Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Rachel E. Stephenson"'
Autor:
Torey R Arnold, Joseph H Shawky, Rachel E Stephenson, Kayla M Dinshaw, Tomohito Higashi, Farah Huq, Lance A Davidson, Ann L Miller
Publikováno v:
eLife, Vol 8 (2019)
Cellular forces sculpt organisms during development, while misregulation of cellular mechanics can promote disease. Here, we investigate how the actomyosin scaffold protein anillin contributes to epithelial mechanics in Xenopus laevis embryos. Increa
Externí odkaz:
https://doaj.org/article/b2e8d36113274923811bc67c9beb8534
Autor:
Tomohito Higashi, Rachel E. Stephenson, Cornelia Schwayer, Karla Huljev, Carl-Philipp Heisenberg, Hideki Chiba, Ann L. Miller
Epithelial barrier function is commonly analyzed using transepithelial electrical resistance (TER), which measures the ion flux across epithelia, or by adding traceable macromolecules to one side of the epithelium and monitoring their passage to the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0b9e220f11b88b9f9097ef228a2b4f41
https://doi.org/10.1101/2022.09.27.509705
https://doi.org/10.1101/2022.09.27.509705
Autor:
Saranyaraajan Varadarajan, Shahana A. Chumki, Rachel E. Stephenson, Eileen R. Misterovich, Jessica L. Wu, Claire E. Dudley, Ivan S. Erofeev, Andrew B. Goryachev, Ann L. Miller
Publikováno v:
Varadarajan, S, Chumki, S A, Stephenson, R, Misterovich, E R, Wu, J L, Dudley, C E, Erofeev, I, Goryachev, A B & Miller, A L 2022, ' Mechanosensitive calcium flashes promote sustained RhoA activation during tight junction remodeling ', Journal of Cell Biology, vol. 221, no. 4, e202105107 . https://doi.org/10.1083/jcb.202105107
Epithelial cell–cell junctions remodel in response to mechanical stimuli to maintain barrier function. Previously, we found that local leaks in tight junctions (TJs) are rapidly repaired by local, transient RhoA activation, termed “Rho flares,”
Publikováno v:
PLoS Pathogens, Vol 8, Iss 6, p e1002744 (2012)
Staphylococcus aureus is an opportunistic pathogen that colonizes the skin and mucosal surfaces of mammals. Persistent staphylococcal infections often involve surface-associated communities called biofilms. Here we report the discovery of a novel ext
Externí odkaz:
https://doaj.org/article/abfa376ffbaa4b7c86a78423f9933524
Publikováno v:
J Cell Sci
Epithelial cells form tissues that generate biological barriers in the body. Tight junctions (TJs) are responsible for maintaining a selectively permeable seal between epithelial cells, but little is known about how TJs dynamically remodel in respons
Publikováno v:
PLoS Pathogens, Vol 7, Iss 7, p e1002104 (2011)
Staphylococcus aureus nasal colonization is an important risk factor for community and nosocomial infection. Despite the importance of S. aureus to human health, molecular mechanisms and host factors influencing nasal colonization are not well unders
Externí odkaz:
https://doaj.org/article/9d4fe456022f4260b4ba21b64ac7863c
Publikováno v:
Experimental Cell Research. 358:20-30
Epithelial tissues are defined by polarized epithelial cells that are integrated into tissues and exhibit barrier function in order to regulate what is allowed to pass between cells. Cell-cell junctions must be stable enough to promote barrier functi
Autor:
Rachel E. Stephenson, Torey R. Arnold, Ann L. Miller, Joseph H. Shawky, Lance A. Davidson, Farah Huq, Tomohito Higashi, Kayla M Dinshaw
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cf71ed098b19d2145c201b68f6a90688
https://doi.org/10.7554/elife.39065.035
https://doi.org/10.7554/elife.39065.035
Autor:
Farah Huq, Torey R. Arnold, Ann L. Miller, Lance A. Davidson, Joseph H. Shawky, Tomohito Higashi, Rachel E. Stephenson, Kayla M Dinshaw
Publikováno v:
eLife, Vol 8 (2019)
eLife
eLife
Cellular forces sculpt organisms during development, while misregulation of cellular mechanics can promote disease. Here, we investigate how the actomyosin scaffold protein anillin contributes to epithelial mechanics in Xenopus laevis embryos. Increa
Publikováno v:
Molecular Biology of the Cell
Reorganization of the actin cytoskeleton is crucial for cellular processes, including cytokinesis and cell–cell junction remodeling. Formins are conserved processive actin-polymerizing machines that regulate actin dynamics by nucleating, elongating