Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Rachel J. Moser"'
Autor:
Aaron Martin, Jeff Smith, Matthew L. Hirsch, Rachel J. Moser, Jo Ann Hux, Clayton W. Beard, Bruce J. Mccreedy, Melissa A. Triggiano, Daniel T. MacLeod, Victor V. Bartsevich, Michael G. Nicholson, Caitlin Turner, Audrey E. Brown, Christina D. Pham, Samantha Kirkland, Janel Lape, Armin Hekele, Jeyaraj Antony, Derek Jantz, Keith J. Wetzel
Publikováno v:
Molecular Therapy
Adoptive cellular therapy using chimeric antigen receptor (CAR) T cell therapies have produced significant objective responses in patients with CD19+ hematological malignancies, including durable complete responses. Although the majority of clinical
Publikováno v:
Molecular Biology of the Cell
Actin-based protrusions are important for signaling and migration during development and homeostasis. Gain- and loss-of-function and quantitative approaches are used to define differential roles for the actin elongation factors Diaphanous and Enabled
Autor:
Matthew L. Hirsch, Rachel J. Moser
Publikováno v:
Current gene therapy. 16(3)
Recent work both at the bench and the bedside demonstrate zinc-finger nucleases (ZFNs), CRISPR/Cas9, and other programmable site-specific endonuclease technologies are being successfully utilized within and alongside AAV vectors to induce therapeutic
Publikováno v:
Advances in Experimental Medicine and Biology ISBN: 9781493935079
Recent advancements in mammalian genome editing technologies have demonstrated precise genetic manipulations at the chromosomal level at efficiencies relevant for disease therapy. In fact, zinc-finger nucleases (ZFNs) that induce deletions in the HIV
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cda550c0285739d077abaa45adc18c0d
https://doi.org/10.1007/978-1-4939-3509-3_8
https://doi.org/10.1007/978-1-4939-3509-3_8
Autor:
Rachel J. Moser, Daniel T. MacLeod, Jo Ann Hux, Jeff Smith, Audrey E. Brown, Caitlin Turner, Janel Lape, Jeyaraj Antony, Victor V. Bartsevich, Derek Jantz, Keith J. Wetzel, Michael Nicholson, Armin Hekele, Bruce J. Mccreedy, Clayton W. Beard, Matthew L. Hirsch
Publikováno v:
Molecular Therapy. 24:S156
Chimeric antigen receptor (CAR) T cell therapies have achieved dramatic results treating hematological malignancies by redirecting the specificity of T cells to target CD19 expressing cancer cells. Clinical trials reporting these impressive results h