Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Rachel L Fehrman"'
Publikováno v:
Cell Death and Disease, Vol 12, Iss 8, Pp 1-11 (2021)
Abstract Axonal degeneration of retinal ganglion cells (RGCs) causes blindness in glaucoma. Currently, there are no therapies that target axons to prevent them from degenerating. Activation of the BAX protein has been shown to be the determining step
Externí odkaz:
https://doaj.org/article/680aac1197894499b42cbfae53274c72
Publikováno v:
BMC Research Notes, Vol 14, Iss 1, Pp 1-7 (2021)
Abstract Objective Elamipretide (SS31) is a mitochondria-targeted peptide that has reported functions of stabilizing mitochondrial cristae structure and improving mitochondrial bioenergetics. Several studies have documented cell protective features o
Externí odkaz:
https://doaj.org/article/a0a3bdfe79184dedbcc355b0d9ece19c
Autor:
Amélie Vantaux, Michelle M. Riehle, Eakpor Piv, Elise J. Farley, Sophy Chy, Saorin Kim, Anneli G. Corbett, Rachel L. Fehrman, Anais Pepey, Karin Eiglmeier, Dysoley Lek, Sovannaroth Siv, Ivo Mueller, Kenneth D. Vernick, Benoit Witkowski
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-17 (2021)
Abstract In the Greater Mekong Subregion, malaria cases have significantly decreased but little is known about the vectors or mechanisms responsible for residual malaria transmission. We analysed a total of 3920 Anopheles mosquitoes collected during
Externí odkaz:
https://doaj.org/article/0269045c833d476d9a8093d6977299af
Autor:
Amélie Vantaux, Michelle M. Riehle, Eakpor Piv, Elise J. Farley, Sophy Chy, Saorin Kim, Anneli G. Corbett, Rachel L. Fehrman, Anais Pepey, Karin Eiglmeier, Dysoley Lek, Sovannaroth Siv, Ivo Mueller, Kenneth D. Vernick, Benoit Witkowski
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-2 (2021)
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Externí odkaz:
https://doaj.org/article/6aeff2ee8ac54504842eafbf2e47636d
Publikováno v:
Cell Death and Disease, Vol 12, Iss 8, Pp 1-11 (2021)
Axonal degeneration of retinal ganglion cells (RGCs) causes blindness in glaucoma. Currently, there are no therapies that target axons to prevent them from degenerating. Activation of the BAX protein has been shown to be the determining step in the i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c0563af65a86fea3ef865813a52b8e7
https://doaj.org/article/680aac1197894499b42cbfae53274c72
https://doaj.org/article/680aac1197894499b42cbfae53274c72
Publikováno v:
BMC Research Notes
BMC Research Notes, Vol 14, Iss 1, Pp 1-7 (2021)
BMC Research Notes, Vol 14, Iss 1, Pp 1-7 (2021)
Objective Elamipretide (SS31) is a mitochondria-targeted peptide that has reported functions of stabilizing mitochondrial cristae structure and improving mitochondrial bioenergetics. Several studies have documented cell protective features of this pe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b4af6c2b33b3bbc0d549b091141f275
https://doi.org/10.1186/s13104-021-05613-9
https://doi.org/10.1186/s13104-021-05613-9
Publikováno v:
Cell Death & Disease
Axonal degeneration of retinal ganglion cells (RGCs) causes blindness in glaucoma. Currently, there are no therapies that target axons to prevent them from degenerating. Activation of the BAX protein has been shown to be the determining step in the i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::16486af379655b0bde86ad8fc9aae3e4
https://pubmed.ncbi.nlm.nih.gov/34376637
https://pubmed.ncbi.nlm.nih.gov/34376637
Autor:
Benoit Witkowski, Anneli G Corbett, Karin Eiglmeier, Dysoley Lek, Michelle M. Riehle, Saorin Kim, Kenneth D. Vernick, Elise J Farley, Amélie Vantaux, Rachel L Fehrman, Sovannaroth Siv, Eakpor Piv, Ivo Mueller, Sophy Chy, Anais Pepey
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-2 (2021)
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb4f47bee9487015df59b16fabcb3e92
https://doaj.org/article/6aeff2ee8ac54504842eafbf2e47636d
https://doaj.org/article/6aeff2ee8ac54504842eafbf2e47636d
Autor:
Rachel L. Fehrman, Cassandra L. Schlamp, Lian-Wang Guo, Robert W. Nickells, Huan Yang, Margaret E. Maes, Heather R. Pelzel, Heather Schmitt
Publikováno v:
Investigative Ophthalmology & Visual Science
Purpose Inhibition or targeted deletion of histone deacetylase 3 (HDAC3) is neuroprotective in a variety neurodegenerative conditions, including retinal ganglion cells (RGCs) after acute optic nerve damage. Consistent with this, induced HDAC3 express
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c32e8d742aaa8c3dcb053dcba77597f4
https://doi.org/10.1167/iovs.62.10.14
https://doi.org/10.1167/iovs.62.10.14
Autor:
Cassandra L. Schlamp, Joshua A. Grosser, Robert W. Nickells, Margaret E. Maes, Rachel L. Fehrman
Publikováno v:
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-15 (2019)
Scientific Reports, Vol 9, Iss 1, Pp 1-15 (2019)
BAX, a member of the BCL2 gene family, controls the committed step of the intrinsic apoptotic program. Mitochondrial fragmentation is a commonly observed feature of apoptosis, which occurs through the process of mitochondrial fission. BAX has consist
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abdee5befd20fb7fd7b7587da7bd891e
https://doi.org/10.1038/s41598-019-53049-w
https://doi.org/10.1038/s41598-019-53049-w