Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Rachel Labell"'
Autor:
Aaron F.H. Lum, Jennifer L. McCallan, Terry O. Matsunaga, Michaelann Tartis, Rachel Labell, Susanne M. Stieger, Katherine W. Ferrara
Publikováno v:
Ultrasound in Medicine & Biology. 32:1771-1780
Drug delivery vehicles that combine ultrasonic and molecular targeting are shown to locally concentrate a drug in a region-of-interest. The drug delivery vehicles, referred to as acoustically active lipospheres (AALs), are microbubbles surrounded by
Autor:
Thomas R. Porter, Rachel Labell, Reena Zutshi, William C. Culp, Evan C. Unger, Terry O. Matsunaga
Publikováno v:
Advanced Drug Delivery Reviews. 56:1291-1314
Lipid-coated microbubbles represent a new class of agents with both diagnostic and therapeutic applications. Microbubbles have low density. Stabilization of microbubbles by lipid coatings creates low-density particles with unusual properties for diag
Autor:
Marek Romanowski, Rachel Labell, Rajan Ramaswami, Evan C. Unger, Joshua D. Williams, Rachael Lansdown, Robert H. Sweitzer
Publikováno v:
Journal of Controlled Release. 91:167-172
Camptothecin-based drugs, because of their poor solubility and labile lactone ring, pose challenges for drug delivery. The purpose of this research was to develop a nanoparticle delivery system for camptotheca alkaloids. After initial investigations
Autor:
M.J. Shortencarier, Patricia A. Schumann, Katherine W. Ferrara, Rachel Labell, Terry O. Matsunaga, Paul K. Dayton
Publikováno v:
IEEE Ultrasonics Symposium, 2005..
Autor:
Reena Zutshi, A. Kerschen, Rachel Labell, Terry O. Matsunaga, K. Penrose, E. Unger, Patricia A. Schumann
Publikováno v:
AIP Conference Proceedings.
Angiogenic vessels at tumor sites are leaky and allow particles less than 400 nm to pass through. We have developed targeted nanodroplets that are less than 400 nm in size and are capable of encapsulating drug molecules which can be released at the t
Autor:
John Lof, Paul K. Dayton, Rachel Labell, Terry O. Matsunaga, Katherine W. Ferrara, Susannah H. Bloch, Thomas R. Porter, Feng Xie, Reena Zutshi, Evan C. Unger
Publikováno v:
AIP Conference Proceedings.
Compared to other modalities that might be employed for molecular imaging, ultrasound has some unique features. It is portable; highly adapted to the surgical environment; can be used for cavitation, heating, and tissue ablation; and is exquisitely s
Publikováno v:
Angewandte Chemie (International ed. in English). 40(16)
A critical spacer arm length necessary to promote efficient binding of the HIV-1 surface glycoprotein rgp120 to several synthetic galactosyl-conjugated lipids, reconstituted into planar lipid bilayers, was identified. This should aid the design of an
Publikováno v:
Angewandte Chemie (International ed. in English). 40(12)
Autor:
Katherine W. Ferrara, Patricia A. Schumann, Susannah H. Bloch, Rachel Labell, Terry O. Matsunaga, Michaelann Shortencarier, Paul K. Dayton
Publikováno v:
The Journal of the Acoustical Society of America. 117:2473-2473
The goal is to create a strategy for localized drug delivery using engineered delivery vehicles and ultrasound energy. These drug delivery vehicles, referred to as acoustically active lipospheres (AALs), consist of small gas bubbles surrounded by thi
Autor:
Unger, Evan, Matsunaga, Terry O., Zutshi, Reena, Labell, Rachel, Porter, Thomas R., Lof, John, Feng Xie, Ferrara, Katherine, Dayton, Paul, Bloch, Susannah
Publikováno v:
AIP Conference Proceedings; 2005, Vol. 754 Issue 1, p58-61, 4p