Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Rachel L. Gessner"'
Autor:
James S. Chavez, Jennifer L. Rabe, Katia E. Niño, Harrison H. Wells, Rachel L. Gessner, Taylor S. Mills, Giovanny Hernandez, Eric M. Pietras
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Chronic inflammation is a common feature of aging and numerous diseases such as diabetes, obesity, and autoimmune syndromes and has been linked to the development of hematological malignancy. Blood-forming hematopoietic stem cells (HSC) can contribut
Externí odkaz:
https://doaj.org/article/95336b6d9bfa4ee79efcfe80a9a8020f
Autor:
Jason R. Myers, Eric M. Pietras, Rachel L Gessner, Katia E. Niño, James DeGregori, Nouraiz Ahmed, Pavel Davizon-Castillo, James S. Chavez, Hyunmin Kim, Taylor S. Mills, Zhonghe Ke, Robert S. Welner, Brett M. Stevens, Timm Schroeder, Beau M Idler, Dirk Loeffler, Giovanny Hernandez, Kelly C. Higa, John M. Ashton, Craig T. Jordan, Hideaki Nakajima, Jennifer L. Rabe
Publikováno v:
Journal of Experimental Medicine, 218 (6)
The Journal of Experimental Medicine
The Journal of Experimental Medicine
Hematopoietic stem cells (HSCs) are capable of entering the cell cycle to replenish the blood system in response to inflammatory cues; however, excessive proliferation in response to chronic inflammation can lead to either HSC attrition or expansion.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6c5f0deeced3592614adf5e265ef87c
https://hdl.handle.net/20.500.11850/480362
https://hdl.handle.net/20.500.11850/480362
Autor:
Zhonghe Ke, James DeGregori, Jason R. Myers, Robert S. Welner, Eric M. Pietras, Rachel L Gessner, Kelly C. Higa, Dirk Loeffler, Craig T. Jordan, Hideaki Nakajima, Beau M Idler, Taylor S. Mills, Jennifer L. Rabe, Giovanny Hernandez, Nouraiz Ahmed, John M. Ashton, Brett M. Stevens, James S. Chavez, Timm Schroeder, Hyunmin Kim
SummaryLoss of hematopoietic stem cell (HSC) quiescence and resulting clonal expansion are common initiating events in the development of hematological malignancy. Likewise, chronic inflammation related to aging, disease and/or tissue damage is assoc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a319b8016a4176f7c87f58e408e69246
https://doi.org/10.1101/2020.05.18.102830
https://doi.org/10.1101/2020.05.18.102830
Autor:
Taylor S. Mills, Courtney J. Fleenor, Nouraiz Ahmed, Brett M. Stevens, Jennifer L. Rabe, James S. Chavez, Eric M. Pietras, Rachel L Gessner, Dirk Loeffler, Beau M Idler, Timm Schroeder, Kelly C. Higa, Craig T. Jordan, Hideaki Nakajima, James Hagman, Hyunmin Kim, Zhonghe Ke, James DeGregori
Publikováno v:
Experimental Hematology. 88:S57
Hematopoietic stem cell (HSC) quiescence supports lifelong blood regeneration and guards against pre-leukemic clonal expansion. Acute exposure to the pro-inflammatory cytokine interleukin (IL)-1 drives myeloid cell production and HSC cell cycle entry
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::63045b16acbdc76ee7aead9868b8a5e1
https://doi.org/10.1016/j.exphem.2020.09.078
https://doi.org/10.1016/j.exphem.2020.09.078