Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Rachel Lullo"'
Autor:
Francesca Fata, Radosveta Gencheva, Qing Cheng, Rachel Lullo, Matteo Ardini, Ilaria Silvestri, Federica Gabriele, Rodolfo Ippoliti, Christina A. Bulman, Judy A. Sakanari, David L. Williams, Elias S.J. Arnér, Francesco Angelucci
Publikováno v:
Redox Biology, Vol 51, Iss , Pp 102278- (2022)
Enzymes in the thiol redox systems of microbial pathogens are promising targets for drug development. In this study we characterized the thioredoxin reductase (TrxR) selenoproteins from Brugia malayi and Onchocerca volvulus, filarial nematode parasit
Externí odkaz:
https://doaj.org/article/3ad78271ac504fecbdcd50d7a6474ac7
Autor:
Valentina Petukhova, Samuel Aboagye, Matteo Ardini, Rachel Lullo, Margaret Byrne, Lucy Martin, Francesca Fata, Federica Gabriele, Rodolfo Ippoliti, Wai Li Ling, Grégory Effantin, Luke Harding, Dejan Nikolic, Daniel Lantvit, Bikash Dangi, Vamshikrishna Gone, Jeremy Johnson, Gregory Thatcher, Francesco Angelucci, David Williams, Pavel Petukhov
Only one drug, praziquantel, is available for treating schistosomiasis, a disease affecting more than 200 million people. Laboratory studies have shown that schistosome worms can develop resistance to praziquantel and low cure rates from mass drug ad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97d86a36268bc208b4a3a9fdecfc0b73
https://hdl.handle.net/11697/194259
https://hdl.handle.net/11697/194259
Publikováno v:
Journal of Inorganic Biochemistry. 222:111493
Alzheimer's disease is a fatal neurological disorder affecting millions of people worldwide with an increasing patient population as average life expectancy increases. Accumulation of amyloid beta (Aβ) plaques is characteristic of the disease and ha