Zobrazeno 1 - 10
of 105
pro vyhledávání: '"Rachel Hilton"'
Autor:
Laura M. Hack, Xue Zhang, Boris D. Heifets, Trisha Suppes, Peter J. van Roessel, Jerome A. Yesavage, Nancy J. Gray, Rachel Hilton, Claire Bertrand, Carolyn I. Rodriguez, Karl Deisseroth, Brian Knutson, Leanne M. Williams
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-11 (2023)
Abstract Ketamine commonly and rapidly induces dissociative and other altered states of consciousness (ASCs) in humans. However, the neural mechanisms that contribute to these experiences remain unknown. We used functional neuroimaging to engage key
Externí odkaz:
https://doaj.org/article/535ce071fc9c488dbbe7b117c9578f97
Autor:
Dominic Stringer, Leanne Gardner, Olivia Shaw, Brendan Clarke, David Briggs, Judith Worthington, Matthew Buckland, Guilherme Danzi, Rachel Hilton, Michael Picton, Raj Thuraisingham, Richard Borrows, Richard Baker, Keith McCullough, John Stoves, Mysore Phanish, Sapna Shah, Kin Yee Shiu, Stephen B. Walsh, Aimun Ahmed, Waqar Ayub, Janet Hegarty, Rose Tinch-Taylor, Evangelos Georgiou, Natalie Bidad, Ayşenur Kılıç, Zoe Moon, Robert Horne, Paul McCrone, Joanna Kelly, Caroline Murphy, Janet Peacock, Anthony Dorling
Publikováno v:
EClinicalMedicine, Vol 56, Iss , Pp 101819- (2023)
Summary: Background: 3% of kidney transplant recipients return to dialysis annually upon allograft failure. Development of antibodies (Ab) against human leukocyte antigens (HLA) is a validated prognostic biomarker of allograft failure. We tested whet
Externí odkaz:
https://doaj.org/article/2c4d324f492b41508cbeb5d77c800b2e
Autor:
Rachel K.Y. Hung, Elizabeth Binns-Roemer, John W. Booth, Rachel Hilton, Julie Fox, Fiona Burns, Mark Harber, Andrew Ustianowski, Lisa Hamzah, James E. Burns, Amanda Clarke, David A. Price, Stephen Kegg, Denis Onyango, Beatriz Santana-Suarez, Lucy Campbell, Kate Bramham, Claire C. Sharpe, Caroline A. Sabin, Cheryl A. Winkler, Frank A. Post, John Booth, Anele Waters, James Hand, Chris Clarke, Sarah Murphy, Maurice Murphy, Marion Campbell, Celia Richardson, Alyson Knott, Gemma Weir, Rebecca Cleig, Helena Soviarova, Lisa Barbour, Tanya Adams, Vicky Kennard, Vittorio Trevitt, Rachael Jones, Jeremy Levy, Alexandra Schoolmeester, Serah Duro, May Rabuya, Deborah Jordan, Teresa Solano, Hiromi Uzu, Karen Williams, Julianne Lwanga, Linda Ekaette Reid-Amoruso, Hannah Gamlen, Robert J. Stocker, Fiona Ryan, Karina Mahiouz, Tess Cheetham, Claire Williams, Achyuta Nori, Caroline Thomas, Sivaraj Venkateshwaran, Jessica Doctor, Andrea Berlanga, Frank Post, Leigh McQueen, Priya Bhagwandin, Bee Barbini, Emily Wandolo, Tim Appleby, Lois Driver, Sophy Parr, Hongbo Deng, Julie Barber, Andrew Crowe, Chris Taylor, Mary Poulton, Vida Boateng, Marie-Pierre Klein, Caitlin O’Brien, Samuel Ohene-Adomako, Christian Buckingham, Daniel Trotman, Killian Quinn, Kate Flanagan, Verity Sullivan, Holly Middleditch, Itty Samuel, Elizabeth Hamlyn, Candice McDonald, Ana Canoso, Emeka Agbasi, Maria Liskova, Sarah Barber, Amanda Samarawickrama, Zoe Ottaway, Claire Norcross, Amelia Oliveira, Jane Minton, Gary Lamont, Ruby Cross, Gaushiya Saiyad, Shadia Ahmed, Rebecca Ashworth, Nicola Window, J. Murira, Khine Phyu, Gabriella Lindergard, Jonathan Shaw, Sarah Holland, Claire Fox, Jan Flaherty, Margaret-Anne Bevan, Valerie George, David Chadwick, Marie Branch, Pauline Lambert, Adele Craggs, Sarah Pett, Hinal Lukha, Nina Vora, Marzia Fiorino, Maria Muller Nunez, Deirdre Sally, Erica Pool, Rebecca Matthews, David Ashley Price, Tara Stothard, Bijal Patel, Ian McVittie, Ciara Kennedy, Uli Shwab, Brendan Payne, Sarah Duncan, Jill Dixon, Mathias Schmid, Adam Evans, Christopher Duncan, Ewan Hunter, Yusri Taha, Natasha Astill, Cheryl Winkler, Victor David, Jonathan Ainsworth, Rachel Vincent, Chloe Saad, Sarah Skinner, Hocine Azzoug, Judith Russell, Tarik Moussaoui, Emily Mabonga, Donna Ward, J. Francoise, W. Larbi, Sue Mitchell, A. Manning, V. Russell, Nnenna Ngwu, Jonathan Edwards, Nargis Hemat, Tom Fernandez, Filippo Ferro, Jorge Ferreira, Alice Nightingale, Tasha Oakes-Monger, Darwin Matila, Pedro Nogueira, Victoria Mutagwanya, Catherine Cosgrove, Catherine Emily Isitt, Helen Webb, Joyce Popoola, Kate Korley, Mark Mencias, Patricia Ribeiro, Rajeshwar Ramkhelawn, Sandra Oliva Lara, Sara Sajijad, Alan Winston, Amber Shaw, Claire Petersen, Kyle Ring, Melanie Rosenvinge, Thembi Moyo, Faith Odong, Katherine Gantert, Tina Ibe, Caroline Sabin, Teresa Hill
Publikováno v:
Kidney International Reports, Vol 7, Iss 3, Pp 465-473 (2022)
Introduction: Sickle cell trait (SCT) has been associated with chronic kidney disease (CKD) in African Americans, although evidence for its impact in Africans and people with HIV is currently lacking. We conducted a cross-sectional study investigatin
Externí odkaz:
https://doaj.org/article/4cf2d54ad87e424fb52a38c5375589cf
Autor:
Lis Cordingley, Pauline A Nelson, Linda Davies, Darren Ashcroft, Christine Bundy, Carolyn Chew-Graham, Anna Chisholm, Jamie Elvidge, Matthew Hamilton, Rachel Hilton, Karen Kane, Christopher Keyworth, Alison Littlewood, Karina Lovell, Mark Lunt, Helen McAteer, Dionysios Ntais, Rosa Parisi, Christina Pearce, Martin Rutter, Deborah Symmons, Helen Young, Christopher EM Griffiths
Publikováno v:
Programme Grants for Applied Research, Vol 10, Iss 3 (2022)
Background: Psoriasis is a common, lifelong inflammatory skin disease, the severity of which can range from limited disease involving a small body surface area to extensive skin involvement. It is associated with high levels of physical and psychosoc
Externí odkaz:
https://doaj.org/article/7e81afa6e3424642b30b0b724c0a417f
Autor:
Rachel K.Y. Hung, Beatriz Santana-Suarez, Elizabeth Binns-Roemer, Lucy Campbell, Kate Bramham, Lisa Hamzah, Julie Fox, James E. Burns, Amanda Clarke, Rachel Vincent, Rachael Jones, David A. Price, Denis Onyango, Mark Harber, Rachel Hilton, John W. Booth, Caroline A. Sabin, Cheryl A. Winkler, Frank A. Post
Publikováno v:
EClinicalMedicine, Vol 38, Iss , Pp 101006- (2021)
Background: Chronic kidney disease (CKD) is a leading cause of morbidity and mortality globally. The risk of CKD is increased in people of African ancestry and with Human Immunodeficiency Virus (HIV) infection. Methods: We conducted a cross-sectional
Externí odkaz:
https://doaj.org/article/1ea3251769794c94af5bbcc2e92540e6
Autor:
Dominic Stringer, Leanne M. Gardner, Janet L. Peacock, Irene Rebollo-Mesa, Rachel Hilton, Olivia Shaw, Richard Baker, Brendan Clark, Raj C. Thuraisingham, Matthew Buckland, Michael Picton, Judith Worthington, Richard Borrows, David Briggs, Sapna Shah, Kin Yee Shiu, Keith McCullough, Mysore Phanish, Janet Hegarty, John Stoves, Aimun Ahmed, Waqar Ayub, Robert Horne, Paul McCrone, Joanna Kelly, Caroline Murphy, Anthony Dorling
Publikováno v:
Trials, Vol 20, Iss 1, Pp 1-9 (2019)
Abstract Background Chronic rejection is the single biggest cause of premature kidney graft failure. HLA antibodies (Ab) are an established prognostic biomarker for premature graft failure so there is a need to test whether treatment decisions based
Externí odkaz:
https://doaj.org/article/08a2f39e81b34e6a91eb89c65444c54f
Autor:
Allifia Abbas, Charlotte Zheng, Claire van Nispen tot Pannerden, William Newsholme, Rachel Hilton
Publikováno v:
Clinical Infection in Practice, Vol 7, Iss , Pp 100021- (2020)
Background: Acute toxoplasmosis in the transplant recipient can be a serious infection and usually represents reactivation of latent infection. Primary toxoplasmosis after transplantation is much rarer and is associated with greater morbidity and mor
Externí odkaz:
https://doaj.org/article/5a362acc5ba04d14b4e5260eac5f860f
Autor:
Sofia Christakoudi, Manohursingh Runglall, Paula Mobillo, Irene Rebollo-Mesa, Tjir-Li Tsui, Estefania Nova-Lamperti, Catharine Taube, Sonia Norris, Yogesh Kamra, Rachel Hilton, Titus Augustine, Sunil Bhandari, Richard Baker, David Berglund, Sue Carr, David Game, Sian Griffin, Philip A. Kalra, Robert Lewis, Patrick B. Mark, Stephen D. Marks, Iain MacPhee, William McKane, Markus G. Mohaupt, Estela Paz-Artal, Sui Phin Kon, Daniel Serón, Manish D. Sinha, Beatriz Tucker, Ondrej Viklický, Daniel Stahl, Robert I. Lechler, Graham M. Lord, Maria P. Hernandez-Fuentes
Publikováno v:
EBioMedicine, Vol 58, Iss , Pp 102899- (2020)
Background: Kidney transplant recipients (KTRs) with “operational tolerance” (OT) maintain a functioning graft without immunosuppressive (IS) drugs, thus avoiding treatment complications. Nevertheless, IS drugs can influence gene-expression signa
Externí odkaz:
https://doaj.org/article/3e888ca856124c02877325b343eab615
Autor:
Kin Yee Shiu, Dominic Stringer, Laura McLaughlin, Olivia Shaw, Paul Brookes, Hannah Burton, Hannah Wilkinson, Harriet Douthwaite, Tjir-Li Tsui, Adam Mclean, Rachel Hilton, Sian Griffin, Colin Geddes, Simon Ball, Richard Baker, Candice Roufosse, Catherine Horsfield, Anthony Dorling
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
RituxiCAN-C4 combined an open-labeled randomized controlled trial (RCT) in 7 UK centers to assess whether rituximab could stabilize kidney function in patients with chronic rejection, with an exploratory analysis of how B cell-depletion influenced T
Externí odkaz:
https://doaj.org/article/9ada6f057e794dd7ba43b83bcdef0472
Autor:
Henrieta Fraser, Niloufar Safinia, Nathali Grageda, Sarah Thirkell, Katie Lowe, Laura J. Fry, Cristiano Scottá, Andrew Hope, Christopher Fisher, Rachel Hilton, David Game, Paul Harden, Andrew Bushell, Kathryn Wood, Robert I. Lechler, Giovanna Lombardi
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 8, Iss C, Pp 198-209 (2018)
The concept of regulatory T cell (Treg)-based immunotherapy has enormous potential for facilitating tolerance in autoimmunity and transplantation. Clinical translation of Treg cell therapy requires production processes that satisfy the rigors of Good
Externí odkaz:
https://doaj.org/article/85e919f3eff5464fb7314ee3c37abc73