Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Rachel J. Donahue"'
Autor:
Catherine J. Choi, Rahel Kastli, William A. Carlezon, John W. Muschamp, Uwe Rudolph, Rachel J. Donahue, Takao K. Hensch, Nathaniel Hodgson, Rebecca S. Benham, Nishani B. Hewage, Elif Engin
Publikováno v:
Neuropsychopharmacology
Brain α2-containing GABA(A) receptors play a critical role in the modulation of anxiety- and fear-like behavior. However, it is unknown whether these receptors also play a role in modulating resilience to chronic stress, and in which brain areas and
Publikováno v:
PLoS ONE, Vol 6, Iss 12, p e27797 (2011)
Much research has focused on how the amygdala processes individual affects, yet little is known about how multiple types of positive and negative affects are encoded relative to one another at the single-cell level. In particular, it is unclear wheth
Externí odkaz:
https://doaj.org/article/cd44928cb36a471bada73b2477709cfc
Autor:
Shunsuke Takagi, Jack Bergman, Matthew D. Puhl, Rajeev I. Desai, Michelle R Doyle, Joseph T. Coyle, Kendall Taylor Presti, William A. Carlezon, Rachel J. Donahue, Samantha M. Landino
Publikováno v:
Addiction Biology. 24:40-50
Both schizophrenia (SZ) and substance abuse (SA) exhibit significant heritability. Moreover, N-methyl-d-aspartate receptors (NMDARs) have been implicated in the pathophysiology of both SZ and SA. We hypothesize that the high prevalence of comorbid SA
Autor:
Rachel J. Donahue, Samantha M. Landino, William A. Carlezon, Sam A. Golden, Scott J. Russo, F. Ivy Carroll
Publikováno v:
Behavioural Pharmacology. 26:654-663
Accumulating evidence indicates that kappa-opioid receptors (KORs) and their endogenous ligand, dynorphin (DYN), can play important roles in regulating the effects of stress. Here, we examined the role of KOR systems in the molecular and behavioral e
Publikováno v:
Biological Psychiatry. 76:550-558
Background Chronic social defeat stress (CSDS) produces persistent behavioral adaptations in mice. In many behavioral assays, it can be difficult to determine if these adaptations reflect core signs of depression. We designed studies to characterize
Autor:
Matthew D, Puhl, Rajeev I, Desai, Shunsuke, Takagi, Kendall T, Presti, Michelle R, Doyle, Rachel J, Donahue, Samantha M, Landino, Jack, Bergman, William A, Carlezon, Joseph T, Coyle
Publikováno v:
Addiction biology. 24(1)
Both schizophrenia (SZ) and substance abuse (SA) exhibit significant heritability. Moreover, N-methyl-d-aspartate receptors (NMDARs) have been implicated in the pathophysiology of both SZ and SA. We hypothesize that the high prevalence of comorbid SA
Pituitary adenylate cyclase-activating polypeptide (PACAP) is implicated in stress regulation and learning and memory. PACAP has neuromodulatory actions on brain structures within the limbic system that could contribute to its acute and persistent ef
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cb91d090a1ecca567331e668b6718f5
https://europepmc.org/articles/PMC4698186/
https://europepmc.org/articles/PMC4698186/
Publikováno v:
Addiction Biology. 17:309-321
The α4βδ gamma-aminobutyric acid A receptor (GABAAR) has been proposed to mediate the rewarding effects of low-to-moderate concentrations of alcohol (ethanol) that approximate those achieved by social drinking. If this is true, then this receptor
Publikováno v:
Annals of the New York Academy of Sciences. 1121:216-231
It has been proposed that long-term declarative memories are ultimately stored through interactions between the hippocampal memory system and the neocortical association areas that initially processed the to-be-stored information. One association neo
Autor:
Josephine Lee, Rachel J. Donahue, D Foti, Courtney Beard, Daniel G. Dillon, A. Van't Veer, Kean J. Hsu, F I Carroll, Thröstur Björgvinsson, Diego A. Pizzagalli, Elyssa M. Barrick, Chelsea J Webber, William A. Carlezon
Publikováno v:
Translational Psychiatry
Depression has been associated with poor performance following errors, but the clinical implications, response to treatment and neurobiological mechanisms of this post-error behavioral adjustment abnormality remain unclear. To fill this gap in knowle