Zobrazeno 1 - 10
of 103
pro vyhledávání: '"Rachel K. Hoyles"'
Autor:
Toby M Maher, Veronica A Tudor, Peter Saunders, Fernando Zanghelini, Carlota Grossi Sampedro, Georgios Xydopoulos, Michael Gibbons, Sophie V Fletcher, Christopher P Denton, Maria Kokosi, Rachel K Hoyles, Helen Parfrey, Elisabetta A Renzoni, Athol U Wells, Deborah Ashby, Richard J Fordham, Matyas Szigeti, Philip L Molyneaux
Publikováno v:
Efficacy and Mechanism Evaluation, Vol 11, Iss 04 (2024)
Background Interstitial lung disease frequently complicates systemic autoimmune disorders including scleroderma, idiopathic inflammatory myositis and mixed connective tissue disease, resulting in considerable morbidity and mortality. Based on the res
Externí odkaz:
https://doaj.org/article/e6fce1fb145949bfbbfaa25f5a601c57
Publikováno v:
BMJ Open Respiratory Research, Vol 10, Iss 1 (2023)
Background Idiopathic pulmonary fibrosis (IPF) is a progressive fibrotic lung disease with poor prognosis. Clinical studies have demonstrated association between different blood leucocytes and mortality and forced vital capacity (FVC) decline. Here,
Externí odkaz:
https://doaj.org/article/43f9a5fe74eb4316bfd032ab260161fc
Autor:
Emma Derrett-Smith, Kristina E. N. Clark, Xu Shiwen, David J. Abraham, Rachel K. Hoyles, Olivier Lacombe, Pierre Broqua, Jean Louis Junien, Irena Konstantinova, Voon H. Ong, Christopher P. Denton
Publikováno v:
Arthritis Research & Therapy, Vol 23, Iss 1, Pp 1-13 (2021)
Abstract Background The TβRII∆k-fib transgenic (TG) mouse model of scleroderma replicates key fibrotic and vasculopathic complications of systemic sclerosis through fibroblast-directed upregulation of TGFβ signalling. We have examined peroxisome
Externí odkaz:
https://doaj.org/article/29917a595917451aa674f32d4bacb9c8
Neutrophil lymphocyte ratio as an indicator for disease progression in Idiopathic Pulmonary Fibrosis
Autor:
Ling-Pei Ho, Rosie Barker, Harriet Bothwell, Andrea Pereira, Rachel K Hoyles, Rachel Benamore, Kritica Dwivedi, Andrew Achaiah, Amila Rathnapala, Valentina Iotchkova
Publikováno v:
BMJ Open Respiratory Research, Vol 9, Iss 1 (2022)
Rationale Idiopathic pulmonary fibrosis (IPF) is a progressive fibrotic lung disease. Patients present at different stages and disease course is varied. Blood monocytes have been linked to all-cause mortality, and neutrophils to progression to IPF in
Externí odkaz:
https://doaj.org/article/84320416701d4b0594b9a41ecaa34f6a
Autor:
Ling-Pei Ho, Rosie Barker, Harriet Bothwell, Andrea Pereira, Rachel K Hoyles, Rachel Benamore, Kritica Dwivedi, Amila Rathnapala, Valentina Iotchkova
Publikováno v:
BMJ Open Respiratory Research, Vol 8, Iss 1 (2021)
Externí odkaz:
https://doaj.org/article/dce566b922b941ad9e06c582b3f2ff29
Publikováno v:
BMJ Open Respiratory Research, Vol 7, Iss 1 (2020)
Introduction There is currently no readily accessible measure to specifically quantify the amount of fibrosis in idiopathic pulmonary fibrosis (IPF). Such a measure could isolate contribution of fibrosis from other comorbidities to lung function abno
Externí odkaz:
https://doaj.org/article/b4fb98c5e0204359801f622f9ed294d9
Publikováno v:
BMJ Open Respiratory Research, Vol 7, Iss 1 (2020)
Externí odkaz:
https://doaj.org/article/da56f3f039764b9d84e0359df2c0c683
Publikováno v:
BMJ Open Respiratory Research, Vol 7, Iss 1 (2020)
Externí odkaz:
https://doaj.org/article/7172e62918bf4ee4a74ff390304e9292
Publikováno v:
BMJ Open Respiratory Research, Vol 7, Iss 1 (2020)
Externí odkaz:
https://doaj.org/article/bf68d4d299764700b3b1430853b66fe2
Publikováno v:
BMJ Open Respiratory Research, Vol 7, Iss 1 (2020)
Externí odkaz:
https://doaj.org/article/09ed386774d64ca1bbf91d48b41760a6