Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Rachel Grimshaw"'
Autor:
Paul Workman, Ian Judson, Melani Valenti, Lloyd Kelland, Rachel Grimshaw, Florence Raynaud, Michael Walton, Udai Banerji
Purpose: To establish the pharmacokinetic and pharmacodynamic profile of the heat shock protein 90 (HSP90) inhibitor 17-allylamino, 17-demethoxygeldanamycin (17-AAG) in ovarian cancer xenograft models.Experimental Design: The effects of 17-AAG on gro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3335e1dc199534b941bc901ecc76da05
https://doi.org/10.1158/1078-0432.c.6518076
https://doi.org/10.1158/1078-0432.c.6518076
Autor:
Paul Workman, Ian Judson, Melani Valenti, Lloyd Kelland, Rachel Grimshaw, Florence Raynaud, Michael Walton, Udai Banerji
Table with PK Data
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c54c5477968423b0c7368f433bd4f63a
https://doi.org/10.1158/1078-0432.22440801.v1
https://doi.org/10.1158/1078-0432.22440801.v1
Autor:
Ian Judson, Lloyd R. Kelland, Michael I. Walton, Melani Valenti, Udai Banerji, Rachel Grimshaw, Paul Workman, Florence I. Raynaud
Publikováno v:
Clinical Cancer Research. 11:7023-7032
Purpose: To establish the pharmacokinetic and pharmacodynamic profile of the heat shock protein 90 (HSP90) inhibitor 17-allylamino, 17-demethoxygeldanamycin (17-AAG) in ovarian cancer xenograft models. Experimental Design: The effects of 17-AAG on gr
Autor:
Beatrice M, Seddon, Geoffrey S, Payne, Laura, Simmons, Ruth, Ruddle, Rachel, Grimshaw, Siew, Tan, Alison, Turner, Florence, Raynaud, Gavin, Halbert, Martin O, Leach, Ian, Judson, Paul, Workman
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 9(14)
To perform a Phase I study of SR-4554, a fluorinated 2-nitroimidazole noninvasive probe of tumor hypoxia detected by (19)F magnetic resonance spectroscopy (MRS).SR-4554 administration, on days 1 and 8, was followed by plasma sampling for pharmacokine