Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Rachel Kalifa"'
Autor:
Yehuda Schlesinger, Oshri Yosefov-Levi, Dror Kolodkin-Gal, Roy Zvi Granit, Luriano Peters, Rachel Kalifa, Lei Xia, Abdelmajeed Nasereddin, Idit Shiff, Osher Amran, Yuval Nevo, Sharona Elgavish, Karine Atlan, Gideon Zamir, Oren Parnas
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-18 (2020)
Pancreatic ductal adenocarcinoma may be initiated by acinar metaplasia, but the molecular and cellular insights during this transition are unclear. Here the authors show, using single cell RNA-sequencing analyses, that mouse metaplastic acinar cells
Externí odkaz:
https://doaj.org/article/9ac32cd2b6ea40c9ae2b5bb608e74f22
Publikováno v:
Biological Procedures Online, Vol 22, Iss 1, Pp 1-12 (2020)
Abstract Background The generation of point mutations is a major tool for evaluating the roles of specific nucleotides or amino acids within the regulatory or functional landscape. However, examination of these mutations in vivo requires the generati
Externí odkaz:
https://doaj.org/article/f1eb982ce9334387966cd2bf74d56506
Autor:
Tikva Shore, Tgst Levi, Rachel Kalifa, Amatzia Dreifuss, Dina Rekler, Ariella Weinberg-Shukron, Yuval Nevo, Tzofia Bialistoky, Victoria Moyal, Merav Yaffa Gold, Shira Leebhoff, David Zangen, Girish Deshpande, Offer Gerlitz
Publikováno v:
eLife, Vol 11 (2022)
We recently identified a missense mutation in Nucleoporin107 (Nup107; D447N) underlying XX-ovarian-dysgenesis, a rare disorder characterized by underdeveloped and dysfunctional ovaries. Modeling of the human mutation in Drosophila or specific knockdo
Externí odkaz:
https://doaj.org/article/d56caaf475a2444e90d005ff813696b5
Autor:
Tgst Levi, Tikva Shore, Rachel Kalifa, Amatzia Dreifuss, Dina Rekler, Ariella Weinberg-Shukron, Yuval Nevo, Tzofia Bialistoky, Victoria Moyal, Merav Yaffa Gold, Shira Leebhoff, David Zangen, Girish Deshpande, Offer Gerlitz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e69cc70443d29dbf57bc0e223c673f8a
https://doi.org/10.7554/elife.72632.sa2
https://doi.org/10.7554/elife.72632.sa2
Autor:
Areej Khatib, Lior Roitman, Sharona Elgavish, Narmen Azazmeh, Anna Hochner-Ger, Eli Pikarsky, Gideon Zamir, Rachel Kalifa, Benjamin Assouline, Jonathan Demma, Yonatan Khalatnik, Yehuda Schlesinger, Yuval Dor, Karen Meir, Hadar Benyamini, Valery Krizhanovsky, Oren Parnas, Ittai Ben-Porath, Shaul Horwitz, Ashraf Imam, Karine Atlan, Yossi Ovadya, Dror Kolodkin-Gal, Eitan Winter
Publikováno v:
Gut
ObjectiveCellular senescence limits tumourigenesis by blocking the proliferation of premalignant cells. Additionally, however, senescent cells can exert paracrine effects influencing tumour growth. Senescent cells are present in premalignant pancreat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0a12fc182e78c3ef7e9cf5108dda518
Autor:
Luriano Peters, Osher Amran, Lei Xia, Dror Kolodkin-Gal, Roy Zvi Granit, Abdelmajeed Nasereddin, Oshri Yosefov-Levi, Idit Shiff, Gideon Zamir, Karine Atlan, Yehuda Schlesinger, Rachel Kalifa, Yuval Nevo, Oren Parnas, Sharona Elgavish
Publikováno v:
Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-18 (2020)
Nature Communications, Vol 11, Iss 1, Pp 1-18 (2020)
Acinar metaplasia is an initial step in a series of events that can lead to pancreatic cancer. Here we perform single-cell RNA-sequencing of mouse pancreas during the progression from preinvasive stages to tumor formation. Using a reporter gene, we i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b8a1c772152a7cad04f1422f05a950a
https://doi.org/10.1038/s41467-020-18207-z
https://doi.org/10.1038/s41467-020-18207-z
Publikováno v:
Cellular Signalling. 36:117-126
T cell receptor (TCR) recognition of a peptide antigen in the context of MHC molecules initiates positive and negative cascades that regulate T cell activation, proliferation and differentiation, and culminate in the acquisition of effector T cell fu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::685306058a2c25255fe27e011e528d17
https://doi.org/10.1016/j.cellsig.2017.04.022
https://doi.org/10.1016/j.cellsig.2017.04.022
Autor:
Sharon Zeligson, Ephrat Levy-Lahad, Orit Lobel, Ariella Weinberg-Shukron, Michal Goldberg, Mary-Claire King, David Zangen, Tikva Shore, Mariana Rachmiel, Paul Renbaum, Suleyman Gulsuner, Rachel Kalifa, Offer Gerlitz, Amatzia Dreifuss, Tom Walsh, Avital Ben-Moshe, Reeval Segel
Publikováno v:
Yearbook of Paediatric Endocrinology.
The causes of ovarian dysgenesis remain incompletely understood. Two sisters with XX ovarian dysgenesis carried compound heterozygous truncating mutations in the BRCA2 gene that led to reduced BRCA2 protein levels and an impaired response to DNA dama
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ef06552f86c30d40f9f9abea232faed
https://doi.org/10.1530/ey.16.6.4
https://doi.org/10.1530/ey.16.6.4
Functional analysis of Niemann-Pick disease type C family protein, NPC1a, in Drosophila melanogaster
Autor:
Paul Schedl, Diane Manry, Girish Deshpande, Rachel Kalifa, Victoria Moyal, Christopher Ng, Offer Gerlitz, Sol Zamir, Yunah Kim, Peyton Smith, Tzofia Bialistoky
Publikováno v:
Development. 146
During embryonic gonad coalescence, primordial germ cells (PGCs) follow a carefully choreographed migratory route circumscribed by guidance signals towards somatic gonadal precursor cells (SGPs). In Drosophila melanogaster, SGP-derived Hedgehog (Hh),
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5e0b355a70f59efdaa93b2b21474c8a9
https://doi.org/10.1242/dev.168427
https://doi.org/10.1242/dev.168427
Autor:
Tzofia, Bialistoky, Diane, Manry, Peyton, Smith, Christopher, Ng, Yunah, Kim, Sol, Zamir, Victoria, Moyal, Rachel, Kalifa, Paul, Schedl, Offer, Gerlitz, Girish, Deshpande
Publikováno v:
Development
During embryonic gonad coalescence, primordial germ cells (PGCs) follow a carefully choreographed migratory route circumscribed by guidance signals towards somatic gonadal precursor cells (SGPs). In Drosophila melanogaster, SGP-derived Hedgehog (Hh),
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5cd054c179f05b95410eb9591db6a518
https://pubmed.ncbi.nlm.nih.gov/31092503
https://pubmed.ncbi.nlm.nih.gov/31092503