Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Rachel L Poole"'
Autor:
Jonathan S Miller, Jeffrey L Barr, Lauren J Harper, Rachel L Poole, Thomas J Gould, Ellen M Unterwald
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e88026 (2014)
The Akt - GSK3 signaling pathway has been recently implicated in psychostimulant-induced behavioral and cellular effects. Here, the ability of cocaine to regulate the activity of Akt and GSK3 was investigated by measuring the phosphorylation states o
Externí odkaz:
https://doaj.org/article/d4b567fb87404a50bc2ad13d8c19f62b
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e39939 (2012)
Nicotine is known to enhance long-term hippocampus dependent learning and memory in both rodents and humans via its activity at nicotinic acetylcholinergic receptors (nAChRs). However, the molecular basis for the nicotinic modulation of learning is i
Externí odkaz:
https://doaj.org/article/f29af9eb0954437baca1ef6ffadb9abd
Publikováno v:
Chemical Senses. 41:45-52
Rodents are strongly attracted to the taste(s) of maltodextrins. A first step toward discovery of the underlying genes involves identifying phenotypic differences among inbred strains of mice. To do this, we used 5-s brief-access tests and 48-h 2-bot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af0f3aacb2065b2b22110fdb6022bcc7
https://doi.org/10.1093/chemse/bjv056
https://doi.org/10.1093/chemse/bjv056
Autor:
Makoto Ohmoto, Rachel L. Poole, Valery I. Shestopalov, Hillary T. Ellis, Tiffany R. Aleman, Claire H. Mitchell, Michael G. Tordoff, J. Kevin Foskett, Ichiro Matsumoto
Publikováno v:
Chemical Senses. 40:453-459
Taste compounds detected by G protein-coupled receptors on the apical surface of Type 2 taste cells initiate an intracellular molecular cascade culminating in the release of ATP. It has been suggested that this ATP release is accomplished by pannexin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e751bcd0a7ce6c54586e517c541e312
https://doi.org/10.1093/chemse/bjv025
https://doi.org/10.1093/chemse/bjv025
Publikováno v:
Psychopharmacology. 232:1207-1217
Deficits in executive functions underlie compulsive drug use, and understanding how nicotine influences these cognitive processes may provide important information on neurobiological substrates of nicotine addiction. Accumulating evidence suggests th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3352fc20c65877b1643f2c22857da66a
https://doi.org/10.1007/s00213-014-3754-4
https://doi.org/10.1007/s00213-014-3754-4
Publikováno v:
Learning & Memory. 21:457-467
Histone acetylation is essential for hippocampal memory formation in young adult rodents. Although dysfunctional histone acetylation has been associated with age-related memory decline in male rodents, little is known about whether histone acetylatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b75e16085076e1412c59baa30aaa74d
https://doi.org/10.1101/lm.034033.113
https://doi.org/10.1101/lm.034033.113
Autor:
Ellen M. Unterwald, Lauren J. Harper, Thomas J. Gould, Jonathan S. Miller, Xiangdang Shi, Rachel L. Poole
Publikováno v:
Psychopharmacology
Rational Memories return to a labile state following their retrieval and must undergo a process of reconsolidation to be maintained. Thus, disruption of cocaine reward memories by interference with reconsolidation may be therapeutically beneficial in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd94d7f37a1b7a2c093894760a0cd7b2
https://doi.org/10.1007/s00213-014-3491-8
https://doi.org/10.1007/s00213-014-3491-8
Publikováno v:
Behavioral Neuroscience. 128:588-593
Withdrawal from chronic nicotine is associated with cognitive deficits. Therapies that ameliorate cognitive deficits during withdrawal aid in preventing relapse during quit attempts. Withdrawal-induced deficits in contextual learning are associated w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09c948eafc07f45e0df333b987787144
https://doi.org/10.1037/bne0000003
https://doi.org/10.1037/bne0000003
Publikováno v:
Physiologybehavior. 170
Does eating good-tasting food influence body weight? To investigate, we first established some concentrations of sucralose and mineral oil in chow that mice strongly preferred. Then, in Experiment 1, we compared groups of 16 mice fed plain chow (i.e.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc15e9bafcb0ea8b1a8c9c0ba8d92b68
https://pubmed.ncbi.nlm.nih.gov/27988248
https://pubmed.ncbi.nlm.nih.gov/27988248
Publikováno v:
Neurobiology of learning and memory. 128
Nicotine is a major psychoactive and addictive component of tobacco. Although cessation of tobacco use produces various somatic and affective symptoms, withdrawal-related cognitive deficits are considered to be a critical symptom that predict relapse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1be2a9ff3625897641fe2719e78bc12
https://pubmed.ncbi.nlm.nih.gov/26775017
https://pubmed.ncbi.nlm.nih.gov/26775017