Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Rachel K. Chambers"'
Publikováno v:
Advanced synthesiscatalysis. 362(2)
Aromatic and heterocyclic functionality are ubiquitous in pharmaceuticals. Herein, we disclose a new Mn(PDP)catalyst system using chloroacetic acid additive capable of chemoselectively oxidizing remote tertiary C(sp(3))—H bonds in the presence of a
Autor:
Rachel K. Chambers, Stephen G. Pyne, Thanaphat Thaima, Nattapong Chaipukdee, Kwanjai Kanokmedhakul
Publikováno v:
European Journal of Organic Chemistry. 2016:3765-3772
The three component borono-Mannich reactions of ethyl glyoxylate, primary or secondary amines and pinacol allenylboronate or potassium allenyltrifluoroborate are highly regioselective and give α-propargylglycinates. The (S)-N-tert-butylsulfinyl imin
Publikováno v:
Organic & Biomolecular Chemistry. 14:4970-4985
Aspartyl proteases are important pharmacological targets. Historically aspartyl proteases have been commonly targeted with transition state derived peptidomimetics. The strategy to develop aspartyl protease inhibitors has undertaken a dramatic paradi
Publikováno v:
ChemInform. 47
Aspartyl proteases are important pharmacological targets. Historically aspartyl proteases have been commonly targeted with transition state derived peptidomimetics. The strategy to develop aspartyl protease inhibitors has undertaken a dramatic paradi