Zobrazeno 1 - 10
of 116
pro vyhledávání: '"Rachel Lu"'
Autor:
Emily A. Day, Logan K. Townsend, Sonia Rehal, Battsetseg Batchuluun, Dongdong Wang, Marisa R. Morrow, Rachel Lu, Lucie Lundenberg, Jessie H. Lu, Eric M. Desjardins, Tyler K.T. Smith, Amogelang R. Raphenya, Andrew G. McArthur, Morgan D. Fullerton, Gregory R. Steinberg
Publikováno v:
iScience, Vol 26, Iss 11, Pp 108269- (2023)
Summary: Atherosclerotic cardiovascular disease is characterized by both chronic low-grade inflammation and dyslipidemia. The AMP-activated protein kinase (AMPK) inhibits cholesterol synthesis and dampens inflammation but whether pharmacological acti
Externí odkaz:
https://doaj.org/article/3e71dfd38cb24b0fa08de9d413beeee1
Publikováno v:
The European Journal of Health Economics. 24:717-733
A randomized trial testing digital medicine support models for mild-to-moderate alcohol use disorder
Autor:
Andrew Quanbeck, Ming-Yuan Chih, Linda Park, Xiang Li, Qiang Xie, Alice Pulvermacher, Samantha Voelker, Rachel Lundwall, Katherine Eby, Bruce Barrett, Randall Brown
Publikováno v:
npj Digital Medicine, Vol 7, Iss 1, Pp 1-10 (2024)
Abstract This paper reports the results of a hybrid effectiveness-implementation randomized trial that systematically varied levels of human oversight required to support the implementation of a digital medicine intervention for persons with mild-to-
Externí odkaz:
https://doaj.org/article/b5597d76319542a1a0136e1e88173d4e
Autor:
Eric M. Desjardins, Brennan K. Smith, Emily A. Day, Serge Ducommun, Matthew J. Sanders, Joshua P. Nederveen, Rebecca J. Ford, Stephen L. Pinkosky, Logan K. Townsend, Robert M. Gutgesell, Rachel Lu, Kei Sakamoto, Gregory R. Steinberg
Publikováno v:
Desjardins, E M, Smith, B K, Day, E A, Ducommun, S, Sanders, M J, Nederveen, J P, Ford, R J, Pinkosky, S L, Townsend, L K, Gutgesell, R M, Lu, R, Sakamoto, K & Steinberg, G R 2022, ' The phosphorylation of AMPKβ1 is critical for increasing autophagy and maintaining mitochondrial homeostasis in response to fatty acids ', Proceedings of the National Academy of Sciences of the United States of America, vol. 119, no. 48, e2119824119 . https://doi.org/10.1073/pnas.2119824119
Fatty acids are vital for the survival of eukaryotes, but when present in excess can have deleterious consequences. The AMP-activated protein kinase (AMPK) is an important regulator of multiple branches of metabolism. Studies in purified enzyme prepa
Publikováno v:
In European Journal of Operational Research 1 May 2013 226(3):615-625
Autor:
Wilfredo Manuel R. Torralba, Marlyn Thomas Savio, Xieyining Huang, Priyanka Manchanda, Miriah Steiger, Timir Bharucha, María Martín López, Keanan J. Joyner, Rachel Lutz Guevara
Publikováno v:
Frontiers in Psychiatry, Vol 15 (2024)
Externí odkaz:
https://doaj.org/article/4cf56ed4e1134218a5c4691e92d0fa84
Autor:
Peter Laner, Christian Rossi, Rachel Luethi, Filippo Favilli, Irena Bertoncelj, Guido Plassmann, Rudolf M. Haller
Publikováno v:
Ecological Indicators, Vol 164, Iss , Pp 112145- (2024)
Over the past decade, ecological connectivity has entered the political agenda, especially within the European transnational context. This evolution has driven the development of structural ecological connectivity and landscape permeability methodolo
Externí odkaz:
https://doaj.org/article/101b5c61e74a4a2ab5346829b8e44c4a
Autor:
Brian Chen, Ying Isabel Chen, Joseph P. Newhouse, Jianchao Quan, Janet Tinkei Lam, Karen Eggleston, Jui-fen Rachel Lu, Toshiaki Iizuka, Talitha L Feenstra, Jeroen N. Struijs, Gabriel M. Leung, Chih-Hung Chen, Beatriz Rodríguez-Sánchez
Publikováno v:
European Journal of Health Economics, 21(5), 689-702. Springer Verlag
European Journal of Health Economics, 21(5), 689-702. SPRINGER
European Journal of Health Economics, 21(5), 689-702. SPRINGER
Improvements in medical treatment have contributed to rising health spending. Yet there is relatively little evidence on whether the spending increase is “worth it” in the sense of producing better health outcomes of commensurate value—a critic
Autor:
Gregory R. Steinberg, Natalia McInnes, Brennan K. Smith, Rachel Lu, Sibylle Hess, Emily A. Day, Pedrum Mohammadi-Shemirani, Andrew G. McArthur, Marisa R Morrow, Robert M Gutgesell, Amogelang R. Raphenya, Mostafa Kabiri, Guillaume Paré, Rebecca J. Ford, Hertzel C. Gerstein
Publikováno v:
Nature Metabolism. 1:1202-1208
Metformin is the most commonly prescribed medication for type 2 diabetes, owing to its glucose-lowering effects, which are mediated through the suppression of hepatic glucose production (reviewed in refs. 1-3). However, in addition to its effects on
Autor:
Sandra S. Liu, Hong-Huei Wang, Jui-fen Rachel Lu, Edmund R. Becker, Yu-Ping Wen, Ji-Tian Sheu
Publikováno v:
BMC Health Services Research, Vol 21, Iss 1, Pp 1-10 (2021)
BMC Health Services Research
BMC Health Services Research
Background The high costs of chronic conditions call for new treatment approaches that reduce costs while ensuring desirable health outcomes. There has been a growing transformation of care delivery models from conventional referral systems to integr