Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Rachel E. Thomas"'
Autor:
Martijn G. S. Rutten, Yu Lei, Joanne H. Hoogerland, Vincent W. Bloks, Hong Yang, Trijnie Bos, Kishore A. Krishnamurthy, Aycha Bleeker, Mirjam H. Koster, Rachel E. Thomas, Justina C. Wolters, Hilda van den Bos, Gilles Mithieux, Fabienne Rajas, Adil Mardinoglu, Diana C. J. Spierings, Alain de Bruin, Bart van de Sluis, Maaike H. Oosterveer
Publikováno v:
Cancer & Metabolism, Vol 11, Iss 1, Pp 1-11 (2023)
Abstract Background Glycogen storage disease type 1a (GSD Ia) is an inborn error of metabolism caused by a defect in glucose-6-phosphatase (G6PC1) activity, which induces severe hepatomegaly and increases the risk for liver cancer. Hepatic GSD Ia is
Externí odkaz:
https://doaj.org/article/176971327ab64839a0921d89e984a866
Autor:
Christina Kijan, Sanne Hugen, Rachel E. Thomas, Anita M. Oberbauer, Peter A. J. Leegwater, Hille Fieten, Alexander J. German, Paul J. J. Mandigers
Publikováno v:
Animals, Vol 13, Iss 9, p 1532 (2023)
Gastric carcinoma is generally considered to be a rare disease in dogs, carrying a grave prognosis. However, in the Tervueren and Groenendael varieties of the Belgian Shepherd dog breed, the disease is highly prevalent. While histopathology is the go
Externí odkaz:
https://doaj.org/article/17c30d0eb8f345858af7254b7f981690
Autor:
Onne A H O Ronda, Bert J M van de Heijning, Alain de Bruin, Rachel E Thomas, Ingrid Martini, Martijn Koehorst, Albert Gerding, Mirjam H Koster, Vincent W Bloks, Angelika Jurdzinski, Niels L Mulder, Rick Havinga, Eline M van der Beek, Dirk-Jan Reijngoud, Folkert Kuipers, Henkjan J Verkade
Publikováno v:
PLoS ONE, Vol 15, Iss 9, p e0232069 (2020)
Mouse models are frequently used to study mechanisms of human diseases. Recently, we observed a spontaneous bimodal variation in liver weight in C57BL/6JOlaHsd mice fed a semisynthetic diet. We now characterized the spontaneous variation in liver wei
Externí odkaz:
https://doaj.org/article/7a34a45721614e4783dbcd572ecf0fb3
Autor:
Wenxuan Zhang, Rachel E. Thomas, Johan W. Jonker, Justina C. Wolters, Fentaw Abegaz, Janine K. Kruit, Ronald van Os, Marleen B Dommerholt, Barbara M. Bakker, Dirk-Jan Reijngoud, Maaike Blankestijn, Ydwine T. van der Veen, Marcel A. Vieira-Lara, Albert Gerding
Publikováno v:
BMC Biology, Vol 19, Iss 1, Pp 1-18 (2021)
BMC Biology, 19(1):154. BioMed Central Ltd.
BMC Biology
Vieira-Lara, M A, Dommerholt, M B, Zhang, W, Blankestijn, M, Wolters, J C, Abegaz, F, Gerding, A, van der Veen, Y T, Thomas, R, van Os, R P, Reijngoud, D J, Jonker, J W, Kruit, J K & Bakker, B M 2021, ' Age-related susceptibility to insulin resistance arises from a combination of CPT1B decline and lipid overload ', BMC Biology, vol. 19, no. 1, 154 . https://doi.org/10.1186/s12915-021-01082-5
BMC Biology, 19(1):154. BioMed Central Ltd.
BMC Biology
Vieira-Lara, M A, Dommerholt, M B, Zhang, W, Blankestijn, M, Wolters, J C, Abegaz, F, Gerding, A, van der Veen, Y T, Thomas, R, van Os, R P, Reijngoud, D J, Jonker, J W, Kruit, J K & Bakker, B M 2021, ' Age-related susceptibility to insulin resistance arises from a combination of CPT1B decline and lipid overload ', BMC Biology, vol. 19, no. 1, 154 . https://doi.org/10.1186/s12915-021-01082-5
Background The skeletal muscle plays a central role in glucose homeostasis through the uptake of glucose from the extracellular medium in response to insulin. A number of factors are known to disrupt the normal response to insulin leading to the emer
Autor:
Justina C. Wolters, Michel van Weeghel, Gilles Mithieux, Aycha Bleeker, Folkert Kuipers, Vincent W. Bloks, Fabienne Rajas, Yu Lei, Joanne A Hoogerland, Henk Wolters, Maaike H. Oosterveer, Trijnie Bos, Alain de Bruin, Brenda S. Hijmans, Rachel E. Thomas, Theo H. van Dijk, Riekelt H. Houtkooper
Publikováno v:
Hepatology (Baltimore, Md.)
Hepatology
Hepatology, Wiley-Blackwell, 2020, 72 (5), pp.1638-1653. ⟨10.1002/hep.31198⟩
Hepatology (Baltimore, Md.), 72(5), 1638-1653. John Wiley and Sons Ltd
Hepatology
Hepatology, Wiley-Blackwell, 2020, 72 (5), pp.1638-1653. ⟨10.1002/hep.31198⟩
Hepatology (Baltimore, Md.), 72(5), 1638-1653. John Wiley and Sons Ltd
International audience; Background and aims: Glycogen storage disease (GSD) type 1a is an inborn error of metabolism caused by defective glucose-6-phosphatase catalytic subunit (G6PC) activity. Patients with GSD 1a exhibit severe hepatomegaly due to
Autor:
Jolle Kirpensteijn, Rachel E. Thomas, Sebastiaan A. van Nimwegen, Sara S. D. S. Janssens, Anneleen L. Spillebeen
Publikováno v:
Veterinary Surgery. 46:467-477
Objective To compare Sonicision cordless ultrasonic dissector (SCUD) to LigaSure vessel sealing device (LVSD) for laparoscopic ovariectomy (Lap OVE) in dogs. Study design Randomized, paired prospective clinical trial. Animals Client-owned dogs (n = 2
Publikováno v:
Veterinary and Comparative Oncology. 15:692-705
Gastric carcinoma (GC) is the most common neoplasm in the stomach of dogs. Although incidence in the general population is reported to be low, breed-specific GC has a high incidence. Median age at presentation ranges from 8 to approximately 10 years.
Autor:
Bart Westendorp, Stefan Schulte-Merker, M Zijp, W J Bakker, B T Hien, Bart Weijts, Rachel E. Thomas, L M Martínez-López, A. de Bruin, Ingrid Thurlings
Publikováno v:
Oncogene, 37, 271. Nature Publishing Group
ONCOGENE, 37(2), 271-276. Nature Publishing Group
Oncogene, 37(2), 271-276. Nature Publishing Group
Oncogene, 37(2), 271. Nature Publishing Group
Oncogene
ONCOGENE, 37(2), 271-276. Nature Publishing Group
Oncogene, 37(2), 271-276. Nature Publishing Group
Oncogene, 37(2), 271. Nature Publishing Group
Oncogene
Atypical E2F transcription factors (E2F7 and E2F8) function as key regulators of cell cycle progression and their inactivation leads to spontaneous cancer formation in mice. However, the mechanism of the tumor suppressor functions of E2F7/8 remain ob
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::365844f8d9941687f94eb1d86431a330
https://dspace.library.uu.nl/handle/1874/388249
https://dspace.library.uu.nl/handle/1874/388249
Autor:
Rachel E. Thomas, Andrew M. Hanby, Cheryl Gillett, Elinor J. Sawyer, Andrew Rowan, Richard Poulsom, Sunil R. Lakhani, Ian Tomlinson, Paul Ellis, Ian O. Ellis
In a previous study of phyllodes tumours, it has been shown that both the stroma and the epithelium can exhibit distinct molecular changes, suggesting that both are part of the neoplastic process. In view of this finding, it was decided to study stro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20cd3fad385ee7d7361b836f2fb1a407
https://ora.ox.ac.uk/objects/uuid:1f344794-319f-4006-a487-d5140fd0e9b6
https://ora.ox.ac.uk/objects/uuid:1f344794-319f-4006-a487-d5140fd0e9b6
Autor:
Anneleen L, Spillebeen, Sara S D S, Janssens, Rachel E, Thomas, Jolle, Kirpensteijn, Sebastiaan A, van Nimwegen
Publikováno v:
Veterinary surgery : VS. 46(4)
To compare Sonicision cordless ultrasonic dissector (SCUD) to LigaSure vessel sealing device (LVSD) for laparoscopic ovariectomy (Lap OVE) in dogs.Randomized, paired prospective clinical trial.Client-owned dogs (n = 22) presented for elective Lap OVE