Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Rachel L. Morgan"'
Autor:
Takayuki Sugiyama, Donna P. Frazier, Pankaj Taneja, Robert D. Kendig, Rachel L. Morgan, Lauren A. Matise, Sarah J. Lagedrost, Kazushi Inoue
Publikováno v:
Clinical Medicine Insights: Oncology, Vol 2 (2008)
Summary Dmp1 (cyclin D-interacting myb-like protein 1; also called Dmtf1) is a transcription factor that has been isolated in a yeast two-hybrid screen through its binding property to cyclin D2. Dmp1 directly binds to and activates the Arf promoter a
Externí odkaz:
https://doaj.org/article/6a2c82e498194e2aae4623d27d65aee8
Autor:
Kazushi Inoue, Guangchao Sui, Sarah J. Lagedrost, Elizabeth A. Fry, Rachel L. Morgan, Takayuki Sugiyama, Dejan Maglic, Fumitake Kai, Robert D. Kendig, Donna P. Frazier
PDF file - 786K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b4cebbb2484bbfe6012b87aed732b80
https://doi.org/10.1158/0008-5472.22394465
https://doi.org/10.1158/0008-5472.22394465
Autor:
Kazushi Inoue, Guangchao Sui, Sarah J. Lagedrost, Elizabeth A. Fry, Rachel L. Morgan, Takayuki Sugiyama, Dejan Maglic, Fumitake Kai, Robert D. Kendig, Donna P. Frazier
PDF file - 49K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46a4a6d5a0b7ef7a80ddcf4f029c99bb
https://doi.org/10.1158/0008-5472.22394462
https://doi.org/10.1158/0008-5472.22394462
Autor:
Kazushi Inoue, Guangchao Sui, Sarah J. Lagedrost, Elizabeth A. Fry, Rachel L. Morgan, Takayuki Sugiyama, Dejan Maglic, Fumitake Kai, Robert D. Kendig, Donna P. Frazier
The transcription factor Dmp1 is a Ras/HER2-activated haplo-insufficient tumor suppressor that activates the Arf/p53 pathway of cell-cycle arrest. Recent evidence suggests that Dmp1 may activate p53 independently of Arf in certain cell types. Here, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::74811d246a423a731bebe2eacb4c0214
https://doi.org/10.1158/0008-5472.c.6504035.v1
https://doi.org/10.1158/0008-5472.c.6504035.v1
Autor:
Rachel L Morgan, Nilofar Behbahani-Nejad, Judith Endres, M Asif Amin, Nick J Lepore, Yuxuan Du, Andrew Urquhart, Kevin C Chung, David A Fox
Publikováno v:
PLoS ONE, Vol 11, Iss 9, p e0162008 (2016)
Aminopeptidase N/CD13 is highly expressed by fibroblast like synoviocytes (FLS) and may play a role in rheumatoid arthritis (RA). CD13 was previously detected in human synovial fluid where it was significantly increased in RA compared to osteoarthrit
Externí odkaz:
https://doaj.org/article/37eb550c9b1c479280afc2873c1fa45a
Autor:
Takayuki Sugiyama, Rachel L. Morgan, Elizabeth A. Fry, Kazushi Inoue, Guangchao Sui, Dejan Maglic, Fumitake Kai, Donna P. Frazier, Sarah J. Lagedrost, Robert D. Kendig
Publikováno v:
Cancer Research. 72:1740-1750
The transcription factor Dmp1 is a Ras/HER2-activated haplo-insufficient tumor suppressor that activates the Arf/p53 pathway of cell-cycle arrest. Recent evidence suggests that Dmp1 may activate p53 independently of Arf in certain cell types. Here, w
Publikováno v:
Cancer Research. 68:4487-4490
The Ras-activated transcription factor DMP1 can stimulate Arf transcription to promote p53-dependent cell arrest. One recent study deepens the pathophysiologic significance of this pathway in cancer, first, by identifying DMP1 losses in human lung ca
Evidence for citrullinated inhibitor of DNA binding 1 as a novel autoantigen in rheumatoid arthritis
Autor:
Ray A Ohara, Gautam Edhayan, Henriette A Remmer, Rachel L Morgan, M Asif Amin, W Alexander Stinson, Jerry Graham, Josh S Kim, Phillip L Campbell, Ali S Arbab, David A Fox, Jeffrey H Ruth
Publikováno v:
The Journal of Immunology. 196:188.12-188.12
Inhibitor of DNA binding 1 (Id1) is a nuclear transcription factor that is primarily fibroblast derived with elevated expression in rheumatoid arthritis (RA) synovial tissues (STs) and synovial fluids (SFs). Id1 is potently angiogenic in RA, and targ
Autor:
Lauren A. Matise, Sarah J. Lagedrost, Rachel L. Morgan, Pankaj Taneja, Takayuki Sugiyama, Kazushi Inoue, Robert D. Kendig, Donna P. Frazier
Publikováno v:
Clinical Medicine. Oncology
Clinical Medicine Insights: Oncology, Vol 2 (2008)
Clinical Medicine Insights: Oncology, Vol 2 (2008)
SummaryDmp1 (cyclin D-interacting myb-like protein 1; also called Dmtf1) is a transcription factor that has been isolated in a yeast two-hybrid screen through its binding property to cyclin D2. Dmp1 directly binds to and activates the Arf promoter an
Autor:
Takayuki Sugiyama, Kazushi Inoue, Donna P. Frazier, Pankaj Taneja, Mark C. Willingham, Rachel L. Morgan
Publikováno v:
Expert review of molecular diagnostics. 8(4)
Lung cancer is the most lethal carcinoma worldwide. Mutations of p53, inactivation of p16(INK4a), and overexpression of cyclins E, A and B are independently associated with poor prognoses of patients, while the prognostic value of cyclin D1 or RB exp