Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Rachel J Lundie"'
Publikováno v:
Clinical & Translational Immunology, Vol 8, Iss 11, Pp n/a-n/a (2019)
Externí odkaz:
https://doaj.org/article/f23f481e00d841b7b0519452d8bada7b
Autor:
Anna M Hoy, Rachel J Lundie, Alasdair Ivens, Juan F Quintana, Norman Nausch, Thorsten Forster, Frances Jones, Narcis B Kabatereine, David W Dunne, Francisca Mutapi, Andrew S Macdonald, Amy H Buck
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 8, Iss 2, p e2701 (2014)
MicroRNAs (miRNAs) are a class of short non-coding RNA that play important roles in disease processes in animals and are present in a highly stable cell-free form in body fluids. Here, we examine the capacity of host and parasite miRNAs to serve as t
Externí odkaz:
https://doaj.org/article/b794d4cab0984b058bee5ee827781f68
Autor:
Catherine Q Nie, Nicholas J Bernard, M Ursula Norman, Fiona H Amante, Rachel J Lundie, Brendan S Crabb, William R Heath, Christian R Engwerda, Michael J Hickey, Louis Schofield, Diana S Hansen
Publikováno v:
PLoS Pathogens, Vol 5, Iss 4, p e1000369 (2009)
Plasmodium falciparum malaria causes 660 million clinical cases with over 2 million deaths each year. Acquired host immunity limits the clinical impact of malaria infection and provides protection against parasite replication. Experimental evidence i
Externí odkaz:
https://doaj.org/article/2e622cd804274a089953399cf44f4366
Autor:
Alice H. Costain, Alexander T. Phythian-Adams, Stefano A. P. Colombo, Angela K. Marley, Christian Owusu, Peter C. Cook, Sheila L. Brown, Lauren M. Webb, Rachel J. Lundie, Jessica G. Borger, Hermelijn H. Smits, Matthew Berriman, Andrew S. MacDonald
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/f40c387517a24427bc98e66dd0734278
Autor:
Alice H. Costain, Alexander T. Phythian-Adams, Stefano A. P. Colombo, Angela K. Marley, Christian Owusu, Peter C. Cook, Sheila L. Brown, Lauren M. Webb, Rachel J. Lundie, Jessica G. Borger, Hermelijn H. Smits, Matthew Berriman, Andrew S. MacDonald
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Schistosomiasis is a disease of global significance, with severity and pathology directly related to how the host responds to infection. The immunological narrative of schistosomiasis has been constructed through decades of study, with researchers of
Externí odkaz:
https://doaj.org/article/a17dd1fb55d94caead4e94f6c0c5976b
Different Life Cycle Stages of Plasmodium falciparum Induce Contrasting Responses in Dendritic Cells
Autor:
Xi Zen Yap, Rachel J. Lundie, Gaoqian Feng, Joanne Pooley, James G. Beeson, Meredith O'Keeffe
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Dendritic cells are key linkers of innate and adaptive immunity. Efficient dendritic cell activation is central to the acquisition of immunity and the efficacy of vaccines. Understanding how dendritic cells are affected by Plasmodium falciparum blood
Externí odkaz:
https://doaj.org/article/e129417a34b745ab9acea62adbc586d2
Autor:
Alexander T. Phythian-Adams, Alice H. Costain, Angela K. Marley, Sheila Brown, Lucy H. Jackson-Jones, Hermelijn H. Smits, Andrew S. MacDonald, Peter C. Cook, Josephine Forde-Thomas, Karl F. Hoffmann, Lauren M. Webb, Elia D. Tait Wojno, Rachel J. Lundie
Publikováno v:
Immunohorizons
Webb, L M, Phythian-adams, A T, Costain, A H, Brown, S L, Lundie, R J, Forde-thomas, J, Cook, P C, Jackson-jones, L H, Marley, A K, Smits, H H, Hoffmann, K F, Tait Wojno, E D & Macdonald, A S 2021, ' Plasmacytoid Dendritic Cells Facilitate Th Cell Cytokine Responses throughout Schistosoma mansoni Infection ', ImmunoHorizons, vol. 5, no. 8, pp. 721-732 . https://doi.org/10.4049/immunohorizons.2100071
Webb, L M, Phythian-adams, A T, Costain, A H, Brown, S L, Lundie, R J, Forde-thomas, J, Cook, P C, Jackson-jones, L H, Marley, A K, Smits, H H, Hoffmann, K F, Tait Wojno, E D & Macdonald, A S 2021, ' Plasmacytoid Dendritic Cells Facilitate Th Cell Cytokine Responses throughout Schistosoma mansoni Infection ', ImmunoHorizons, vol. 5, no. 8, pp. 721-732 . https://doi.org/10.4049/immunohorizons.2100071
Plasmacytoid dendritic cells (pDCs) are potent producers of type I IFN (IFN-I) during viral infection and respond to IFN-I in a positive feedback loop that promotes their function. IFN-I shapes dendritic cell responses during helminth infection, impa
Publikováno v:
Frontiers in Microbiology, Vol 11 (2020)
Severe malaria anemia is one of the most common causes of morbidity and mortality arising from infection with Plasmodium falciparum. The pathogenesis of malarial anemia is complex, involving both parasite and host factors. As mouse models of malaria
Publikováno v:
Frontiers in Microbiology
Severe malaria anemia is one of the most common causes of morbidity and mortality arising from infection with Plasmodium falciparum. The pathogenesis of malarial anemia is complex, involving both parasite and host factors. As mouse models of malaria
Autor:
Jessica G. Borger, Benjamin G Dewals, Daniel M. Davis, Sheila Brown, Alexander T. Phythian-Adams, Annette M. Dougall, Adam N.R. Cartwright, Cecilia Johansson, Ruud H. P. Wilbers, Rachel J. Lundie, Peter C. Cook, Lucy H. Jackson-Jones, Franca Ronchese, Andrew S. MacDonald, Lauren M. Webb, Lisa M. Connor
Publikováno v:
The EMBO Journal 36 (2017) 16
Webb, L M, Lundie, R J, Borger, J G, Brown, S, Connor, L M, Cartwright, A N R, Dougall, A M, Wilbers, R, Cook, P, Jackson-Jones, L, Phythian-Adams, A T, Johansson, C, Davis, D M, Dewals, B G, Ronchese, F & MacDonald, A 2017, ' Type I interferon is required for T helper (Th) 2 induction by dendritic cells ', EMBO Journal . https://doi.org/10.15252/embj.201695345
The EMBO Journal, 36(16), 2404-2418
The EMBO Journal
Webb, L, Lundie, R J, Borger, J G, Brown, S, Connor, L M, Cartwright, A, Dougall, A M, Wilbers, R H P, Cook, P, Jackson-Jones, L H, Phythian-Adams, A, Johansson, C, Davis, D M, Dewals, B G, Ronchese, F & MacDonald, A 2017, ' Type I interferon is required for T helper (Th) 2 induction by dendritic cells ', The EMBO Journal, vol. 36, no. 16, pp. 2404-2418 . https://doi.org/10.15252/embj.201695345
Webb, L M, Lundie, R J, Borger, J G, Brown, S, Connor, L M, Cartwright, A N R, Dougall, A M, Wilbers, R, Cook, P, Jackson-Jones, L, Phythian-Adams, A T, Johansson, C, Davis, D M, Dewals, B G, Ronchese, F & MacDonald, A 2017, ' Type I interferon is required for T helper (Th) 2 induction by dendritic cells ', EMBO Journal . https://doi.org/10.15252/embj.201695345
The EMBO Journal, 36(16), 2404-2418
The EMBO Journal
Webb, L, Lundie, R J, Borger, J G, Brown, S, Connor, L M, Cartwright, A, Dougall, A M, Wilbers, R H P, Cook, P, Jackson-Jones, L H, Phythian-Adams, A, Johansson, C, Davis, D M, Dewals, B G, Ronchese, F & MacDonald, A 2017, ' Type I interferon is required for T helper (Th) 2 induction by dendritic cells ', The EMBO Journal, vol. 36, no. 16, pp. 2404-2418 . https://doi.org/10.15252/embj.201695345
Type 2 inflammation is a defining feature of infection with parasitic worms(helminths), as well as being responsible for widespread suffering in allergies.However, the precise mechanisms involved in T helper (Th) 2 polarization bydendritic cells (DCs