Zobrazeno 1 - 10
of 100
pro vyhledávání: '"Rachel J Waddington"'
Autor:
Arooj Munir, Anne Døskeland, Steven J Avery, Tiziana Fuoco, Samih Mohamed-Ahmed, Henning Lygre, Anna Finne-Wistrand, Alastair J Sloan, Rachel J Waddington, Kamal Mustafa, Salwa Suliman
Publikováno v:
Journal of Tissue Engineering, Vol 10 (2019)
Poly(L-lactide-co-ε-caprolactone) scaffolds were functionalised by 10 or 20 µg/mL of human demineralised dentine matrix. Release kinetics up to 21 days and their osteogenic potential on human bone marrow stromal cells after 7 and 21 days were studi
Externí odkaz:
https://doaj.org/article/10b045a681bc4d57b200b6ff1db680f4
Publikováno v:
Journal of Tissue Engineering, Vol 6 (2015)
Bioactive growth factors identified within the extracellular matrix of dentine have been proposed roles in regulating the naturally inherent regenerative dentine formation seen in teeth in response to trauma and infection, which may also be harnessed
Externí odkaz:
https://doaj.org/article/eec066d616634bf796a0336390ba111d
Publikováno v:
Frontiers in Dental Medicine, Vol 4 (2023)
IntroductionBone has a high capacity for repair, but for patients with uncontrolled type 2 diabetes mellitus (T2DM), the associated hyperglycemia can significantly delay osteogenic processes. These patients respond poorly to fracture repair and bone
Externí odkaz:
https://doaj.org/article/2633520d04654f70a919d9192a4afba7
Publikováno v:
Stem Cell Research & Therapy, Vol 12, Iss 1, Pp 1-19 (2021)
Abstract Background Dental pulp stem cells (DPSCs) are increasingly being advocated as viable cell sources for regenerative medicine-based therapies. However, significant heterogeneity in DPSC expansion and multi-potency capabilities are well-establi
Externí odkaz:
https://doaj.org/article/962248b885f947059fabb6c3dc01b8ff
Autor:
Zi Y. Kok, Nadia Y. A. Alaidaroos, Amr Alraies, John S. Colombo, Lindsay C. Davies, Rachel J. Waddington, Alastair J. Sloan, Ryan Moseley
Publikováno v:
Stem Cells International, Vol 2022 (2022)
Human dental pulp stem/stromal cells (hDPSCs) derived from the permanent secondary dentition are recognised to possess certain advantageous traits, which support their potential use as a viable source of mesenchymal stem/stromal cells (MSCs) for rege
Externí odkaz:
https://doaj.org/article/6286b3f5f0df4f84bbef2dc42bff4c8c
Publikováno v:
Stem Cells International, Vol 2021 (2021)
Mobilization of naïve bone marrow mesenchymal stromal cells (BMSCs) is crucial to desired bone regeneration in both orthopedic and dental contexts. In such conditions, mesenchymal progenitor cell populations from human exfoliated deciduous teeth (SH
Externí odkaz:
https://doaj.org/article/c22d0c75f95845d9b43afdf1a482f6fa
Autor:
Ryan Moseley, Rachel J. Waddington
Publikováno v:
Free Radical Research. 55:970-981
Reactive oxygen species (ROS) overproduction and oxidative stress are increasingly being implicated in the extracellular matrix (ECM) degradation associated with chronic inflammatory conditions, such as periodontal diseases. The present study investi
Autor:
Norhayati Yusop, Paul Battersby, Amr Alraies, Alastair J. Sloan, Ryan Moseley, Rachel J. Waddington
Publikováno v:
Stem Cells International, Vol 2018 (2018)
Within bone, mesenchymal stromal cells (MSCs) exist within the bone marrow stroma (BM-MSC) and the endosteal niche, as cells lining compact bone (CB-MSCs). This study isolated and characterised heterogeneous MSC populations from each niche and subseq
Externí odkaz:
https://doaj.org/article/36c5f226033f4c71bb66ce9a3060dfdc
Publikováno v:
Frontiers in Dental Medicine
Mesenchymal stromal cells (MSCs) have long been the focus for regenerative medicine and the restoration of damaged or aging cells throughout the body. However, the efficacy of MSCs in cell-based therapy still remains unpredictable and carries with it
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b852e31ed82026b2b724064c0b172ef5
https://orca.cardiff.ac.uk/id/eprint/148529/1/fdmed-03-849724.pdf
https://orca.cardiff.ac.uk/id/eprint/148529/1/fdmed-03-849724.pdf
Autor:
Fraser I. Young, Vsevolod Telezhkin, Sarah J. Youde, Martin S. Langley, Maria Stack, Paul J. Kemp, Rachel J. Waddington, Alastair J. Sloan, Bing Song
Publikováno v:
Stem Cells International, Vol 2016 (2016)
Cellular heterogeneity presents an important challenge to the development of cell-based therapies where there is a fundamental requirement for predictable and reproducible outcomes. Transplanted Dental Pulp Stem/Progenitor Cells (DPSCs) have demonstr
Externí odkaz:
https://doaj.org/article/6509d82a57d045c7a208ed29b28e0525