Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Rachel J. A. Helliwell"'
Autor:
Roberto Romero, Murray D. Mitchell, Maxwell C. Chang, Timothy A. Sato, Hao-Yi Lan, Rachel J. A. Helliwell, Tinnakorn Chaiworapongsa
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 90:4244-4248
Context: 9α,11β-Prostaglandin F2 (9α,11β-PGF2) can contract uterine smooth muscle with a potency equal to PGF2α. Its presence in the human uterus and production by human gestational tissues is unknown.Objective: These studies were performed to d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1f40a8eec965b15ab507d8f7bf04bf8
https://doi.org/10.1210/jc.2004-2496
https://doi.org/10.1210/jc.2004-2496
Autor:
Murray D. Mitchell, Timothy A. Sato, Elicia B.E Berry, Rachel J. A. Helliwell, R. Stewart Gilmour
Publikováno v:
Prostaglandins, Leukotrienes and Essential Fatty Acids. 71:191-197
Cyclopentenone prostaglandins, Delta(12)-PGJ(2) and 15d-PGJ(2), have potent anti-tumour and anti-inflammatory activities, and have been shown to induce apoptosis in amnion-derived WISH cells. In this study, we have investigated the protective effects
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a10ba34b2013273880a1cf0d9994122
https://doi.org/10.1016/j.plefa.2004.04.001
https://doi.org/10.1016/j.plefa.2004.04.001
Publikováno v:
Prostaglandins, Leukotrienes and Essential Fatty Acids. 70:149-165
The key regulatory role of prostanoids [prostaglandins (PGs) and thromboxanes (TXs)] in the maintenance of pregnancy and initiation of parturition has been established [1-3]. However, our understanding of how these events are fine-tuned by the recrui
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98d7409bb4eb38211adf3252b73de0cb
https://doi.org/10.1016/j.plefa.2003.04.005
https://doi.org/10.1016/j.plefa.2003.04.005
Publikováno v:
Prostaglandins, Leukotrienes and Essential Fatty Acids. 70:101-113
Cells are continuously exposed to cues, which signal cell survival or death. Fine-tuning of these conflicting signals is essential for tissue development and homeostasis, and defective pathways are linked to many disease processes, especially cancer.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3e46c75925fb62aa0987cdba229eb28
https://doi.org/10.1016/j.plefa.2003.04.002
https://doi.org/10.1016/j.plefa.2003.04.002
Autor:
R. Stewart Gilmour, K.W. Marvin, Elicia B.E Berry, R.L. Eykholt, Murray D. Mitchell, Rachel J. A. Helliwell
Publikováno v:
Molecular Pharmacology. 64:1586-1590
Peroxisome proliferator-activated receptors (PPARs) are a family of nuclear receptors that are involved in lipid metabolism, differentiation, proliferation, cell death, and inflammation. Three subtypes have been identified: PPAR-alpha, -delta, and -g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa4a86ff71c7844539874ce3d150a0cf
https://doi.org/10.1124/mol.64.6.1586
https://doi.org/10.1124/mol.64.6.1586
Autor:
Elicia B. E. Berry, K.W. Marvin, R. Stewart Gilmour, Bianca E. Nijmeijer, Jeffrey A. Keelan, Murray D. Mitchell, Rachel J. A. Helliwell, Timothy A. Sato
Publikováno v:
Prostaglandins & Other Lipid Mediators. 66:265-282
Apoptosis at the site of rupture has been proposed to play a role in premature rupture of the fetal membranes, a condition associated with increased risk of neonatal sepsis and preterm birth. We investigated the ability of peroxisome proliferator-act
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1609a0fcd8e6346ddd268afaaf7bcbf
https://doi.org/10.1016/s0090-6980(01)00164-2
https://doi.org/10.1016/s0090-6980(01)00164-2
Autor:
Rachel J. A. Helliwell, Mhoyra Fraser, Scott‘ W. Wells, Terrie E. Inder, Laura Bennet, Alistair J. Gunn, Peter D. Gluckman, Chris E. Williams
Publikováno v:
Reproductive sciences (Thousand Oaks, Calif.). 14(2)
Early and accurate evaluation of the nature and extent of cerebral injury in the preterm infant brain is important for prognostication and decision making in the neonatal intensive care unit. The capability of magnetic resonance imaging (MRI) to defi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89c99d87f2a38fc5793a828440140e99
https://pubmed.ncbi.nlm.nih.gov/17636230
https://pubmed.ncbi.nlm.nih.gov/17636230
Autor:
Roberto Romero, Timothy A. Sato, Linda Adams, Maxwell C. Chang, Simon J. O'Carroll, Jeffrey Keelan, Tinnakorn Chaiworapongsa, Rachel J. A. Helliwell, Murray D. Mitchell, Ashmit Anand, K.W. Marvin
Publikováno v:
The Journal of clinical endocrinology and metabolism. 91(2)
The importance of prostaglandin (PG) signaling pathways to the maintenance of pregnancy and initiation of labor is well recognized. However, the complexity of these pathways and the mechanism(s) of their coordinated regulation in physiological and pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da3ea5779ca0719ee40e77a9a5bbfb5a
https://pubmed.ncbi.nlm.nih.gov/16291703
https://pubmed.ncbi.nlm.nih.gov/16291703
Autor:
Elicia B. E. Berry, R. Stewart Gilmour, Rachel J. A. Helliwell, Murray D. Mitchell, Jeffrey A. Keelan
Publikováno v:
Molecular pharmacology. 68(1)
15-Deoxy delta(12,14)-prostaglandin J(2) (15d-PGJ(2)), an activator of peroxisome proliferator-activated receptor (PPAR)-gamma and -delta, is a prostanoid metabolite with anti-inflammatory actions. In intrauterine tissues, proinflammatory cytokines a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2e0bf27f75172b20705086bbcda1cc6
https://pubmed.ncbi.nlm.nih.gov/15821150
https://pubmed.ncbi.nlm.nih.gov/15821150
Autor:
Lawrence W. Chamley, Michelle Glass, Murray D. Mitchell, Katherine Blake-Palmer, Janice Wu, Rachel J. A. Helliwell, Christopher S. Kearn
Publikováno v:
The Journal of clinical endocrinology and metabolism. 89(10)
In recent years, it has been demonstrated that high circulating levels of the endogenous cannabinoid anandamide, resulting from low expression of its metabolizing enzyme fatty acid amide hydrolase (FAAH), may contribute to spontaneous miscarriage and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3d88bb09b0acf14115df81ea5365a94
https://pubmed.ncbi.nlm.nih.gov/15472222
https://pubmed.ncbi.nlm.nih.gov/15472222