Zobrazeno 1 - 10
of 137
pro vyhledávání: '"Rachel Krupa"'
Autor:
David Lu, Rachel Krupa, Melissa Harvey, Ryon P. Graf, Nicole Schreiber, Ethan Barnette, Emily Carbone, Adam Jendrisak, Audrey Gill, Sarah Orr, Howard I. Scher, Joseph Daniel Schonhoft
Publikováno v:
Journal of Circulating Biomarkers, Vol 9, Iss 1, Pp 13-19 (2020)
Introduction: Here we describe the development of a protein immunofluorescent assay for the detection of nuclear-localized androgen receptor variant 7 (AR-V7) protein within circulating tumor cells (CTCs) identified in patient blood samples. Used in
Externí odkaz:
https://doaj.org/article/f2fff97879a2482492016803266e8339
Autor:
Jorge Nieva, Ryan V. Dittamore, Lyudmila Bazhenova, Samir Makani, Marisa Magaña, Stephanie B. Greene, Mahipal Suraneni, Mark Landers, Yipeng Wang, Lyndsey Dugan, Jessica Louw, Rachel Krupa, David Lu, Jessica Hoag, Michelle C. Salazar, Ryon P. Graf, Daniel J. Boffa
Assessment of PD-L1 Assay Sensitivity and Specificity.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ee4a84903304748cde92695267aa7db
https://doi.org/10.1158/1055-9965.22436826
https://doi.org/10.1158/1055-9965.22436826
Autor:
Jorge Nieva, Ryan V. Dittamore, Lyudmila Bazhenova, Samir Makani, Marisa Magaña, Stephanie B. Greene, Mahipal Suraneni, Mark Landers, Yipeng Wang, Lyndsey Dugan, Jessica Louw, Rachel Krupa, David Lu, Jessica Hoag, Michelle C. Salazar, Ryon P. Graf, Daniel J. Boffa
Background: Lung cancer treatment has become increasingly dependent upon invasive biopsies to profile tumors for personalized therapy. Recently, tumor expression of programmed death-ligand 1 (PD-L1) has gained interest as a potential predictor of res
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25351a2a77e04e2326f7efe9f07e9334
https://doi.org/10.1158/1055-9965.c.6515595
https://doi.org/10.1158/1055-9965.c.6515595
Autor:
Howard I. Scher, Ryan Dittamore, Dena Marrinucci, Scott T. Tagawa, David M. Nanus, Nicole A. Schreiber, Ryon P. Graf, Rachel Krupa, Jessica Louw, Myriam Kossai, Juan Miguel Mosquera, Mark Landers, Adam Jendrisak, Himisha Beltran
Figure S1: Examples of a decision boundary that separate class A (red) from class B (blue) in 1 dimension (figure 1A) and 2 dimensions (figure 1B); Figure S2: Schematic of the supervised learning process (A) and leave one out cross validation (B); Fi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec9b853ef189603226c86b6b11fd33d9
https://doi.org/10.1158/1078-0432.22459598.v1
https://doi.org/10.1158/1078-0432.22459598.v1
Autor:
Ryan Dittamore, Glenn Heller, Mark Landers, Martin Fleisher, Hebert A. Vargas, Lyndsey Dugan, Jessica E. Louw, Pascal Bamford, David Lu, Rachel Krupa, Stephanie Greene, Jerry Lee, Yipeng Wang, Adam Jendrisak, Brigit McLaughlin, Nicole A. Schreiber, Ryon P. Graf, Howard I. Scher
The heterogeneity of an individual patient's tumor has been linked to treatment resistance, but quantitative biomarkers to rapidly and reproducibly evaluate heterogeneity in a clinical setting are currently lacking. Using established tools available
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1c402becdf1a2391aa635f0698de7c41
https://doi.org/10.1158/0008-5472.c.6509265.v1
https://doi.org/10.1158/0008-5472.c.6509265.v1
Autor:
Andrea B. Apolo, Donald P. Bottaro, Jane B. Trepel, John J. Wright, Howard Streicher, William L. Dahut, James L. Gulley, Carlos Diaz, Jacqueline Cadena, Rene Costello, Olena Sierra Ortiz, Marissa Mallek, Lisa Ley, Lisa M. Cordes, Seth M. Steinberg, David I. Quinn, Mark N. Stein, Primo N. Lara, Sumanta K. Pal, Ryan Dittamore, Yipeng Wang, Amanda K.L. Anderson, Rachel Krupa, Robin Richardson, Yen-Lin Chu, Adam Jendrisak, Joseph D. Schonhoft, Scot A. Niglio, Amir Mortazavi, Tiziano Pramparo, Heather J. Chalfin
Purpose:Circulating tumor cells (CTC) are under investigation as a minimally invasive liquid biopsy that may improve risk stratification and treatment selection. CTCs uniquely allow for digital pathology of individual malignant cell morphology and ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::016e605cd0aeda130b5f9a38740de745
https://doi.org/10.1158/1078-0432.c.6529986
https://doi.org/10.1158/1078-0432.c.6529986
Autor:
Howard I. Scher, Ryan Dittamore, Dena Marrinucci, Scott T. Tagawa, David M. Nanus, Nicole A. Schreiber, Ryon P. Graf, Rachel Krupa, Jessica Louw, Myriam Kossai, Juan Miguel Mosquera, Mark Landers, Adam Jendrisak, Himisha Beltran
Purpose: The transition of prostate adenocarcinoma to a predominantly androgen receptor (AR) signaling independent phenotype can occur in the later stages of the disease and is associated with low AR expression +/− the development of small-cell or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6437742746c507d642175adc86f3c0f9
https://doi.org/10.1158/1078-0432.c.6524261.v1
https://doi.org/10.1158/1078-0432.c.6524261.v1
Autor:
Jorge Nieva, Ryan V. Dittamore, Lyudmila Bazhenova, Samir Makani, Marisa Magaña, Stephanie B. Greene, Mahipal Suraneni, Mark Landers, Yipeng Wang, Lyndsey Dugan, Jessica Louw, Rachel Krupa, David Lu, Jessica Hoag, Michelle C. Salazar, Ryon P. Graf, Daniel J. Boffa
Cox Proportional Hazards Model of Patients With Confirmed Lung Cancer.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c9254637fad7da6fbf250f45aa9d200
https://doi.org/10.1158/1055-9965.22436817.v1
https://doi.org/10.1158/1055-9965.22436817.v1
Autor:
Takeo Fujii, James M Reuben, Lei Huo, Jose Rodrigo Espinosa Fernandez, Yun Gong, Rachel Krupa, Mahipal V Suraneni, Ryon P Graf, Jerry Lee, Stephanie Greene, Angel Rodriguez, Lyndsey Dugan, Jessica Louw, Bora Lim, Carlos H Barcenas, Angela N Marx, Debu Tripathy, Yipeng Wang, Mark Landers, Ryan Dittamore, Naoto T Ueno
Publikováno v:
PLoS ONE, Vol 12, Iss 9, p e0185231 (2017)
Androgen receptor (AR) is frequently detected in breast cancers, and AR-targeted therapies are showing activity in AR-positive (AR+) breast cancer. However, the role of AR in breast cancers is still not fully elucidated and the biology of AR in breas
Externí odkaz:
https://doaj.org/article/03d577abb63d4dd384a30274ba5974ae
Autor:
Rene Costello, William L. Dahut, Heather J. Chalfin, Seth M. Steinberg, David I. Quinn, Marissa Mallek, Jane B. Trepel, Ryan Dittamore, John Wright, Yipeng Wang, Robin Richardson, Adam Jendrisak, Jacqueline Cadena, James L. Gulley, Carlos Diaz, Tiziano Pramparo, Yen Lin Chu, Sumanta K. Pal, Rachel Krupa, Primo N. Lara, Olena Sierra Ortiz, Andrea B. Apolo, Howard Streicher, Amanda K. L. Anderson, Lisa M. Cordes, Donald P. Bottaro, Lisa Ley, Amir Mortazavi, Joseph D. Schonhoft, Mark N. Stein, Scot Anthony Niglio
Publikováno v:
Clinical Cancer Research. 27:1391-1398
Purpose: Circulating tumor cells (CTC) are under investigation as a minimally invasive liquid biopsy that may improve risk stratification and treatment selection. CTCs uniquely allow for digital pathology of individual malignant cell morphology and m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1e8a603ac4ae9dd11cd62a3b9bcc25e5
https://doi.org/10.1158/1078-0432.ccr-20-2891
https://doi.org/10.1158/1078-0432.ccr-20-2891