Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Rachel E. Giessert"'
Autor:
William J. Greenlee, Rumin Zhang, Linda B. Fleming, Ulrich Iserloh, Murali Rajagopalan, Tanweer A. Khan, Rachel E. Giessert, Madhu Chintala, Jesse K. Wong, Brandy Courneya, Peter Orth, Johannes H. Voigt, Liwu Hong, Charles R. Heap, Hongwu Wang, Robert Mazzola, Andrew J. Zych, Thomas Bara, Walter A. Korfmacher, Kristina Moore, Samuel A. Sakwa, Henry M. Vaccaro, Sudipta Roy, John W. Clader, John P. Caldwell, Michael Czarniecki, Ruth A. Duffy, Mckittrick Brian A, Corey Strickland, George Boykow, Ying Huang, Soumya Mitra, Xian Liang, Josien Hubert B
Publikováno v:
Bioorganicmedicinal chemistry letters. 25(7)
The development of renin inhibitors with favorable oral pharmacokinetic profiles has been a longstanding challenge for the pharmaceutical industry. As part of our work to identify inhibitors of BACE1, we have previously developed iminopyrimidinones a
Publikováno v:
The Journal of organic chemistry. 74(24)
A total synthesis of the racemic natural product tylophorine [(+/-)-1] has been demonstrated using the palladium-catalyzed carboamination method developed by Wolfe and co-workers. In this case, an electron-rich aryl bromide 18 was prepared in four st
Autor:
Khalil A. Abboud, Roslyn S. Butler, Ronald K. Castellano, Ion Ghiviriga, Alisha M. Martin, Rachel E. Giessert
Publikováno v:
Chemical Communications. :4413
The first discrete, self-complementary, quadruply hydrogen-bonded complexes based on the 2,6-diaminopurine (DAP) scaffold have been prepared; regioselective urea formation at the C2 amino group of the heterocycle allows intermolecular dimerization (K