Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Rachel Lawrence"'
Autor:
Tarek Al-Hammouri, Ricardo Almeida-Magana, Rachel Lawrence, Tom Duffy, Laura White, Edwina Burke, Sakunthala Kudahetti, Justin Collins, Prabhakar Rajan, Daniel Berney, Rhian Gabe, Greg Shaw, Yong-Jie Lu
Publikováno v:
BMC Cancer, Vol 23, Iss 1, Pp 1-9 (2023)
Abstract Background Treatment decisions in prostate cancer (PCa) rely on disease stratification between localised and metastatic stages, but current imaging staging technologies are not sensitive to micro-metastatic disease. Circulating tumour cells
Externí odkaz:
https://doaj.org/article/1ac2452886404d4fb80b726498c9fb57
Autor:
Corentin Bouvier, Rachel Lawrence, Francesca Cavallo, Wendy Xolalpa, Allan Jordan, Roland Hjerpe, Manuel S. Rodriguez
Publikováno v:
Cells, Vol 13, Iss 7, p 578 (2024)
Proteolysis-targeting chimeras (PROTACs) describe compounds that bind to and induce degradation of a target by simultaneously binding to a ubiquitin ligase. More generally referred to as bifunctional degraders, PROTACs have led the way in the field o
Externí odkaz:
https://doaj.org/article/4bd15c3cb64b401fa3a65fab7f0f52dc
Publikováno v:
Mutagenesis. 38:93-99
Pancreatic cancer still has one of the worst prognoses of all solid malignancies, despite developments in cancer knowledge and care. Research into pancreatic cancer has not fully translated into clinical improvements and as a result, fewer than 1% of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dd5c54a05db549422fae05e6184eb234
https://doi.org/10.1093/mutage/gead006
https://doi.org/10.1093/mutage/gead006
Publikováno v:
Sustainability Accounting, Management and Policy Journal. 13:765-802
Purpose This paper aims to demonstrate methods that sustainability-conscious brands can use to include their primary producers in the measurement and reporting of the environment and sustainability performance of their supply chains. It explores thre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::16811399e1f7a6fe5b2b390fe9e9b6b6
https://doi.org/10.1108/sampj-06-2021-0191
https://doi.org/10.1108/sampj-06-2021-0191
Publikováno v:
Spirituality in Clinical Practice. 8:149-160
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a8c0542d5656760fc412b1e91b3aae91
https://doi.org/10.1037/scp0000228
https://doi.org/10.1037/scp0000228
Publikováno v:
Journal of Applied Ecology. 56:2723-2731
Grazing can have considerable ecological impacts when managed inappropriately, however livestock production is a significant contributor to global food security and the removal of land from production is not always a viable option. Grazing management
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::141eff1720e3df6bc632978a3f184bf3
https://doi.org/10.1111/1365-2664.13496
https://doi.org/10.1111/1365-2664.13496
Publikováno v:
Agriculture, Ecosystems & Environment. 281:134-144
Livestock grazing can lead to reduced ground cover and altered composition of pastures through the loss of palatable forage species and reduced litter cover. This negatively impacts landscape function and ultimately livestock production. Grazing live
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6e0c6bf4ed790117e2b18b50468de9f4
https://doi.org/10.1016/j.agee.2019.04.031
https://doi.org/10.1016/j.agee.2019.04.031
Autor:
Avipsa Ghosh, Sudhir M. Hande, Amber Balazs, Derek Barratt, Sabina Cosulich, Barry Davies, Sébastien Degorce, Kevin Embrey, Sonja Gill, Anders Gunnarsson, Giuditta Illuzzi, Peter Johnström, Jordan Lane, Carrie Larner, Rachel Lawrence, Elisabetta Leo, Andrew Madin, Elizabeth Martin, Lisa McWilliams, Lenka O’Connor, Mark O’Connor, Jonathan Orme, Fiona Pachl, Martin Packer, Andy Pike, Philip Rawlins, Marianne Schimpl, Magnus Schou, Anna Staniszewska, Wenzhan Yang, James Yates, Andrew Zhang, XiaoLa Zheng, Stephen Fawell, Petra Hamerlik, Jeffrey Johannes
Publikováno v:
Cancer Research. 82:6302-6302
PARP inhibitors exploit defects in DNA repair pathways to selectively target cancerous cells via PARP1 catalytic inhibition and PARP1 trapping onto the DNA. All known clinical PARP1 inhibitors bind at the same site at the catalytic center of the enzy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::288251eb61b3a0254c30186cb54c9b42
https://doi.org/10.1158/1538-7445.am2022-6302
https://doi.org/10.1158/1538-7445.am2022-6302
Publikováno v:
Journal of Geometry. 108:1013-1029
An $n$-arc in a projective plane is a collection of $n$ distinct points in the plane, no three of which lie on a line. Formulas counting the number of $n$-arcs in any finite projective plane of order $q$ are known for $n \le 8$. In 1995, Iampolskaia,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2871933abd85724374e1f5f55071dbea
https://doi.org/10.1007/s00022-017-0391-1
https://doi.org/10.1007/s00022-017-0391-1
Abstract 1757: Developing sensitive assays to facilitate hit identification of RNA modifying enzymes
Autor:
Grace Boden, Bethany Smith, Rachel Lawrence, Stuart A. Best, Thomas Alanine, Stuart Thomson, Chris Tomlinson, Scott Pollack, Ross Wilkie, Allan M. Jordan, James Wasp, John Unitt
Publikováno v:
Cancer Research. 80:1757-1757
N-6-methyladenosine (m6A) is the most abundant RNA chemical modification found in the eukaryotic transcriptome. It is a dynamic and reversible modification which plays a role in RNA function across a wide range of biological processes. Dysregulation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a0359a38bccd49ee296040d43d04b4b3
https://doi.org/10.1158/1538-7445.am2020-1757
https://doi.org/10.1158/1538-7445.am2020-1757