Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Rachel L. Manthe"'
Autor:
Rachel L. Manthe, Silvia Muro
Publikováno v:
Bioengineering & Translational Medicine. 2:109-119
Targeting of drug nanocarriers (NCs) to intercellular adhesion molecule-1 (ICAM-1), an endothelial-surface protein overexpressed in many pathologies, has shown promise for therapeutic delivery into and across this lining. Yet, due to the role of ICAM
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7f229979a3ae9568ca712cf22dcef8fb
https://doi.org/10.1002/btm2.10050
https://doi.org/10.1002/btm2.10050
Autor:
Wei Zheng, Silvia Muro, Rachel L. Manthe, Michael Hildreth, Jeffrey A. Rappaport, Melani Solomon, Vinay Veluvolu, Dencho Gugutkov, Juan J. Marugan, Yan Long
Induction of lysosomal exocytosis alleviates lysosomal storage of undigested metabolites in cell models of lysosomal disorders (LDs). However, whether this strategy affects other vesicular compartments, e.g., those involved in endocytosis, is unknown
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5552c2746c9eb2e1d0c283be0b910f6
https://europepmc.org/articles/PMC6806345/
https://europepmc.org/articles/PMC6806345/
Publikováno v:
Biomacromolecules. 17:3127-3137
Targeting of drug carriers to endocytic cell receptors facilitates intracellular drug delivery. Carrier size and number of targeting moieties (valency) influence cell binding and uptake. However, how these parameters influence receptor-mediated cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4d911c7d199ab375068741b0fa378d5
https://doi.org/10.1021/acs.biomac.6b00493
https://doi.org/10.1021/acs.biomac.6b00493
A Comparative Study on the Alterations of Endocytic Pathways in Multiple Lysosomal Storage Disorders
Publikováno v:
Molecular Pharmaceutics. 13:357-368
Many cellular activities and pharmaceutical interventions involve endocytosis and delivery to lysosomes for processing. Hence, lysosomal processing defects can cause cell and tissue damage, as in lysosomal storage diseases (LSDs) characterized by lys
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4bceda4a8ad325232ae21a627000084
https://doi.org/10.1021/acs.molpharmaceut.5b00542
https://doi.org/10.1021/acs.molpharmaceut.5b00542
Publikováno v:
Molecular Pharmaceutics. 12:1366-1376
Pharmaceutical intervention often requires therapeutics and/or their carriers to enter cells via endocytosis. Therefore, endocytic aberrancies resulting from disease represent a key, yet often overlooked, parameter in designing therapeutic strategies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8eb4747aba8abda276289cae55c84d09
https://doi.org/10.1021/mp5005959
https://doi.org/10.1021/mp5005959
Autor:
Rachel L, Manthe, Silvia, Muro
Publikováno v:
Bioengineering & Translational Medicine
Targeting of drug nanocarriers (NCs) to intercellular adhesion molecule‐1 (ICAM‐1), an endothelial‐surface protein overexpressed in many pathologies, has shown promise for therapeutic delivery into and across this lining. However, due to the ro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d9328544d607cceac1b60c72c2cdb789
https://pubmed.ncbi.nlm.nih.gov/28713860
https://pubmed.ncbi.nlm.nih.gov/28713860
Publikováno v:
Molecular Pharmaceutics. 7:1880-1898
Next to surgical resection, tumor ablation is a commonly used intervention in the treatment of solid tumors. Tumor ablation methods include thermal therapies, photodynamic therapy, and reactive oxygen species (ROS) producing agents. Thermal therapies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc66d0076bac22c5120277f09e3a5ea0
https://doi.org/10.1021/mp1001944
https://doi.org/10.1021/mp1001944
Publikováno v:
Polymer. 50:2281-2289
Biodegradable segmented l -tyrosine polyurethanes (LTUs) have been developed using a tyrosine based chain extender desaminotyrosine-tyrosyl-hexyl ester (DTH). Two such biodegradable LTUs, polycaprolactone diol-hexamethylene diisocyanate-desaminotyros
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::91c35072a52bc4590f46c52621bc30e0
https://doi.org/10.1016/j.polymer.2009.02.048
https://doi.org/10.1016/j.polymer.2009.02.048
Autor:
Rachel L. Manthe, Silvia Muro
Publikováno v:
Handbook of Nanobiomedical Research: Fundamentals, Applications and Recent Developments(In 4 Volumes)Volume 1: Materials for NanomedicineVolume 2: Applications in TherapyVolume 3: Applications in DiagnosticsVolume 4: Biology, Safety and Novel Concepts in Nanomedicine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4df761faf3ed1eb20f29045c1974d148
https://doi.org/10.1142/9789814520652_0025
https://doi.org/10.1142/9789814520652_0025
Autor:
W Russ, Algar, Juan B, Blanco-Canosa, Rachel L, Manthe, Kimihiro, Susumu, Michael H, Stewart, Philip E, Dawson, Igor L, Medintz
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1025
Quantum dots (QDs) are well-established as photoluminescent nanoparticle probes for in vitro or in vivo imaging, sensing, and even drug delivery. A critical component of this research is the need to reliably conjugate peptides, proteins, oligonucleot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ab8c0285fdccf5137ec71c23b146dfb6
https://pubmed.ncbi.nlm.nih.gov/23918329
https://pubmed.ncbi.nlm.nih.gov/23918329