Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Rachel H. Tan"'
Autor:
Rachel H. Tan, Heather McCann, Claire E. Shepherd, Monica Pinkerton, Srestha Mazumder, Emma M. Devenney, Gabrielle L. Adler, Dominic B. Rowe, Jillian Kril, Glenda M. Halliday, Matthew C. Kiernan
Publikováno v:
Acta Neuropathologica Communications, Vol 11, Iss 1, Pp 1-12 (2023)
Abstract Background Despite the presence of significant cortical pTDP-43 inclusions of heterogeneous morphologies in patients diagnosed with amyotrophic lateral sclerosis (ALS), pathological subclassification is routinely performed in the minority of
Externí odkaz:
https://doaj.org/article/d388ba55658c42378209fd9d692b85ed
Autor:
Rachel H. Tan, Yue Yang, Woojin S. Kim, Carol Dobson-Stone, John B. Kwok, Matthew C. Kiernan, Glenda M. Halliday
Publikováno v:
Acta Neuropathologica Communications, Vol 5, Iss 1, Pp 1-7 (2017)
Abstract The identification of the TAR DNA-binding protein 43 (TDP-43) as the ubiquitinated cytoplasmic inclusions in frontotemporal lobar degeneration (FTLD) and amyotrophic lateral sclerosis (ALS) confirmed that these two diseases share similar mec
Externí odkaz:
https://doaj.org/article/7cde02c9a4dd433a81e5e80e29a4a474
Autor:
Rachel H Tan, Emma Devenney, Carol Dobson-Stone, John B Kwok, John R Hodges, Matthew C Kiernan, Glenda M Halliday, Michael Hornberger
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e105632 (2014)
Amyotrophic lateral sclerosis (ALS) and behavioural variant frontotemporal dementia (bvFTD) are multisystem neurodegenerative disorders that manifest overlapping cognitive, neuropsychiatric and motor features. The cerebellum has long been known to be
Externí odkaz:
https://doaj.org/article/f0a7319a2a1d42adb6c1d016224ef29c
Publikováno v:
Neurology. 93(19)
To assess the amount of phosphorylated and nonphosphorylated TAR DNA-binding protein 43 (TDP-43) in the motor brain regions of cases of amyotrophic lateral sclerosis (ALS) with and without repeat expansions in theThe 45-kDa phosphorylated form of TDP
Autor:
Rachel H, Tan, Jillian J, Kril, Ciara, McGinley, Mohammad, Hassani, Masami, Masuda-Suzukake, Masato, Hasegawa, Remika, Mito, Matthew C, Kiernan, Glenda M, Halliday
Publikováno v:
Annals of neurology. 79(2)
Despite evidence suggesting that the cerebellum may be targeted in amyotrophic lateral sclerosis (ALS), particularly in cases with repeat expansions in the ATXN2 and C9ORF72 genes, the integrity of cerebellar neurons has yet to be examined. The prese
Autor:
Rachel H Tan, Emma eDevenney, Matthew C Kiernan, Glenda M Halliday, John R Hodges, Michael eHornberger
Publikováno v:
Frontiers in Aging Neuroscience, Vol 7 (2015)
Frontiers in Aging Neuroscience
Frontiers in Aging Neuroscience
Although converging evidence has positioned the human cerebellum as an important relay for intact cognitive and neuropsychiatric processing, changes in this large structure remain mostly overlooked in behavioral variant frontotemporal dementia (bvFTD