai, Al-Tamimi, Els, van der Meijden, Jennifer R, Scheick, Tessa, Wilpshaar, Bart, de Jong, Marloes, Hoff-van den Broek, Rachel M, Grattan, Janita J, Oosterhoff, Julie, Vignau, Sandra, Verploegen, Peter, Boross, Frank J, Beurskens, Diane S, Lidke, Janine, Schuurman, Rob N, de Jong
Publikováno v:
Nature biotechnology. 40(10)
The use of therapeutic monoclonal antibodies is constrained because single antigen targets often do not provide sufficient selectivity to distinguish diseased from healthy tissues. We present HexElect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2f9d47a2d156096e415c018ab095c482
https://pubmed.ncbi.nlm.nih.gov/35879363
https://pubmed.ncbi.nlm.nih.gov/35879363
Publikováno v:
J Leukoc Biol
Infiltration of acute lymphoblastic leukemia (ALL) blasts into the CNS remains as a major clinical problem, with high risk for chemotherapy-resistant relapse and treatment-related morbidity. Despite the common inclusion of CNS prophylaxis treatments
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88fc4c7e87ef74b9a71270db59ded8f9
https://pubmed.ncbi.nlm.nih.gov/30702754
https://pubmed.ncbi.nlm.nih.gov/30702754
Autor:
Bruna Jacobson, Christopher P. Mattison, Avanika Mahajan, Cédric Cleyrat, Lydia Tapia, Rachel M. Grattan, M. Frank Erasmus, William S. Hlavacek, Shayna R. Lucero, Mark Schuyler, Bridget S. Wilson, Lama A. Youssef
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 198(3)
Ag-mediated crosslinking of IgE–FcεRI complexes activates mast cells and basophils, initiating the allergic response. Of 34 donors recruited having self-reported shrimp allergy, only 35% had significant levels of shrimp-specific IgE in serum and m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ba34cfaa5042bf514bf3666154d885a
https://pubmed.ncbi.nlm.nih.gov/28039304
https://pubmed.ncbi.nlm.nih.gov/28039304
Autor:
Mara P. Steinkamp, Diane S. Lidke, Elton D. Jhamba, Carolina Franco Nitta, Rachel M. Grattan, Ellen W. Hatch, Bridget S. Wilson, Justine M. Keth
Publikováno v:
Biophysical Journal. 114:462a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7b0456eec4996fe5ed28dcd4f4077e12
https://doi.org/10.1016/j.bpj.2017.11.2552
https://doi.org/10.1016/j.bpj.2017.11.2552