Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Rachel L O'Donnell"'
Autor:
Richard J. Edmondson, Nicola J. Curtin, Angelika Kaufmann, James Murray, Rachel L. O'Donnell, Richard O'Sullivan, Michelle Dixon, Peter Donoghue, Aiste McCormick
Purpose: DNA damage defects are common in ovarian cancer and can be used to stratify treatment. Although most work has focused on homologous recombination (HR), DNA double-strand breaks are repaired primarily by nonhomologous end joining (NHEJ). Defe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::974bc699b1afb3b966f191d88c7a40d1
https://doi.org/10.1158/1078-0432.c.6526470
https://doi.org/10.1158/1078-0432.c.6526470
Autor:
Richard J. Edmondson, Nicola J. Curtin, Angelika Kaufmann, James Murray, Rachel L. O'Donnell, Richard O'Sullivan, Michelle Dixon, Peter Donoghue, Aiste McCormick
Supplementary Table ST1. Patient characteristics for primary culture samples divided by NHEJ status. Supplementary figure S1. Predictors of NHEJ function A. pDNA-PKcs foci 1 hour after 2 Gy IR normalised to untreated controls. Foci were counted acros
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53943ed17c7d6608f31848d1ec1a1eb4
https://doi.org/10.1158/1078-0432.22466892
https://doi.org/10.1158/1078-0432.22466892
Publikováno v:
Ultrasound. 18:198-200
This case report describes the unusual condition of Lemierre's syndrome diagnosed in the first trimester of pregnancy. The diagnosis was made by ultrasound and magnetic resonance imaging. The patient was treated with intravenous antibiotics and was a
Autor:
Michelle Dixon, Nicola J. Curtin, Laura Woodhouse, San Soohoo, Aiste McCormick, Richard J. Edmondson, Angelika Kaufman, Ahmed Elattar, Madeleine Moat, Anna Grundy, Asima Mukhopadhyay, Rachel L. O′Donnell
Publikováno v:
PLoS ONE
PLoS ONE, Vol 9, Iss 6, p e90604 (2014)
PLoS ONE, Vol 9, Iss 6, p e90604 (2014)
The use of cell lines or animal models has significant disadvantages when dealing with a set of heterogeneous diseases such as epithelial ovarian cancer. This has clinical relevance in that biomarkers developed using cell line or animal models are of