Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Rachel L. Ruhlen"'
Autor:
Eric J. Snider, Lex C. Towns, Rachel L. Ruhlen, Vineet K. Singh, Brian F. Degenhardt, Vanessa Pazdernik, Neil J. Sargentini
Publikováno v:
Journal of Osteopathic Medicine. 114:768-776
Context: Mobilization of a joint affects local tissue directly but may also have other effects that are mediated through the central nervous system. Objective: To identify differential gene expression in the spinal cords of rats with or without infla
Autor:
Bart D. Worthington, Jane C. Johnson, Eric J. Snider, Vineet K. Singh, Neil J. Sargentini, Brian F. Degenhardt, Rachel L. Ruhlen, Vanessa Pazdernik
Publikováno v:
Journal of Osteopathic Medicine. 113:738-752
Context: Animal models can be used to investigate manual therapy mechanisms, but testing manipulation in animal models is problematic because animals cannot directly report their pain. Objective: To develop a rat model of inflammatory joint injury to
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 127:83-95
Development and differentiation of the prostate from the fetal urogenital sinus (UGS) is dependent on androgen action via androgen receptors (AR) in the UGS mesenchyme. Estrogens are not required for prostate differentiation but do act to modulate an
Autor:
Rachel L. Ruhlen, F S vom Saal, Wade V. Welshons, Julia A. Taylor, James Kirkpatrick, Jiude Mao
Publikováno v:
Journal of Developmental Origins of Health and Disease. 2:36-48
Exposure of fetuses to endocrine disrupting chemicals (EDCs), such as the estrogenic drug diethylstilbestrol (DES), disrupts development of the reproductive system and affects other aspects of adult phenotype including diseases, consistent with the d
Autor:
Huidong Shi, George E. Rottinghaus, Edward R. Sauter, Ruth S. MacDonald, Weizhu Zhu, Wenyi Qin, John E. Hewett, Rachel L. Ruhlen, Yin Chieh Chen
Publikováno v:
Nutrition and Cancer. 61:238-244
We determined if soy isoflavones have dose-related estrogenic and methylation effects. Thirty-four healthy premenopausal women were randomized to 40 mg or 140 mg isoflavones daily through one menstrual cycle. Breast specific and systemic estrogenic e
Autor:
Beth Kliethermes, Roger de la Torre, Rachel L. Ruhlen, John E. Hewett, Stephen Scott, Edward R. Sauter, Krishnamohan Basarakodu
Publikováno v:
Cancer Detection and Prevention. 32:149-155
Background : Obesity is linked to the development of postmenopausal breast cancer, and some studies indicate obesity predicts a worse prognosis for premenopausal women who develop the disease. It was our hypothesis that proteins associated with breas
Autor:
Hormoz Ehya, George E. Rottinghaus, William R. Lamberson, John K. Tracy, Rachel L. Ruhlen, Edward R. Sauter, Weizhu Zhu, Jenny Haubner
Publikováno v:
Nutrition and Cancer. 59:269-277
Women's Health Initiative findings indicate that hormone replacement therapy may increase breast cancer and cardiovascular disease risk. Black cohosh extract (BCE) is a popular alternative that reduced menopausal symptoms in several clinical trials.
Autor:
Edward R. Sauter, Rachel L. Ruhlen
Publikováno v:
PROTEOMICS – CLINICAL APPLICATIONS. 1:845-852
Proteomic analysis of breast fluids has wide-ranging clinical applications. Protein expression in nipple aspirate fluid and breast cyst fluid may prove valuable for the detection and monitoring of breast cancer, but has been hampered by the lack of a
Autor:
Frederick S. vom Saal, Wade V. Welshons, Catherine A. Richter, Rachel L. Ruhlen, Julia A. Taylor
Publikováno v:
Environmental Health Perspectives
Background Hormonal alterations during development have lifelong effects on the prostate gland. Endogenous estrogens, including 17β-estradiol (E2), and synthetic estrogenic endocrine disruptors, such as bisphenol A (BPA), have similar effects on pro
Autor:
Carl E. Orazio, Wade V. Welshons, Frederick S. vom Saal, Barbara M. Judy, Kembra L. Howdeshell, Rachel L. Ruhlen, Julia A. Taylor, Paul H. Peterman
Publikováno v:
Environmental Health Perspectives
Bisphenol A (BPA) is a monomer with estrogenic activity that is used in the production of food packaging, dental sealants, polycarbonate plastic, and many other products. The monomer has previously been reported to hydrolyze and leach from these prod