Zobrazeno 1 - 10
of 198
pro vyhledávání: '"Rachel F, Buckley"'
Autor:
Kwangsik Nho, Shannon L. Risacher, Liana G. Apostolova, Paula J. Bice, Jared R. Brosch, Rachael Deardorff, Kelley Faber, Martin R. Farlow, Tatiana Foroud, Sujuan Gao, Thea Rosewood, Jun Pyo Kim, Kelly Nudelman, Meichen Yu, Paul Aisen, Reisa Sperling, Basavaraj Hooli, Sergey Shcherbinin, Diana Svaldi, Clifford R. Jack, William J. Jagust, Susan Landau, Aparna Vasanthakumar, Jeffrey F. Waring, Vincent Doré, Simon M. Laws, Colin L. Masters, Tenielle Porter, Christopher C. Rowe, Victor L. Villemagne, Logan Dumitrescu, Timothy J. Hohman, Julia B. Libby, Elizabeth Mormino, Rachel F. Buckley, Keith Johnson, Hyun-Sik Yang, Ronald C. Petersen, Vijay K. Ramanan, Nilüfer Ertekin-Taner, Prashanthi Vemuri, Ann D. Cohen, Kang-Hsien Fan, M. Ilyas Kamboh, Oscar L. Lopez, David A. Bennett, Muhammad Ali, Tammie Benzinger, Carlos Cruchaga, Diana Hobbs, Philip L. De Jager, Masashi Fujita, Vaishnavi Jadhav, Bruce T. Lamb, Andy P. Tsai, Isabel Castanho, Jonathan Mill, Michael W. Weiner, for the Alzheimer’s Disease Neuroimaging Initiative (ADNI), the Department of Defense Alzheimer’s Disease Neuroimaging Initiative (DoD-ADNI), the Anti-Amyloid Treatment in Asymptomatic Alzheimer’s Study (A4 Study) and Longitudinal Evaluation of Amyloid Risk and Neurodegeneration (LEARN), the Australian Imaging, Biomarker & Lifestyle Study (AIBL), Andrew J. Saykin
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Determining the genetic architecture of Alzheimer’s disease pathologies can enhance mechanistic understanding and inform precision medicine strategies. Here, we perform a genome-wide association study of cortical tau quantified by positron
Externí odkaz:
https://doaj.org/article/534dba93d5bf4620975ce9a0f564baf7
Autor:
Rory Boyle, Diana L. Townsend, Hannah M. Klinger, Catherine E. Scanlon, Ziwen Yuan, Gillian T. Coughlan, Mabel Seto, Zahra Shirzadi, Wai-Ying Wendy Yau, Roos J. Jutten, Christoph Schneider, Michelle E. Farrell, Bernard J. Hanseeuw, Elizabeth C. Mormino, Hyun-Sik Yang, Kathryn V. Papp, Rebecca E. Amariglio, Heidi I. L. Jacobs, Julie C. Price, Jasmeer P. Chhatwal, Aaron P. Schultz, Michael J. Properzi, Dorene M. Rentz, Keith A. Johnson, Reisa A. Sperling, Timothy J. Hohman, Michael C. Donohue, Rachel F. Buckley, for the Alzheimer’s Disease Neuroimaging Initiative
Publikováno v:
Alzheimer’s Research & Therapy, Vol 16, Iss 1, Pp 1-16 (2024)
Abstract Background Leveraging Alzheimer’s disease (AD) imaging biomarkers and longitudinal cognitive data may allow us to establish evidence of cognitive resilience (CR) to AD pathology in-vivo. Here, we applied latent class mixture modeling, adju
Externí odkaz:
https://doaj.org/article/533e6b89a4fd4deeb58b8bf4d29de93c
Autor:
Muhammad Ali, Derek B. Archer, Priyanka Gorijala, Daniel Western, Jigyasha Timsina, Maria V. Fernández, Ting-Chen Wang, Claudia L. Satizabal, Qiong Yang, Alexa S. Beiser, Ruiqi Wang, Gengsheng Chen, Brian Gordon, Tammie L. S. Benzinger, Chengjie Xiong, John C. Morris, Randall J. Bateman, Celeste M. Karch, Eric McDade, Alison Goate, Sudha Seshadri, Richard P. Mayeux, Reisa A. Sperling, Rachel F. Buckley, Keith A. Johnson, Hong-Hee Won, Sang-Hyuk Jung, Hang-Rai Kim, Sang Won Seo, Hee Jin Kim, Elizabeth Mormino, Simon M. Laws, Kang-Hsien Fan, M. Ilyas Kamboh, Prashanthi Vemuri, Vijay K. Ramanan, Hyun-Sik Yang, Allen Wenzel, Hema Sekhar Reddy Rajula, Aniket Mishra, Carole Dufouil, Stephanie Debette, Oscar L. Lopez, Steven T. DeKosky, Feifei Tao, Michael W. Nagle, Knight Alzheimer Disease Research Center (Knight ADRC), the Dominantly Inherited Alzheimer Network (DIAN), Alzheimer’s Disease Neuroimaging Initiative (ADNI), ADNI-DOD, A4 Study Team, the Australian Imaging Biomarkers, Lifestyle (AIBL) Study, Timothy J. Hohman, Yun Ju Sung, Logan Dumitrescu, Carlos Cruchaga
Publikováno v:
Acta Neuropathologica Communications, Vol 11, Iss 1, Pp 1-20 (2023)
Abstract Amyloid PET imaging has been crucial for detecting the accumulation of amyloid beta (Aβ) deposits in the brain and to study Alzheimer’s disease (AD). We performed a genome-wide association study on the largest collection of amyloid imagin
Externí odkaz:
https://doaj.org/article/9eca2e70df9440858512dc974cf5a69a
Autor:
Prokopis C. Prokopiou, Nina Engels-Domínguez, Kathryn V. Papp, Matthew R. Scott, Aaron P. Schultz, Christoph Schneider, Michelle E. Farrell, Rachel F. Buckley, Yakeel T. Quiroz, Georges El Fakhri, Dorene M. Rentz, Reisa A. Sperling, Keith A. Johnson, Heidi I. L. Jacobs
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
Older individuals exhibiting diminished function of the locus coeruleus while learning new information show faster cognitive decline that is typical for Alzheimer’s disease.
Externí odkaz:
https://doaj.org/article/064e0e4a05864dea8910777843fb04ad
Autor:
Mark A. Dubbelman, Roos J. Jutten, Sarah E. Tomaszewski Farias, Rebecca E. Amariglio, Rachel F. Buckley, Pieter Jelle Visser, Dorene M. Rentz, Keith A. Johnson, Michael J. Properzi, Aaron Schultz, Nancy Donovan, Jennifer R. Gatchell, Charlotte E. Teunissen, Bart N. M. Van Berckel, Wiesje M. Van der Flier, Reisa A. Sperling, Kathryn V. Papp, Philip Scheltens, Gad A. Marshall, Sietske A. M. Sikkes, for the Alzheimer Disease Neuroimaging Initiative, National Alzheimer’s Coordinating Center, the Harvard Aging Brain Study, the Alzheimer Dementia Cohort
Publikováno v:
Alzheimer’s Research & Therapy, Vol 12, Iss 1, Pp 1-11 (2020)
Abstract Background Impairment in daily functioning is a clinical hallmark of dementia. Difficulties with “instrumental activities of daily living” (IADL) seem to increase gradually over the course of Alzheimer’s disease (AD), before dementia o
Externí odkaz:
https://doaj.org/article/89c52c5343444b7788cbea71dd84912f
Autor:
Roos J. Jutten, Dorene M. Rentz, Jessie F. Fu, Danielle V. Mayblyum, Rebecca E. Amariglio, Rachel F. Buckley, Michael J. Properzi, Paul Maruff, Craig E. Stark, Michael A. Yassa, Keith A. Johnson, Reisa A. Sperling, Kathryn V. Papp
Publikováno v:
Frontiers in Aging Neuroscience, Vol 13 (2022)
Introduction: We investigated whether monthly assessments of a computerized cognitive composite (C3) could aid in the detection of differences in practice effects (PE) in clinically unimpaired (CU) older adults, and whether diminished PE were associa
Externí odkaz:
https://doaj.org/article/83d53e09c2fc4f4fbc2793c77dfd9731
Autor:
Rachel F. Buckley, Sietske Sikkes, Victor L. Villemagne, Elizabeth C. Mormino, Jennifer S. Rabin, Samantha Burnham, Kathryn V. Papp, Vincent Doré, Colin L. Masters, Michael J. Properzi, Aaron P. Schultz, Keith A. Johnson, Dorene M. Rentz, Reisa A. Sperling, Rebecca E. Amariglio
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 11, Iss 1, Pp 670-678 (2019)
Abstract Introduction We aimed to examine the contribution of subjective cognitive decline (SCD) to reduce the number of β‐amyloid (Aβ) positron emission tomography scans required for recruiting Aβ+ clinically normal individuals in clinical tria
Externí odkaz:
https://doaj.org/article/33f33f49edec41f7bf0526b2cb1f1d20
Autor:
Matthew R. Scott, Olivia L. Hampton, Rachel F. Buckley, Jasmeer P. Chhatwal, Bernard J. Hanseeuw, Heidi IL. Jacobs, Michael J. Properzi, Justin S. Sanchez, Keith A. Johnson, Reisa A. Sperling, Aaron P. Schultz
Publikováno v:
NeuroImage, Vol 220, Iss , Pp 116991- (2020)
Neurofibrillary tau tangles are a hallmark pathology of Alzheimer's disease (AD) and are more closely associated with AD-related cortical atrophy and symptom severity than amyloid-beta (Aβ). However, studies regarding the effect of tau on longitudin
Externí odkaz:
https://doaj.org/article/e277ebee1046491c8973965075c1da79
Autor:
Jennifer S. Rabin, Taylor E. Neal, Hannah E. Nierle, Sietske A.M. Sikkes, Rachel F. Buckley, Rebecca E. Amariglio, Kathryn V. Papp, Dorene M. Rentz, Aaron P. Schultz, Keith A. Johnson, Reisa A. Sperling, Trey Hedden
Publikováno v:
NeuroImage: Clinical, Vol 28, Iss , Pp 102400- (2020)
Objective: To identify a parsimonious set of markers that optimally predicts subsequent clinical progression from normal to mild cognitive impairment (MCI). Methods: 250 clinically normal adults (mean age = 73.6 years, SD = 6.0) from the Harvard Agin
Externí odkaz:
https://doaj.org/article/48a291a180d34d0cb5ee32a1834b5a83
Autor:
Olivia L. Hampton, Rachel F. Buckley, Lyssa K. Manning, Matthew R. Scott, Michael J. Properzi, Cleofé Peña-Gómez, Heidi I.L. Jacobs, Jasmeer P. Chhatwal, Keith A. Johnson, Reisa A. Sperling, Aaron P. Schultz
Publikováno v:
NeuroImage: Clinical, Vol 28, Iss , Pp 102407- (2020)
Proteinopathies are key elements in the pathogenesis of age-related neurodegenerative diseases, particularly Alzheimer’s disease (AD), with the nature and location of the proteinopathy characterizing much of the disease phenotype. Susceptibility of
Externí odkaz:
https://doaj.org/article/9dd0e669cf9846008e81c5c15a1e2ed6