Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Rachel Luu"'
Publikováno v:
Vaccines, Vol 4, Iss 2, p 14 (2016)
Endosomal Toll-like receptors (TLR) such as TLR3, 7, 8 and 9 recognize pathogen associated nucleic acids. While DNA sequence does influence degree of binding to and activation of TLR9, it also appears to influence the ability of the ligand to reach t
Externí odkaz:
https://doaj.org/article/1a4951b0392c4b94986a5382708cbae1
Autor:
Ian Macreadie, Yen Nhi (Rachel) Luu
Publikováno v:
Open Journal of Social Sciences. :24-31
Yeasts are eukaryotes like us, and they have informed us about our cellular and molecular biology for many decades. They are unicellular and live with 6000 genes, carrying out many of the same processes that we do. Like us, yeast exhibit the same pro
Autor:
Arthur M. Krieg, Marion Jurk, Rachel Luu, Alain Vicari, Bettina Schulte, Ghania Chikh, Denise Richardt-Pargmann, Andrea Kritzler, Catherine Lampron, Jörg Vollmer
Publikováno v:
Nucleic Acid Therapeutics. 21:201-214
Microbial infections trigger a multiplicity of responses in the host via innate immune sensors, including the Toll-like receptors (TLRs). TLR7 and TLR8, located in endosomes, detect pathogen-derived RNA, which can be mimicked by synthetic single-stra
Autor:
Rachel Luu, Alain Vicari, Ningli Zhang, Shawn R. Makinen, Risini D. Weeratna, Douglas C. Hanson, Shobhna Patel, Arthur M. Krieg
Publikováno v:
Cancer immunology, immunotherapy : CII. 58(4)
The anti-tumor properties of Toll-like receptor (TLR) 9 agonist CpG oligodeoxynucleotides (ODN) are enhanced by combinations with several cytotoxic chemotherapy regimens. The mechanisms of this added benefit, however, remain unclear. We now report th